Navigation Links
New advance in prostate cancer management

A new technique known as the Checkerboard Tissue Microarray (TMA) Method will markedly help in predicting the behaviour of prostate cancer.

Needle biopsies, blood and urine analysis are the current options available to determine how aggressive the cancer // is and whether it is likely to progress. The results of these tests are however not very accurate, resulting in thousands of men undergoing unnecessary surgery for prostate cancer.

The Checkerboard TMA Method looks for multiple markers of various genes associated with prostate cancer including the E2F3 gene. Over expression of the E2F3 gene is a marker of how aggressive the prostate cancer will be.

The technique will be pivotal in developing a test for prostate cancer aggressiveness which may ultimately prevent thousands of men undergoing unnecessary surgery, with its often associated severe side effects including incontinence and impotence.

Prostate cancer is now the most common cancer to affect men in the UK. More than 30,000 men in the UK are diagnosed with the disease and almost 10,000 men die from the disease each year.

The development of this gene-targeted approach towards prostate cancer has been made possible due to our improved understanding of the molecular mechanisms behind the disease. We still have a long way to go before such techniques can be used to improve the lives of millions of people afflicted with the disease.

For routine pathological examination, the needle biopsy samples are embedded in paraffin blocks to facilitate thin sectioning and examination. The new method requires the biopsies to be cut into cubes, which are oriented in an appropriate way to expose a cross-section of the sample. These reoriented samples are then re-embedded in hot paraffin wax followed by slicing and staining. Samples processed this way retain the antigenicity, which makes it ideal to be tested for tumour progression.

The Institute o f Cancer Research was founded in 1909 to carry out research into causes of cancer. The institute aims at developing new strategies for prevention, diagnosis and treatment Of cancer. The institute has proved it yet another time its commitment towards the cause of cancer by developing this novel technique.

It is appropriate to remember that E2F3 gene (marker gene), BRCA2 gene (determine predisposition to prostate cancer and breast cancer) has been identified and sequenced by the members of the institute. In addition, the institute has also developed 'conformal radiotherapy' which allows higher doses of radiation to be targeted directly at tumors.


'"/>




Related medicine news :

1. The negative advancement
2. Innovative device aids in advanced heart failure
3. Light therapy devotes new hope in advanced lung cancer
4. Race an important links to the risk of advanced colorectal cancer
5. Radiology advance points way to non-invasive brain cancer treatment
6. NICE supports application of advanced biological therapies as treatment option for acute psoriasis
7. Better prostate cancer detection
8. Protective effects of tomatoes in prostate cancer
9. Early detection of prostate cancer
10. Fingerprinting prostate cancer
11. No link between blood groups and prostate cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/23/2017)... ... ... 150+ Hospital and Health System Executive Speakers including: , , Chief ... the United States of America: George W. Bush , Boxing Legend, Successful Entrepreneur ... Leonard , JD, Chairperson, McGuireWoods LLP: Amber McGraw Walsh , Senior ...
(Date:3/23/2017)... Grants Pass, OR (PRWEB) , ... March 23, 2017 , ... ... Power of Water, Global Climate Change and Your Health on VoiceAmerica, recently talked on ... 22nd, but she also used the occasion to remind listeners of an important distinction. ...
(Date:3/23/2017)... ... March 23, 2017 , ... Natural ... all aspects of people’s health and nutrition, announced its product Leyzene is now ... Natural Subsistence develops nutritional supplements that help people improve all aspects of their ...
(Date:3/23/2017)... ... ... Inflow IQ & Inflownomics of Raleigh, NC introduce a powerful information access network. ... experts in dangerous situations the Inflow IQ team can help people. Get ready ... & refreshing knowledge systems that enhance life. , Authentically enjoy 500 ...
(Date:3/23/2017)... ... , ... The American Board of Quality Assurance and Utilization Review Physicians (ABQAURP) ... Health Care Quality and Management and Patient Safety. , It is with appreciation and ... also to the Health Care Quality and Patient Safety movements. Diplomates and Members lead ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... 23, 2017  Additive Orthopaedics, LLC., an early ... has kicked off a multi-centered clinical study to ... segments. According to Brian McLaughlin ... lattice structures have already shown tremendous post-operative success ... allograft wedges from which we have seen evidence ...
(Date:3/23/2017)... 23, 2017 Newborns are highly vulnerable ... vaccines because their young immune systems typically mount ... Hospital report achieving strong vaccine responses in newborn ... before human trials — by adding compounds known ... two simultaneous papers, they also describe improved adjuvant ...
(Date:3/23/2017)...  A new genetic test has been discovered ... who carry HLA-B*15:02 and who are ... deadly side effect of certain medications used to ... HLA-B*15:02 is strongly associated with life-threatening severe ... toxic epidermal necrolysis in patients treated with carbamazepine ...
Breaking Medicine Technology: