Navigation Links
New Strategy Identified for Preventing Acute and Chronic Brain Disease

prevented when one or both copies of the tau gene were eliminated.

Tau is made normally by brain cells and regulates the stability of their internal skeleton. In AD, tau is altered in a way that makes it aggregate into clumps, called tangles. A lot of effort has been devoted to finding ways to specifically eliminate these abnormal forms of tau, but this has been difficult. The current study suggests that lowering overall tau levels may be a good alterative, especially since even partial tau reduction was effective and very well tolerated, at least in the mice.

A breakthrough came when the researchers identified a mechanism by which tau reduction could protect the brain. They found that tau reduction protects brain cells against overstimulation, which can interfere with the brain's normal functioning and even cause seizures. Indeed, mice with reduced levels of tau were also resistant against epileptic seizures.

"This connection between tau and neuronal overexcitation was really unexpected," said Dr. Roberson. "It opens up totally new ways of thinking about tau and its involvement in neurological disease."

Because overstimulation of brain cells contributes to a variety of major neurological diseases, these findings may have broad therapeutic implications.

"We still have hurdles to cross before this discovery is translated into something that is ready for patients," said Dr. Mucke. "But there is an urgent need for better treatments in this field, so it is really exciting to have identified such a promising approach."


'"/>




Page: 1 2

Related medicine news :

1. Novel Strategy To Combat Alzheimer’s Disease
2. "Defensive Pessimism" Before Exam Results Not a Good Strategy
3. WHO Devises New Global Strategy To Fight Tuberculosis
4. HER-2 Positive Breast Cancer Patients May Benefit With a Combo Drug Strategy
5. West Nile Virus Can Be Tackled By New Strategy
6. Australia Set To Implement A national Strategy Tackle Cannabis Abuse
7. Clement Urged to Plot a National Pharmaceutical Strategy
8. New Preventive Strategy to Fight Childhood Obesity
9. Rae unveils Health-care Strategy
10. A Promising New Vaccination Strategy for Late-Stage Melanoma
11. Effective Strategy Against Bird flu-Spainish Flu Vaccine Raises Hopes
Post Your Comments:
(Date:8/28/2015)... ... 2015 , ... Medical Solutions, one of the nation’s largest travel nurse staffing ... by Modern Healthcare and will be honored at an awards dinner in Chicago ... Best Places to Work in Healthcare program recognizes outstanding employers in the healthcare industry ...
(Date:8/28/2015)... ... 28, 2015 , ... The Nashville Business Journal recently announced ... business. Mr. Troy Mizell, Chairman of the Board at MyGenetx, is one ... Veterans Awards will recognize Nashville military veterans who, through their professional and personal ...
(Date:8/28/2015)... ... 28, 2015 , ... CARF International announced that West Ridge ... treatment and intensive family based services. , By pursuing and achieving accreditation, West ... of excellence. As a nonprofit charity for more than 50 years, West Ridge ...
(Date:8/28/2015)... ... , ... Dr. Gregory K. Toumayan, D.C., Q.M.E., is now treating patients with ... pain, hip pain, neck pain, stiffness, muscle spasms, and numbness. , Dr. Toumayan ... then went on to earn his title of Doctor of Chiropractic from the Palmer ...
(Date:8/28/2015)... ... August 28, 2015 , ... SmartPractice Calendars afford ... with practice contact information and logos, Calendars stand alone as functional brand-building ... into seasonal mailings, thank you and welcome communications, and to complement statements and ...
Breaking Medicine News(10 mins):Health News:Medical Solutions Recognized as One of 2015 Best Places to Work in Healthcare 2Health News:Medical Solutions Recognized as One of 2015 Best Places to Work in Healthcare 3Health News:MyGenetx Board Member Receives Veterans Award 2Health News:West Ridge Academy Awarded CARF Three-Year Accrediation 2Health News:Healthpointe Welcomes Dr. Gregory K. Toumayan, Chiropractor, to Colton, Temecula, and Perris 2Health News:Healthpointe Welcomes Dr. Gregory K. Toumayan, Chiropractor, to Colton, Temecula, and Perris 3Health News:SmartPractice® Introduces 2016 Calendars for Dental Practice Giveaways 2
... fossil teeth has thrown new light on the recent origin ... beings apart from their primate ancestors, according to an article ... of the fossil teeth, researchers from University College, London and ... 25 year development period of humans compared with 11 or ...
... Increasing folic acid intake and decreasing alcohol help beat the ... According to previous studies have shown that colon cancer often ... with the disease, you can opt for regular colon exams, ... and vegetables to reduce your cancer risk. ,According ...
... art is regnant among undergraduate university students, and there ... piercing,"// said Dr. Lester B. Mayers of the Pace ... lead author of the study. ,A survey ... had some type of body piercing and 22 percent ...
... ,According to researchers at the Hopkins Heart Institute, a blunt and ... When it comes to accidents and sports injuries,// it is a ... at the a blow to the chest may prove more hazardous. ... type of cardiac arrest called commotio cordis, which occurred after a ...
... dangerous parasitic disease from their new organs in the ... one recovered after antibiotic treatment.// A second study also ... turned up 26 bacterial infections traced to tissue grafts ... ,This shows that the graft-related infections show an ...
... prototype handheld detector under development at Sandia National Laboratories ... anthrax in less than five minutes. //Sandia's Laboratory Directed ... a multiprogram laboratory operated by Sandia Corporation, a Lockheed ... ,Fatty acids are found in all living organisms with ...
Cached Medicine News:
(Date:8/27/2015)... 27, 2015  The Academy of Managed Care ... Administration,s (FDA,s) draft guidance and proposed rule that ... to bear a nonproprietary name with an FDA-designated ... a decision from the FDA on the naming ... stakeholders urging the agency to use the same ...
(Date:8/27/2015)... , Aug. 27, 2015 ieCrowd™ ... in the commercial development of the company,s supplemental ... Smart Oxygen device, being developed by ieCrowd,s subsidiary ... a patient,s changing demand for oxygen based on ... 510 (k) submission for the Smart Oxygen device ...
(Date:8/27/2015)...   Women Grow , the fastest-growing professional networking organization ... the Cannabis World Congress & Business Exposition (CWCBExpo) ... business-focused educational sessions. CWCBExpo in LA will take place September ... Convention Center in Los Angeles, CA , ... for the marijuana industry. The Women Grow tracks ...
Breaking Medicine Technology:AMCP Is Disappointed in FDA's Draft Guidance and Proposed Rule Calling for Suffix on Nonproprietary Names of Biological Products 2Smart Oxygen Solutions' Supplemental Oxygen Delivery Device Achieves FDA Regulatory Pathway Milestone 2Smart Oxygen Solutions' Supplemental Oxygen Delivery Device Achieves FDA Regulatory Pathway Milestone 3Smart Oxygen Solutions' Supplemental Oxygen Delivery Device Achieves FDA Regulatory Pathway Milestone 4Cannabis World Congress in Los Angeles Boasts Women Grow Sponsored Education 2Cannabis World Congress in Los Angeles Boasts Women Grow Sponsored Education 3Cannabis World Congress in Los Angeles Boasts Women Grow Sponsored Education 4
5mSports™ is the handheld version of 5 Minute Sports Medicine Consult, your favorite reference for on-field and off-field treatment of sports related problems....
... involved with healthcare decisions to keep up ... in their field of interest - a ... the volume of evidence increases. Cochrane Reviews ... single source available for continually updated evidence-based ...
... information that every intern needs from ... the neurologic history and physical examination, ... and diagnostic tools, and clinical information ... ataxia, acute vision loss, headache, movement ...
... an all-original guide prepared specifically ... Derived from "PocketMedicine/Internal Medicine", it ... to those training in the ... who are frequently the first ...
Medicine Products: