Navigation Links
New method to treat malaria in pregnant women

In West Africa, a new methodology used to treat pregnant women suffering from malaria was found to be safe and effective.// It was found out after team in Ghana and at the London School of Hygiene & Tropical Medicine (LSHTM) conducted a radomised trial.

Complete elimination of the malarial parasite without any serious side effects in the women being treated was observed when they were treated either only with the drug amodiaquine or in combination with sulphadoxine-pyrimethamine (SP).

The study, carried out among pregnant women who attended antenatal clinics at a district hospital in Ghana, is published in today's Lancet. The research team was based jointly at St Theresa's Hospital, Nkoranza, Ghana and at LSHTM.

Malaria parasites are becoming increasingly resistant to choloroquine and sulphadoxine-pyrimethamine (SP) across Africa and there is a need to find new drugs which are safe and well tolerated. Most countries in Africa are adopting artesunate-based combination therapy (ACT) as the preferred first line treatment but there is insufficient information as to its safety of ACT during pregnancy. There are concerns that ACT might have a deleterious effect on the developing embryo, particularly when given during the first trimester of pregnancy.

The extent of drug resistance is not as high in west Africa as it is in east Africa, so the authors sought to determine whether amodiaquine, which is effective in some areas with chloroquine resistance, given alone or in combination with SP might be an effective and safe treatment to use until the safety of ACT treatment in pregnancy has been be established.

They screened pregnant women with a gestational age of 16 weeks or more for the malaria parasite and those who tested positive (900 women) were enrolled, and randomly treated with four different regimens. Parasitological failure by day 28 was 14%, 11%, 3% and 0% in the women assigned choloroquine, SP, amodiaquine, and am odiaquine plus SP respectively.

Professor Brian Greenwood, Clinician and Epidemiologist at LSHTM, and one of the study's authors, comments: 'Malaria in pregnancy poses a threat to both the mother and the foetus. Previous studies had already found amodiaquine alone or in combination with SP to be an effective treatment of malaria in children in west Africa, but our research confirms that this is also true for pregnant women. No serious side-effects were noted and the treatment was well tolerated by the majority of women who took part in the trial'.

Source-Eurekalert
GYT
'"/>




Related medicine news :

1. New methods to prevent injury of patients
2. A new method to help smokers quit
3. Bioengineering production strains - Microbia develops new methods
4. New method of measuring arterial stiffness in elderly hypertensives
5. New and easier method of radiation
6. Glucommander: A safe and simple method of glycemic control
7. The weight loss reality check – Do Fad diets and short-cut methods actually work
8. Novel method conceived, to achieve genome-wide gene silencing.
9. Cigarette companies adopt devious methods to ensure customer patronage
10. Novel methods to view how a drug attaches to a cell
11. Thyroid hormone treatment hastens recovery after cardiac surgery
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/5/2016)... ... February 05, 2016 , ... Successful recruitment ... new clinical and scientific initiatives have all marked the last 12 months at ... and CEO of the nation’s oldest cancer center, Candace S. Johnson, PhD, outlined ...
(Date:2/5/2016)... York, New York (PRWEB) , ... February 05, 2016 , ... ... life? The answer may be at the tips of your toes. Foot massage, whether ... as well as pure comfort and relaxation. The American Board of Multiple Specialties ...
(Date:2/5/2016)... ... February 05, 2016 , ... US Sports Camps ... in Dover, NH to direct high-performance kids yoga training. ChildLight Yoga Studio is centrally ... one hour from Boston. , ChildLight Yoga Studio founder Lisa Flynn expresses her excitement, ...
(Date:2/5/2016)... ... February 05, 2016 , ... Give To Cure ... search for and donate to Give To Cure’s campaign that is crowdfunding clinical trials ... users make and share payments through a smart device. In 2015 alone, Venmo processed ...
(Date:2/5/2016)... (PRWEB) , ... February 05, 2016 , ... Dr. Justin ... announce their 2nd Annual No Cost Dental Day to individuals in need. The event ... purpose of this No Cost Dental Day is to provide dental care to community ...
Breaking Medicine News(10 mins):
(Date:2/4/2016)... , Feb. 4, 2016  SciClone Pharmaceuticals, Inc. ... it has entered into a settlement agreement with ... fully resolving the SEC,s investigation into possible violations ... the terms of the settlement agreement, SciClone has ... including disgorgement, pre-judgment interest and a penalty.  This ...
(Date:2/4/2016)... Feb. 4, 2016 Global Immunology Market ... to drive long-term market growth Summary ... of chronic disorders that affect 5–7% of western ... of their symptoms and key patient demographics, they ... immune pathways and an inappropriate immune response. Generally, ...
(Date:2/4/2016)... DIEGO, Feb. 4, 2016  Aethlon Medical, Inc. ... affinity biofiltration devices to treat life-threatening diseases, today ... 2016 ended December 31, 2015. ... objectives set forth in our last quarterly call, ... reinforce our long-term objective to establish the Aethlon ...
Breaking Medicine Technology: