Navigation Links
New advance in prostate cancer management

A new technique known as the Checkerboard Tissue Microarray (TMA) Method will markedly help in predicting the behaviour of prostate cancer.

Needle biopsies, blood and urine analysis are the current options available to determine how aggressive the cancer // is and whether it is likely to progress. The results of these tests are however not very accurate, resulting in thousands of men undergoing unnecessary surgery for prostate cancer.

The Checkerboard TMA Method looks for multiple markers of various genes associated with prostate cancer including the E2F3 gene. Over expression of the E2F3 gene is a marker of how aggressive the prostate cancer will be.

The technique will be pivotal in developing a test for prostate cancer aggressiveness which may ultimately prevent thousands of men undergoing unnecessary surgery, with its often associated severe side effects including incontinence and impotence.

Prostate cancer is now the most common cancer to affect men in the UK. More than 30,000 men in the UK are diagnosed with the disease and almost 10,000 men die from the disease each year.

The development of this gene-targeted approach towards prostate cancer has been made possible due to our improved understanding of the molecular mechanisms behind the disease. We still have a long way to go before such techniques can be used to improve the lives of millions of people afflicted with the disease.

For routine pathological examination, the needle biopsy samples are embedded in paraffin blocks to facilitate thin sectioning and examination. The new method requires the biopsies to be cut into cubes, which are oriented in an appropriate way to expose a cross-section of the sample. These reoriented samples are then re-embedded in hot paraffin wax followed by slicing and staining. Samples processed this way retain the antigenicity, which makes it ideal to be tested for tumour progression.

The Institute o f Cancer Research was founded in 1909 to carry out research into causes of cancer. The institute aims at developing new strategies for prevention, diagnosis and treatment Of cancer. The institute has proved it yet another time its commitment towards the cause of cancer by developing this novel technique.

It is appropriate to remember that E2F3 gene (marker gene), BRCA2 gene (determine predisposition to prostate cancer and breast cancer) has been identified and sequenced by the members of the institute. In addition, the institute has also developed 'conformal radiotherapy' which allows higher doses of radiation to be targeted directly at tumors.


'"/>




Related medicine news :

1. The negative advancement
2. Innovative device aids in advanced heart failure
3. Light therapy devotes new hope in advanced lung cancer
4. Race an important links to the risk of advanced colorectal cancer
5. Radiology advance points way to non-invasive brain cancer treatment
6. NICE supports application of advanced biological therapies as treatment option for acute psoriasis
7. Better prostate cancer detection
8. Protective effects of tomatoes in prostate cancer
9. Early detection of prostate cancer
10. Fingerprinting prostate cancer
11. No link between blood groups and prostate cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/3/2016)... ... 03, 2016 , ... The new web-based solution HIPAA ... practices, to better grasp and implement HIPAA’s privacy, security, and data breach requirements. ... well-defined, expert-created path to compliance. HIPAA Institute has positioned itself to be an ...
(Date:5/2/2016)... ... May 03, 2016 , ... RNK ... sSOIP telemedicine stethoscope software that enables the stethoscope stream to go over the ... works with RNK’s flagship PCP-USB stethoscope. , Remote auscultation involves two software elements ...
(Date:5/2/2016)... ... May 02, 2016 , ... The Beryl Institute announces ... (PXJ), an international, open access, peer-reviewed journal focused on research and proven practices ... (non-US) based authors, the third volume of PXJ continues to expand PXJ's reach ...
(Date:5/2/2016)... ... May 02, 2016 , ... The Civilian Corps of the ... the civilian nurses that care for its uniformed service members, the retired service members, ... 1974 designating May 6th through May 12th National Nurses Week. It acknowledges the hard ...
(Date:5/2/2016)... WACO, Texas (PRWEB) , ... May 02, 2016 , ... ... Corporation will offer an incentive to people who share their fitness journey on ... footwear and premium first aid products, will award a $100 product voucher each week ...
Breaking Medicine News(10 mins):
(Date:5/2/2016)... May 2, 2016 Kalorama Information noted the ... Records) market in a recent white paper.  The healthcare ... physician usage, a growing market are among the top ... Kalorama,s report EMR 2016: The Market for ... seventh complete study of the EMR industry, and the ...
(Date:5/2/2016)... , May 2, 2016  Deerfield announced ... financing of Graybug Vision, Inc. Graybug Vision is ... therapies that may transform care for ocular diseases ... Graybug Vision,s technology was first developed at Johns ... a startup venture. Graybug Vision ...
(Date:5/2/2016)... , May 2, 2016  Celsion Corporation (NASDAQ: ... today announced data from the first cohort of ... trial (the OVATION Study) combining GEN-1, the Company,s ... the treatment of newly-diagnosed patients with advanced ovarian ... interval debulking surgery.  In the first three patients ...
Breaking Medicine Technology: