Navigation Links
New method to treat malaria in pregnant women

In West Africa, a new methodology used to treat pregnant women suffering from malaria was found to be safe and effective.// It was found out after team in Ghana and at the London School of Hygiene & Tropical Medicine (LSHTM) conducted a radomised trial.

Complete elimination of the malarial parasite without any serious side effects in the women being treated was observed when they were treated either only with the drug amodiaquine or in combination with sulphadoxine-pyrimethamine (SP).

The study, carried out among pregnant women who attended antenatal clinics at a district hospital in Ghana, is published in today's Lancet. The research team was based jointly at St Theresa's Hospital, Nkoranza, Ghana and at LSHTM.

Malaria parasites are becoming increasingly resistant to choloroquine and sulphadoxine-pyrimethamine (SP) across Africa and there is a need to find new drugs which are safe and well tolerated. Most countries in Africa are adopting artesunate-based combination therapy (ACT) as the preferred first line treatment but there is insufficient information as to its safety of ACT during pregnancy. There are concerns that ACT might have a deleterious effect on the developing embryo, particularly when given during the first trimester of pregnancy.

The extent of drug resistance is not as high in west Africa as it is in east Africa, so the authors sought to determine whether amodiaquine, which is effective in some areas with chloroquine resistance, given alone or in combination with SP might be an effective and safe treatment to use until the safety of ACT treatment in pregnancy has been be established.

They screened pregnant women with a gestational age of 16 weeks or more for the malaria parasite and those who tested positive (900 women) were enrolled, and randomly treated with four different regimens. Parasitological failure by day 28 was 14%, 11%, 3% and 0% in the women assigned choloroquine, SP, amodiaquine, and am odiaquine plus SP respectively.

Professor Brian Greenwood, Clinician and Epidemiologist at LSHTM, and one of the study's authors, comments: 'Malaria in pregnancy poses a threat to both the mother and the foetus. Previous studies had already found amodiaquine alone or in combination with SP to be an effective treatment of malaria in children in west Africa, but our research confirms that this is also true for pregnant women. No serious side-effects were noted and the treatment was well tolerated by the majority of women who took part in the trial'.

Source-Eurekalert
GYT
'"/>




Related medicine news :

1. New methods to prevent injury of patients
2. A new method to help smokers quit
3. Bioengineering production strains - Microbia develops new methods
4. New method of measuring arterial stiffness in elderly hypertensives
5. New and easier method of radiation
6. Glucommander: A safe and simple method of glycemic control
7. The weight loss reality check – Do Fad diets and short-cut methods actually work
8. Novel method conceived, to achieve genome-wide gene silencing.
9. Cigarette companies adopt devious methods to ensure customer patronage
10. Novel methods to view how a drug attaches to a cell
11. Thyroid hormone treatment hastens recovery after cardiac surgery
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/26/2017)... ... July 26, 2017 , ... “We are thrilled to be partnering with ... to schedule an appointment online in real time,” said Keith English, LocalMed CEO. “Allowing ... directory will bring more Six Month Smiles patients to their providers.” , Each month, ...
(Date:7/26/2017)... ... July 26, 2017 , ... Isodiol ... global cannabis innovator, specializing in the development of pharmaceutical and consumer products, announces ... 2017 to June 30, 2017. Iso International LLC recorded unaudited fiscal Q1 profits ...
(Date:7/26/2017)... ... 26, 2017 , ... BioPlus Specialty Pharmacy (BioPlus), ... of the HCV Treatment Path app (version 4.4.0) to keep health care providers ... All of the latest HCV medications are included in this app, including Vosevi™ ...
(Date:7/25/2017)... , ... July 25, 2017 , ... Summers in Palm ... the air conditioner — think homemade gourmet ice cream, sparkling pools, and mile-high fun. ... shop featuring fun mugs, journals, and other must-have knick knacks. Ice cream and sorbet ...
(Date:7/25/2017)... ... July 25, 2017 , ... SureVest Insurance ... services to communities across North Carolina, is launching a charity event in conjunction ... support for the ongoing fight against bladder cancer. , The Bladder Cancer Advocacy ...
Breaking Medicine News(10 mins):
(Date:7/24/2017)... IBM (NYSE: IBM ) has been recognized as a ... for the fourth year in a row. 1 ... the Leaders quadrant have the highest scores for their Ability ... Leaders quadrant has the market share, credibility, and marketing and ... These vendors demonstrate a clear understanding of market needs; they ...
(Date:7/21/2017)... and RESEARCH TRIANGLE PARK, N.C. ... Corporation (NASDAQ: UTHR ) announced today that ... before the market opens on Thursday, July 27, 2017. ... host a teleconference on Thursday, July 27, 2017, at ... dialing 1-877-351-5881, with international callers dialing 1-970-315-0533.  A rebroadcast ...
(Date:7/20/2017)... , July 20, 2017  Prime Therapeutics LLC (Prime) released ... , M.D., following today,s Institute for Clinical and Economic Review,s ... on the effectiveness and value of abuse-deterrent formulations (ADF) of ... policy roundtable at the meeting. ... material cost benefit to the use of abuse-deterrent formulations (ADF) ...
Breaking Medicine Technology: