Navigation Links
New Sleep Gene Discovery Wakes Up Scientists

rger said. "They were able to adjust but the price they have to pay is their body wakes up early, and they have to go to bed earlier than we do."

"The theory was that the mutation caused (more of the PERIOD protein) so you get a short day so you want to get up very early in the morning," Forger said. But, during testing they found the opposite is true: the mutation actually caused the PERIOD to degrade more quickly so that less is present in the body.

The finding wasn't a complete surprise to Forger, who develops math models of the circadian rhythms. Forger's computer models always said that the opposite of the prevailing thinking should be true---that the PERIOD protein should degrade more quickly when the mutation is present.

"I had this prediction for a year or two," Forger said. "Basically, people said this is ridiculous, you're a mathematician, what do you know…"

Then he met David Virshup, M.D., while giving an invited talk at the University of Utah. Virshup's previous research was on the gene involved in circadian rhythms and its role in cancer development. Their experiments had also suggested that genetic mutation caused the protein to degrade more quickly. Virshup suggested they test Forger's simulation.

The researchers took cell cultures and observed that for those with the mutated gene, the protein only took a couple hours to degrade. For the normal gene, it took 8-10 hours.

Next, Virshup said, his team will begin testing ways to regulate the circadian rhythm in mice, a necessary step before new drugs can be developed.

(Source: Newswise)
'"/>




Page: 1 2

Related medicine news :

1. Sleep apnoea increases post-operative risks
2. Sleep, snoring....stroke
3. Sleeping sickness - a silent killer
4. Deep Sleep Doesnt Increase Memory
5. Sleepwalking has genetic roots
6. Sleepy drivers increase road death toll
7. Sleep apnoea linked to surgical risks
8. Sleep disorders can have anomalistic sexual acts
9. Sleepwalking linked to a gene
10. Sleep Apnea Linked to Bed-Wetting in Kids
11. Race Affects Sleep in Children
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New Sleep Gene Discovery Wakes Scientists

(Date:4/27/2015)... MN (PRWEB) April 27, 2015 Based ... Secura Consultants is one of the few insurance marketing ... in the income and asset protection markets as well ... the industry has afforded Secura Consultants the opportunity to ... to make doing business easier and quicker. , An ...
(Date:4/27/2015)... Array Health , a leading provider of ... Hood, senior director of marketing, will participate in a ... Care Marketing Summit on April 29, 2015. The ... of Payer Services, Leavitt Partners, LLC, will address the ... retail/e-commerce perspective – and equip attendees with the insights ...
(Date:4/27/2015)... Thanks to a $7.5 million grant from ... institutions, including American University, will operate in a new ... behavioral research aimed at ending the AIDS epidemic. , ... HIV or AIDS, according to the latest statistics. At ... over the age of 13 was living with HIV, ...
(Date:4/27/2015)... Sitting or standing for long periods of ... and for those whose occupation requires them to be sitting ... drivers, or to be on their feet for most of ... be more severe and longer lasting. These people suffer from ... Revana of Northeast Houston Vein Center is offering tips on ...
(Date:4/27/2015)... OH (PRWEB) April 27, 2015 Douglas ... to help his clients feel secure, but also helps secure ... to 7 p.m., Douglas will be manning a booth at ... Center, Lausche Building, 717 E. 17th Ave., Columbus, Ohio. ... worthy event that will feature hundreds of adoptable pets from ...
Breaking Medicine News(10 mins):Health News:Simplified Solutions Now Makes Disability Insurance Business With Secura Consultants Even Easier! 2Health News:Array Health’s Senior Director of Marketing to Present at The Fourth Annual Direct-to-Consumer Health Care Marketing Summit 2Health News:D.C. Center for AIDS Research Established with New Grant from NIH 2Health News:D.C. Center for AIDS Research Established with New Grant from NIH 3Health News:Northeast Houston Vein Center Offers Tips on How to Treat Achy Legs 2Health News:Northeast Houston Vein Center Offers Tips on How to Treat Achy Legs 3Health News:Farmers Insurance Agent Douglas Fitzpatrick Ensures Pets Find Homes 2
... three other scientists will receive The Gairdner International Awards, ... their exemplary// research on RNAs, cell motility and hormones. ... Toronto. ,John Dirks, president of the Gairdner ... our understanding of our cells with major ramifications for ...
... Fish oil has numerous health benefits and is being touted ... its honour is welcome.Nicolas G. Bazan, MD, PhD, Boyd Professor// ... LSU Health Sciences Centre in New Orleans, in a paper ... fish oil play in protecting cells in the retina from ...
... at the University of Illinois at Chicago in collaboration ... the structure of an enzyme in the virus that ... have detailed these findings in the March 27 issue ... hope that this could form a new drug target ...
... the effect of tiny nanoparticles on the health of ... traffic exhaust and are also used in making household ... The scientists will assess if these particles damage liver ... 80,000 times smaller than the width of a human ...
... the Vagisil Women's Health CenterSM conducted a survey on feminine ... women are taking active roles in their own feminine health ... aged 18 and older (63 percent) report that they go ... gynecologist, 61 percent say they "always" go for their annual ...
... overseas doctors in Britain are alarmed as new rules ... before they can work// in hospitals of the National ... doctors from the Indian subcontinent who could suddenly ... if there are no local doctors available the first preference ...
Cached Medicine News:Health News:Women aware of “feminine health” : their attitud 2Health News:Work Permit Required For Indian Doctors in Britain 2Health News:Work Permit Required For Indian Doctors in Britain 3
(Date:4/27/2015)... 2015  Recognizing the unique position Massachusetts ... the most respected organizations in the New England medtech community, ... Industry Council (MassMEDIC), have partnered to celebrate the region,s ... Annual Massachusetts Medtech Week. This celebration will take place May ... Center in Boston . For more information ...
(Date:4/27/2015)... Mass. , April 27, 2015 ... a collaboration with Brainlab AG, a leading software-driven ... planning and surgical navigation. The collaboration provides patients ... Stimulation (DBS) therapy. DBS is intended to treat ... help reduce symptoms for movement disorders such as ...
(Date:4/27/2015)... , April 27, 2015  CryoLife, Inc. (NYSE: ... processing company focused on cardiac and vascular surgery, announced ... the United States Food and Drug Administration ("FDA") verifying ... in place following the warning letter it received from ... letter follows a re-inspection in March 2015 by the ...
Breaking Medicine Technology:First Annual Massachusetts Medtech Week Celebrated this May 2First Annual Massachusetts Medtech Week Celebrated this May 3Boston Scientific Announces Strategic Collaboration With Brainlab AG 2Boston Scientific Announces Strategic Collaboration With Brainlab AG 3Boston Scientific Announces Strategic Collaboration With Brainlab AG 4CryoLife Announces Resolution of FDA Warning Letter 2
... Corporation , today announced that the U.S. Patent and ... which brings their total portfolio to 20 and bolsters ... wireless location systems (RTLS) for hospitals. (Logo: ... cover Awarepoint,s most accurate mesh-based location algorithm to date, ...
... opening ceremony for the world,s largest stem cell medical center ... ( www.rnl.co.kr ), South Korea,s premier adult stem cell firm ... in Beijing, China. Beijing RNL Stem Cell Medical Center is ... Li Hailing, www.yandaco.com ). Beijing RNL Stem Cell Medical ...
Cached Medicine Technology:Awarepoint Advances Industry Leadership with New Patented Technology 2RNL Opens the World's Largest Stem Cell Medical Center in Beijing, China 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: