Navigation Links
New MRI Technique Measures Intracranial Pressure in Brain Disorder

A new advanced magnetic resonance imaging technique developed at the University of Illinois at Chicago for the diagnosis and treatment of neurological problems, such as// Chiari malformations, hydrocephalus and brain injury, will be evaluated for clinical use through a $1.4 million National Institutes of Health Bioengineering Research Partnership grant.

The project, which draws on bioengineering, radiology and neurosurgery, will determine the clinical potential of a non-invasive measurement of intracranial pressure to the diagnosis and treatment of patients with Chiari malformation.

The new technique relies on a novel algorithm that determines "intracranial compliance" from the change in fluid volume and pressure occurring with each heartbeat as blood and cerebral spinal fluid flow in and out of the cranium. Intracranial compliance is the ability of the intracranial compartment to accommodate an increase in volume without a large increase in pressure.

"We believe that in Chiari malformation both the severity of symptoms and the likely success of surgery are related to intracranial compliance," said Noam Alperin, UIC associate professor of medical physics and head of the MRI research laboratory. "This new method gives us a non-invasive way to study a relatively common and poorly understood neurological problem."

Chiari malformation is a condition where lower parts of the brain, the brainstem and the cerebellum, protrude downward into the spinal column. In the past, it was estimated that the condition occurs in about seven in every 1,000 births, but the increased use of diagnostic imaging has shown that it may be much more common. It can also occur later in life.

Chiari malformation can cause a wide range of symptoms, including severe headache, poor balance, dizziness, muscle weakness, numbness, and vision problems. In its most severe aspect, Chiari malformation can result in permanent neurological damage, including paralysis. Although medications can relieve pain, surgery is the only treatment currently available, and doctors have not been able to predict who will benefit, said Alperin, who is principal investigator on the project. One of the goals of the study, he said, is to improve prediction of whether surgical treatment will alleviate symptoms.

The non-invasive measurement may be useful in a range of neurological disorders, including hydrocephalus, brain injury, hemorrhages, stroke and brain tumors, Alperin said.

Swelling, which is a common response to all injury, can be fatal in brain injury, because in the restricted cranial space it increases pressure and reduces blood perfusion, Alperin said. "This technique will give us a better understanding of an individual's ability to tolerate swelling or any other space occupying processes."

Source-Newswise
'"/>




Related medicine news :

1. New Laser Techniques cure degeneration of the eye
2. New Technique to Study Infants Brain.
3. New Technique For Benign Breast Tumors
4. Preventing Strokes Using Less Invasive Techniques
5. New Technique To Detect Activity Of Drugs In The Body
6. New Technique To Test Stem Cells That Heal The Heart
7. A New Technique For Prediction Of Adult Height
8. Novel Technique For Targeting Small-Cell Lung Cancer
9. Novel Technique For Management Of Inverted Papilloma Of Frontal Sinus
10. New Cardiac Angiography Technique For Improved Imaging Of Coronary Veins
11. New Technique Enables Better Nursing Of Robin Sequence Infants
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/29/2017)... Baltimore, MD (PRWEB) , ... April 29, 2017 , ... ... noisy jobs, so what are Americans doing in their leisure time that causes hearing ... assess lifestyle habits that may be contributing to hearing loss, as well as schedule ...
(Date:4/28/2017)... (PRWEB) , ... April 28, 2017 , ... ... its new partnership with the Home Care Association of America (HCAOA). This agreement ... Private Duty Accreditation services, as well as discounts on Accreditation University (AU) educational ...
(Date:4/28/2017)... ... April 28, 2017 , ... Horizon Blue Cross Blue Shield ... credit rating of “A” and its outlook as “stable.” At the same time, the ... have fallen in recent years, dip below “capital adequacy” thresholds required for its strong ...
(Date:4/28/2017)... ... April 28, 2017 , ... ... tubes . These lamps offer an instant energy-saving solution for F32T8 fluorescent lamps ... fixtures or disconnect ballasts. These 50,000 hour rated lamps utilize the existing electronic ...
(Date:4/28/2017)... Texas (PRWEB) , ... April 28, 2017 , ... The ... plaque in recently to the labor and delivery team at Women’s Hospital at Renaissance ... mothers who give birth at the hospital and decide to donate. , “Women’s ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... 19, 2017 Global Prostate Cancer Therapeutics ... the prostate cancer therapeutics market analyzes the current ... prevalence of prostate cancer, launch of promising emerging ... of new drugs & therapeutic biological products, and ... to lesser side effects are some of the ...
(Date:4/19/2017)... The Global Effective Microorganisms (EM) Market by Manufacturers, ... and analysed the potential of Global Effective Microorganisms (EM) Market ... growth factors. The report identifies and analyses the emerging trends ... market. ... and Figures, 6 Major Company Profiles, spread across 124 pages ...
(Date:4/19/2017)... Companion animal vaccines ... pets such as canine, avian and feline. ... such as Attenuated Live Vaccines, Conjugate Vaccines, Inactivated ... Recombinant Vaccines. Attenuated live vaccines are derived from ... have been weakend under laboratory conditions. Conjugate vaccines ...
Breaking Medicine Technology: