Navigation Links
New Tests Promise Rapid and Accurate Detection of Malaria

Rapid diagnostic tests, or RDTs, are becoming an increasingly important method for detecting malaria. Health specialists recommend that they be used along with a range of other strategies for controlling the disease // , including the use of artemisinin-based combination therapies, insecticide-treated bed nets, indoor spraying against malaria-carrying mosquitoes and testing and treatment of pregnant women and children.

The tests are ideal for rural areas are accurate, easy to use and at less than one dollar per test, inexpensive. Prior to RDTs, blood samples had to be sent to labs to be examined under a microscope. Not now. With the prick of a finger, the RDTs can detect in less than 10 minutes the most common and deadly malaria parasite in the tropics, Plasmodum falciparum.

Dr. Trenten Ruebush is a senior malaria advisor at USAID in Washington.

The major reason everyone is interested in RDTs, he adds, "is that [the cost] of the new combination malaria drugs introduced throughout Africa and other countries are 10 to 20 times higher than the former single drug therapies like chloroquine and amodiaquine. It’s critical to have accurate diagnosis to ensure those expensive drugs are being used in those who are infected and do need them. You don’t want to use those expensive drugs in someone who has a fever due to another cause.

But health specialists say some field technicians continue to prescribe expensive anti-malarials despite a negative reading by the RDTs.

Ruebush says, “whether a clinician or health worker in a rural health clinic will pay attention to the results of a microscopic examination of the blood or of an RDT is another matter. It does happen more often than it should that when the results of the diagnostic tests don’t agree with what the health worker believes to be the case, the health worker will often give the treatment anyway. And then, yes, it does defeat the purpose of the tests, but as RPTs are being scaled up in Africa, efforts are being made to educate health workers about the appropriate use of the test and the patient to know that a negative test from an RDT means you do not have malaria. It does not mean you are not ill. It just means you do not have malaria."

Rima Shretta is a senior program associate for Management Sciences for Health in Arlington, Virginia. She says her group is interested in collecting data on the way African health workers use the tests. However, she notes that the World Health Organization recommends that one group does not need to be treated with RDTs, but can be treated with just a clinical diagnosis: children under five living in high malaria transmission areas with symptoms such as fever. She says they are among the most vulnerable to the disease and that it’s very likely that malaria is the cause of their current fever. For that reason, she says it’s not cost effective to spend the money on rapid diagnostic tests.

The mortality rate for children under five is high," she says, "and [there is the] likelihood [that these children’s] have malaria if their fever is quite high. [There is a probability that they will have malaria which may progress very rapidly to severe disease in the absence of treatment due to low levels of immunity]. In areas with no RDTs what they recommend is that clinical diagnosis [based on observed symptoms] -- which had been the cornerstone for children under five -- continue to be used as opposed to RDTs because there is a high likelihood they will have malaria anyway. Guidelines on the integrated management of childhood illnesses (imci) recommend that fever be used as a proxy for malaria.

Shretta says her organization is also assessing the supply chain to ensure the quality of the test kits, which must be stored in temperatures lower than 30 degrees Celsius to maintain their accuracy and reliability. Meanwhile, the WHO is compiling data that hel p donors and other buyers assess the quality of the 40 or so tests now on the market.

Source: Bio-Bio-technology


Related medicine news :

1. The Effectiveness Of Screening Tests Questioned
2. Blood Tests Can Help Detect Osteoporosis Early In Life
3. Easier Tests To Detect Tuberculosis
4. Fragile X-Associated Tremor /Ataxia Syndrome Need Guidelines For Diagnostic Tests
5. Genetic Tests Could Become As Affordable As Blood Tests
6. Obese Adults Undergo Less Medical Tests And More Vulnerable To Diseases
7. Delay in Breast Cancer Gene Tests
8. Health Officials Inquire Into OraQuick HIV Tests
9. Move to make HIV Tests mandatory For Soldiers In Northeast
10. Punjab Government To Clamp Down On Sex Determination Tests
11. Free HIV Tests Brings Crowd to the Testing Centers
Post Your Comments:

(Date:12/1/2015)... ... December 01, 2015 , ... Trustify is proud to announce the success ... Becky’s Fund, an organization dedicated to ending domestic violence. , Trustify and Becky’s Fund ... victims and survivors of domestic violence. Trustify is also proud to announce the launch ...
(Date:12/1/2015)... ... December 01, 2015 , ... World Patent Marketing , ... a container patent that allows for easier packing and organizing of items into one ... $90 billion," says Scott Cooper, CEO and Creative Director of World Patent Marketing and ...
(Date:12/1/2015)... ... December 01, 2015 , ... Integrated Rental Services ... Jordan Industries International, LLC (“JII”). , With support from JII, Integrated Rental is ... to hospitals, surgery centers, clinics, research labs and medical facilities across the United ...
(Date:12/1/2015)... (PRWEB) , ... December 01, 2015 , ... ... of leadless pacemakers in the U.S. and is the only hospital in the ... the largest clinical data presentation of transcatheter pacing patients were revealed recently at ...
(Date:12/1/2015)... ... December 01, 2015 , ... Growth in medical payments per workers’ compensation claim ... of hospital and nonhospital care, according to a recent study by the Workers Compensation ... Edition , found medical payments per claim with more than seven days of lost ...
Breaking Medicine News(10 mins):
(Date:12/1/2015)... 1, 2015 --> ... Drugs Market by Type of Drug (Monoclonal Antibodies, Interferon-Alpha, Interleukins, ... and Pipeline Analysis - Global Forecast to 2020", published by ... USD 73,529.2 Million by 2020 from USD 40,281.6 Million in ... Browse 37 market data ...
(Date:12/1/2015)... BANGALORE, India and ... (NASDAQ, TASE: MYL) today announced that it expects to ... for developing country markets funded by international donors, TLE400 ... + Efavirenz 400 mg) for $99 per patient, per ... (CHAI) to develop TLE400. The significantly reduced price could ...
(Date:12/1/2015)... 1, 2015  AccuTEC Blades, a leader in ... logo and brand identity program. The new logo ... of bladed products where "the edge makes all ... --> Serving manufacturers and distributors of medical, ... equipment, AccuTEC,s product lines include those acquired when ...
Breaking Medicine Technology: