Navigation Links
New fertility drug development techniques by Organon

In the 7th International Symposium on GnRH Analogs in Cancer and Human Reproduction, Organon presented new techniques of development of fertility drugs. Organon scientists have succeeded in customizing the follicle-stimulating hormone(FSH) molecule by adding a hybrid subunit, which extends FSH's active life. This was achieved through an international collaboration. This longer active life will mean fewer injections for the infertile patient, making the treatment less difficult// and more patient-friendly. The company indicated that a long-acting form of the genetically-produced fertility drug, Puregon(rFSH), has moved into the dose-finding phase of its development using the latest techniques of "knowledge driven drug development" (KD3). These new techniques model the drug's underlying mechanisms, and use that information to support decisions about doses, dose regimens and design of future trials.

Organon is also in the process of developing oral tablet formulation alternative to the injectable hormone hCG (human chorionic gonadotropin). hCG has been used, in the past 30 years, to make ovulation and final oocyte maturation take place with precise timing. However, it has only been available in the injectable form due to its high molecular weight. Now, scientists have identified through high-throughput screening, compounds similar to hCG, but with lower molecular weight. These compounds have been optimized with respect to potency, selectivity and safety. The new compound, an LH/hCG agonistic agent, interacts with the human LH receptor just like LH (and hCG). Scientists carried out pre-clinical tests of this LH agonist in rats and found that it induced ovulation after a single oral dose and that fertilization of the ovulated eggs resulted in the normal implantation of healthy embryos in these rats. The scientists at Organon who are also exploring the IVF cycle concluded that this oral compound could also play a role in other infertility indications or at othe
'"/>




Page: 1 2

Related medicine news :

1. Male infertility in relation to cancer
2. Male infertility in relation to pesticide
3. Infertility in relation with virus
4. Shapely sperm-a valuable indicator of fertility
5. Relief to pregnant women using fertility drugs
6. How to repeal male infertility?
7. Benefits in fertility procedures
8. Endometriosis connected to fertility
9. Mountain biking connected to infertility
10. Reduced fertility in men who mountain bike
11. Infertility may result from bone fragments
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New fertility drug development techniques Organon

