Navigation Links
New Stem Cells lines will be required

According to experts, existing stem cell lines could aggregate genetic abnormalities over time and new stem cell lines will likely be needed. According to Dr.Vogelstein, chairman of a key stem cell research committee of the National Research Council and Institute of Medicine, the current stem cell lines are problematic because they accumulate mutations as they grow.// Every time a cell divide in a tissue culture it accumulates mutations. In aggregate those mutations may cause certain problems.

Vogelstein and other medical experts justified before a Senate appropriations subcommittee. Stem cells are unspecialized cells that can become any cell type with specialized functions. They can be gleaned from several sources, such as placenta, umbilical cords and adult cells, but scientists say those originated from human embryos are most useful for therapeutic and research applications.

Stem cells, if implanted in a patient, could multiply cells afresh, offering cures for intractable diseases like Parkinson's disease, Alzheimer's and diabetes. But that decision permits federal funding only on the some 50 existing stem cell lines that have already been derived.

While stem cell providers the world over are looking to the National Institutes of Health to fund stem cell research on those existing lines, experts like Vogelstein warn of problems. One issues is that many of the existing lines were "cultured with animal cells and serum" creating the fear that pathogens in mice or cows could be transmitted to humans if the stem cells are used for therapeutic applications.

Another problem is that patient's immune system may attack the newly introduced stem cells. One way of sidestepping the problem is through a process known as somatic cell nuclear transfer or SCNT. That procedure, also known as therapeutic cloning, involves taking DNA from a cell belonging to a patient and inserting it into an egg whose nucleus has been removed. When the cell divides, it produces stem cells that can be put in the patient without causing an immune response.

But some lawmakers would like to see so-called therapeutic cloning -- which, unlike reproductive cloning, will never result in a birth -- outlawed. A proposed measure by Sen. Sam Brownback, R-Kan., would outlaw the act of therapeutically cloning a human embryo. It would also ban the importation of products derived from therapeutic cloning.

Vogelstein said such a ban could mean that "regenerative medical applications will never occur and people with terrible diseases won't be healed." He also said that since much biomedical research is international, "it's likely most useful lines and reagents will be developed outside the U.S." Therefore, a ban on importation would also curtail important research.


'"/>




Related medicine news :

1. Blood Cells Capable of Regenerating Liver
2. White Cells Count Can Predict Heart Attack Death Risk
3. Gene Therapy Destroys Pancreatic Cancer Cells
4. Stem Cells Have Few Mutations
5. Heart may pull Cells from Body to Self-repair
6. Cells critical for asthma development found
7. Vitamin D Wipes out Cancer Cells
8. Bone Marrow Cells Help Heart Attack Patients
9. Islet Cells May Lead to Diabetes CureChildren
10. Stem Cells Found To Offer Promise For Hair Growth
11. Bone Marrow Cells Could Yield A New Lease of Life
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/26/2017)... ... 2017 , ... RawTrition now brings you BioEnergy which is a powder capsule ... , RawTrition is taking nutrients to the next level! The superfoods in ... raw form (unlike the synthetically made options that are on the market). , Founder ...
(Date:4/25/2017)... ... April 25, 2017 , ... ... cream that’s the first in a new class of photodynamic cosmetics (PDC). , ... of skin, visibly reduce outward signs of aging, and minimize the appearance of ...
(Date:4/25/2017)... (PRWEB) , ... April 25, 2017 , ... ... CEOs, CFOs and HR decision-makers are preparing for how his administration could impact ... will provide insight into what changes are most likely to make it through ...
(Date:4/25/2017)... (PRWEB) , ... April 25, 2017 , ... ... targets, they rely on contracted partners to help with process innovation in drug ... combined drug formulation experience along with state-of-the-art analytical equipment in support of their ...
(Date:4/25/2017)... , ... April 25, 2017 , ... ... of predictive analytics to its patient care management module. Using this new feature, ... a patient has been initiated on continuous positive airway pressure (CPAP), oral, or ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... NEW YORK , April 19, 2017 /PRNewswire/ ... This report on the prostate cancer ... of the global market. Increasing prevalence of prostate ... as innovation in the development of new drugs ... hormone-refractory prostate cancer drug due to lesser side ...
(Date:4/19/2017)... April 19, 2017  Sorrento Therapeutics, Inc. (NASDAQ: ... biopharmaceutical company developing new treatments for cancer and ... of its previously announced underwritten public offering of ... public offering price of $2.00 per share, before ... expenses payable by Sorrento.  The net proceeds to ...
(Date:4/19/2017)... April 19, 2017  Novartis today announced the ... Heart, Lung, and Blood Institute (NHLBI) of the ... of patients with treatment-naïve severe aplastic anemia (SAA) ... with eltrombopag at the initiation of and concurrently ... evaluated three sequential treatment groups, or cohorts. Cohort ...
Breaking Medicine Technology: