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New Treatment For Psoriasis Is Highly Effective

th risk of both psoriasis and IBD, while the uncommon forms are protective, according to Krueger.

'This is really an alignment of the stars. It’s unusual that targeting a new inflammatory pathway in two different diseases provides patients with dramatic improvement,' he said. 'And then, almost simultaneously, we find disease-associated genetic variants in this same pathway.'

Krueger and colleagues at Celera predict that refinement of disease association patterns to specific genetic variants within IL-12/23 and the IL-23 receptor will play an important role in the elucidation of the causes of psoriasis, and IBD.

Krueger says that, 'Further studies should help determine whether any of the identified differential risk polymorphisms are also associated with response to therapy and possible toxicities and thereby help determine the most effective dosage of these new monoclonal antibody therapies.'

Source-Newswise
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