(Date:7/31/2015)... (PRWEB) , ... July 31, 2015 , ... ... new industry players to know in predictive health analytics , Jvion continues ... technologies. The firm creates predictive software that targets patient and population level illness ...
(Date:7/31/2015)... ... 2015 , ... There’s no better way to enjoy the summer weather than ... the next meal, making July the most appropriate to be National Hot Dog Month. ... , Make the next cookout different than the ones in the past. Celebrate National ...
(Date:7/31/2015)... (PRWEB) , ... July 31, 2015 , ... M3 USA ... excited to launch three new Board Exam Courses. , The additions of Gastroenterology, ... Board Exam Prep from MDLinx makes preparing for the exam easy and painless. ...
(Date:7/31/2015)... , ... July 31, 2015 , ... Well-known for its ... offering wedding cakes with custom designs, making life just a little bit ... designed wedding cakes for each customer who orders one. , The bakery provides a ...
(Date:7/31/2015)... Alexandria, VA (PRWEB) , ... July 31, 2015 ... ... Mesothelioma is a one-day event geared to patients and family members, medical professionals, ... local and regional mesothelioma experts. The conference is a collaborative effort between the ...
Breaking Medicine News(10 mins):Health News:Jvion Showcased as Leader in the Predictive Analytic Market 2Health News:King Kullen Honors National Hot Dog and Blueberry Month 2Health News:King Kullen Honors National Hot Dog and Blueberry Month 3Health News:MDLinx Offers Three New Board Exam Prep Courses - Gastroenterology, Pulmonology and Allergy/Immunology 2Health News:MDLinx Offers Three New Board Exam Prep Courses - Gastroenterology, Pulmonology and Allergy/Immunology 3Health News:Pastry Palace of Las Vegas Announces It Is Now Offering Custom Wedding Cakes in Las Vegas 2Health News:New York Area Mesothelioma Specialists to Present at Conference 2Health News:New York Area Mesothelioma Specialists to Present at Conference 3
... Device "Rewires" Brain, Improves and Restores Balance, Normal Walking , ... ... on, "virtual reality" has a whole new meaning for people with ... walk normally again., , , , ,The GaitAid Virtual Walker, a ...
... spring , , SATURDAY, May 16 (HealthDay News) -- Spring ... them, especially if you have asthma. , Pollen from ... trigger that sufferers must learn to cope with this ... Center at Brigham and Women,s Hospital in Boston. Other ...
... Women Find the Solutions to their Infertility Issues by Bridging the ... ... (PRWEB) May 16, 2009 -- National Fertility Link ... to be pregnant. National Fertility Link helps Infertile couples find the ...
... Dr. Gary L. Gottlieb, President of Brigham and Women,s ... Hill Community College,s 35th commencement exercises, on Saturday, ... proponent of alleviating mental health care disparities, will receive ... his outstanding commitment and service to the College. "Dr. ...
... (the "Company") today announced its operating results for the first ... Our net patient service revenue increased by $6.2 million, ... to $95.0 million from $88.8 million for the comparable period ... or 4.2%, less than the same period in 2008, while ...
... chances of macular degeneration , , FRIDAY, May 15 (HealthDay News) ... your eyes as well as the rest of your body, ... vitamins C and E, zinc, lutein, zeaxanthin, omega-3 fatty acids ... low-glycemic index foods) can lower the risk of developing age-related ...
Cached Medicine News:Health News:New Hope for Walking Normally, Living Better With Cerebral Palsy 2Health News:Know Your Asthma Triggers 2Health News:Fewer Than One Percent of Infertile Couples Who Need Treatment Receive It - Website to Bridge Gap Between Infertile Couples and Fertility Clinics 2Health News:Fewer Than One Percent of Infertile Couples Who Need Treatment Receive It - Website to Bridge Gap Between Infertile Couples and Fertility Clinics 3Health News:Healthcare Leader Dr. Gary Gottlieb Keynotes Commencement 2Health News:LifeCare Holdings, Inc. Announces First Quarter Results 2Health News:LifeCare Holdings, Inc. Announces First Quarter Results 3Health News:LifeCare Holdings, Inc. Announces First Quarter Results 4Health News:LifeCare Holdings, Inc. Announces First Quarter Results 5Health News:LifeCare Holdings, Inc. Announces First Quarter Results 6Health News:LifeCare Holdings, Inc. Announces First Quarter Results 7Health News:LifeCare Holdings, Inc. Announces First Quarter Results 8Health News:LifeCare Holdings, Inc. Announces First Quarter Results 9Health News:LifeCare Holdings, Inc. Announces First Quarter Results 10Health News:Nutrient-Rich Diet Lowers Risk of Age-Related Eye Disease 2
(Date:7/30/2015)...  Today we bring you a special edition of #MedicareMonday on Medicare,s 50 th ... of our Medicare resources and continue highlighting the success of the prescription drug benefit, ... Check out our latest infographics and videos here: http://onphr.ma/1INp9qQ ... ... ...
(Date:7/30/2015)... July 30, 2015 PTC Therapeutics, Inc. (NASDAQ: ... reported financial results for the second quarter ending June ... many fronts across the organization.  We are excited to ... dystrophy clinical trial ever conducted with topline results expected ... Chief Executive Officer, PTC Therapeutics, Inc. "Translarna is now ...
(Date:7/30/2015)... 30, 2015 Eisai Inc. announced today that ... United States , European Union and ... respectively) for eribulin, for the treatment of patients with ... chemotherapy for advanced or metastatic disease. ... pivotal global Phase 3 clinical trial (Study 309), which ...
Breaking Medicine Technology:Happy 50th Anniversary Medicare! 2Happy 50th Anniversary Medicare! 3PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 2PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 3PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 4PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 5PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 6PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 7PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 8PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 9PTC Therapeutics Reports Second Quarter 2015 Financial Results and Provides Corporate Update 10Eisai Submits Simultaneous Regulatory Applications for Eribulin in Soft Tissue Sarcoma in the United States, European Union and Japan 2Eisai Submits Simultaneous Regulatory Applications for Eribulin in Soft Tissue Sarcoma in the United States, European Union and Japan 3Eisai Submits Simultaneous Regulatory Applications for Eribulin in Soft Tissue Sarcoma in the United States, European Union and Japan 4Eisai Submits Simultaneous Regulatory Applications for Eribulin in Soft Tissue Sarcoma in the United States, European Union and Japan 5
... biopharmaceutical company at the forefront of immunology treatment and research, ... in Washington, D.C. by reinforcing its commitment to improving the ... meeting, a large body of UCB data will highlight the ... severe Crohn,s disease. "ACG is an opportunity for ...
... MILPITAS, Calif., Oct. 28, 2011 LifeScan, Inc., the maker ... with Rite Aid to launch the Rite Track ... of American Diabetes Month, a mobile bus will travel to ... to provide complimentary on-site blood glucose and A1c testing, educational ...
Cached Medicine Technology:UCB Proudly Reinforces Long-Standing Commitment to Patients and Physicians at American College of Gastroenterology 2011 Annual Scientific Meeting 2UCB Proudly Reinforces Long-Standing Commitment to Patients and Physicians at American College of Gastroenterology 2011 Annual Scientific Meeting 3Celebrity Chef Sam Talbot Gets on Board for Diabetes Testing 2Celebrity Chef Sam Talbot Gets on Board for Diabetes Testing 3Celebrity Chef Sam Talbot Gets on Board for Diabetes Testing 4
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: