Navigation Links
New advance in prostate cancer management

A new technique known as the Checkerboard Tissue Microarray (TMA) Method will markedly help in predicting the behaviour of prostate cancer.

Needle biopsies, blood and urine analysis are the current options available to determine how aggressive the cancer // is and whether it is likely to progress. The results of these tests are however not very accurate, resulting in thousands of men undergoing unnecessary surgery for prostate cancer.

The Checkerboard TMA Method looks for multiple markers of various genes associated with prostate cancer including the E2F3 gene. Over expression of the E2F3 gene is a marker of how aggressive the prostate cancer will be.

The technique will be pivotal in developing a test for prostate cancer aggressiveness which may ultimately prevent thousands of men undergoing unnecessary surgery, with its often associated severe side effects including incontinence and impotence.

Prostate cancer is now the most common cancer to affect men in the UK. More than 30,000 men in the UK are diagnosed with the disease and almost 10,000 men die from the disease each year.

The development of this gene-targeted approach towards prostate cancer has been made possible due to our improved understanding of the molecular mechanisms behind the disease. We still have a long way to go before such techniques can be used to improve the lives of millions of people afflicted with the disease.

For routine pathological examination, the needle biopsy samples are embedded in paraffin blocks to facilitate thin sectioning and examination. The new method requires the biopsies to be cut into cubes, which are oriented in an appropriate way to expose a cross-section of the sample. These reoriented samples are then re-embedded in hot paraffin wax followed by slicing and staining. Samples processed this way retain the antigenicity, which makes it ideal to be tested for tumour progression.

The Institute o f Cancer Research was founded in 1909 to carry out research into causes of cancer. The institute aims at developing new strategies for prevention, diagnosis and treatment Of cancer. The institute has proved it yet another time its commitment towards the cause of cancer by developing this novel technique.

It is appropriate to remember that E2F3 gene (marker gene), BRCA2 gene (determine predisposition to prostate cancer and breast cancer) has been identified and sequenced by the members of the institute. In addition, the institute has also developed 'conformal radiotherapy' which allows higher doses of radiation to be targeted directly at tumors.


'"/>




Related medicine news :

1. The negative advancement
2. Innovative device aids in advanced heart failure
3. Light therapy devotes new hope in advanced lung cancer
4. Race an important links to the risk of advanced colorectal cancer
5. Radiology advance points way to non-invasive brain cancer treatment
6. NICE supports application of advanced biological therapies as treatment option for acute psoriasis
7. Better prostate cancer detection
8. Protective effects of tomatoes in prostate cancer
9. Early detection of prostate cancer
10. Fingerprinting prostate cancer
11. No link between blood groups and prostate cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... ... established the certification process to promote standards of excellence for the field of ... scheduled for March 22 – 25, 2018 in Orlando, Florida at the Omni ...
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term insurance ... care insurance companies have a waiver for care if the client has a cognitive ... the family pays for care, is often waived, so the benefits from their insurance ...
(Date:10/13/2017)... ... October 13, 2017 , ... Talented host, actor Rob Lowe, ... in a new episode of "Success Files," which is an award-winning educational program ... investigates each subject in-depth with passion and integrity. , Sciatica occurs when the ...
(Date:10/12/2017)... ... October 12, 2017 , ... CitiDent and ... apnea using cutting-edge Oventus O2Vent technology. As many as 18 million Americans ... frequent cessation in breathing. Oral appliances can offer significant relief to about 75 ...
(Date:10/12/2017)... ... October 12, 2017 , ... Asante, a nationally recognized ... have expanded their existing home health joint venture through an agreement, effective October ... a joint venture home health company with Asante, delivering clinically integrated care, for ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... , Sept. 25, 2017  EpiVax, Inc., a ... design, and immune-engineering today announced the launch of ... development of personalized therapeutic cancer vaccines. EpiVax has ... exclusive access to enabling technologies to the new ... will lead EpiVax Oncology as Chief Executive Officer. ...
(Date:9/19/2017)... Mich. , Sept. 19, 2017 HistoSonics, Inc., a venture-backed medical device company ... destruction of targeted tissues, announced three leadership team developments today:   ... PhD ... ... Veteran medical device executive Josh ...
(Date:9/13/2017)... 13, 2017   OrthoAtlanta has been named the ... Host Committee (AFHC) for the 2018 College Football Playoff (CFP) ... at Mercedes-Benz Stadium in Atlanta, Georgia . ... "I,m In" campaign, participating in many activities leading up to, ... ...
Breaking Medicine Technology: