Navigation Links
New advance in prostate cancer management

A new technique known as the Checkerboard Tissue Microarray (TMA) Method will markedly help in predicting the behaviour of prostate cancer.

Needle biopsies, blood and urine analysis are the current options available to determine how aggressive the cancer // is and whether it is likely to progress. The results of these tests are however not very accurate, resulting in thousands of men undergoing unnecessary surgery for prostate cancer.

The Checkerboard TMA Method looks for multiple markers of various genes associated with prostate cancer including the E2F3 gene. Over expression of the E2F3 gene is a marker of how aggressive the prostate cancer will be.

The technique will be pivotal in developing a test for prostate cancer aggressiveness which may ultimately prevent thousands of men undergoing unnecessary surgery, with its often associated severe side effects including incontinence and impotence.

Prostate cancer is now the most common cancer to affect men in the UK. More than 30,000 men in the UK are diagnosed with the disease and almost 10,000 men die from the disease each year.

The development of this gene-targeted approach towards prostate cancer has been made possible due to our improved understanding of the molecular mechanisms behind the disease. We still have a long way to go before such techniques can be used to improve the lives of millions of people afflicted with the disease.

For routine pathological examination, the needle biopsy samples are embedded in paraffin blocks to facilitate thin sectioning and examination. The new method requires the biopsies to be cut into cubes, which are oriented in an appropriate way to expose a cross-section of the sample. These reoriented samples are then re-embedded in hot paraffin wax followed by slicing and staining. Samples processed this way retain the antigenicity, which makes it ideal to be tested for tumour progression.

The Institute o f Cancer Research was founded in 1909 to carry out research into causes of cancer. The institute aims at developing new strategies for prevention, diagnosis and treatment Of cancer. The institute has proved it yet another time its commitment towards the cause of cancer by developing this novel technique.

It is appropriate to remember that E2F3 gene (marker gene), BRCA2 gene (determine predisposition to prostate cancer and breast cancer) has been identified and sequenced by the members of the institute. In addition, the institute has also developed 'conformal radiotherapy' which allows higher doses of radiation to be targeted directly at tumors.


'"/>




Related medicine news :

1. The negative advancement
2. Innovative device aids in advanced heart failure
3. Light therapy devotes new hope in advanced lung cancer
4. Race an important links to the risk of advanced colorectal cancer
5. Radiology advance points way to non-invasive brain cancer treatment
6. NICE supports application of advanced biological therapies as treatment option for acute psoriasis
7. Better prostate cancer detection
8. Protective effects of tomatoes in prostate cancer
9. Early detection of prostate cancer
10. Fingerprinting prostate cancer
11. No link between blood groups and prostate cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/15/2017)... ... January 15, 2017 , ... Going above and beyond the ... to better communities around the world by offering the Gensuite team and their ... for team members to become involved in a cause that is bigger than ...
(Date:1/15/2017)... ... January 15, 2017 , ... Accreditation Commission for ... for its specialty care services. Albertsons Companies is the largest national food ... for pharmacy patients. , Accreditation by ACHC reflects Albertsons Companies’ dedication and commitment ...
(Date:1/15/2017)... ... January 15, 2017 , ... ... best physicians in eight Bay Area counties for 2017. Almost 1,000 nominations were ... company managing the award process. Results were announced the magazine’s January 2017 ...
(Date:1/15/2017)... ... January 15, 2017 , ... The Gravity Vault Indoor Rock Climbing Gym ... construction wraps up on the 14,000+ square foot climbing gym, the owners anticipate to ... three in New Jersey and two in New York. With this being its first ...
(Date:1/14/2017)... MN (PRWEB) , ... January 14, 2017 , ... ... present the distinctions among their expanding line of activated charcoal products. With more ... the importance of categorizing their products according to how they cater to specific ...
Breaking Medicine News(10 mins):
(Date:1/16/2017)... 16, 2017  According to Kalorama Information, the ... valued at $4.9 billion for 2016.  The growing ... an aging population with significant diagnostic needs, along ... propelling the market for the modality.  The healthcare ... , focuses on the worldwide market, providing market ...
(Date:1/16/2017)... , January 16, 2017 ... Derivatives Market by Product Type (Methyl, Ethyl, Hydroxyethyl, ... Foods & Beverages, Surface Coatings & Paints), ... by MarketsandMarkets, the market was valued at ... projected to reach USD 6.41 Billion by ...
(Date:1/16/2017)... CRUZ, Calif. , Jan. 16, 2017  Dovetail ... Dovetail™ Hi-C sequencing and assembly service, which yields chromosome-scale ... be presented in a Dovetail-hosted workshop on Jan. 17 ... in San Diego . ... services with the launch of our Dovetail Hi-C offering," ...
Breaking Medicine Technology: