Navigation Links
New MRI Technique Measures Intracranial Pressure in Brain Disorder

A new advanced magnetic resonance imaging technique developed at the University of Illinois at Chicago for the diagnosis and treatment of neurological problems, such as// Chiari malformations, hydrocephalus and brain injury, will be evaluated for clinical use through a $1.4 million National Institutes of Health Bioengineering Research Partnership grant.

The project, which draws on bioengineering, radiology and neurosurgery, will determine the clinical potential of a non-invasive measurement of intracranial pressure to the diagnosis and treatment of patients with Chiari malformation.

The new technique relies on a novel algorithm that determines "intracranial compliance" from the change in fluid volume and pressure occurring with each heartbeat as blood and cerebral spinal fluid flow in and out of the cranium. Intracranial compliance is the ability of the intracranial compartment to accommodate an increase in volume without a large increase in pressure.

"We believe that in Chiari malformation both the severity of symptoms and the likely success of surgery are related to intracranial compliance," said Noam Alperin, UIC associate professor of medical physics and head of the MRI research laboratory. "This new method gives us a non-invasive way to study a relatively common and poorly understood neurological problem."

Chiari malformation is a condition where lower parts of the brain, the brainstem and the cerebellum, protrude downward into the spinal column. In the past, it was estimated that the condition occurs in about seven in every 1,000 births, but the increased use of diagnostic imaging has shown that it may be much more common. It can also occur later in life.

Chiari malformation can cause a wide range of symptoms, including severe headache, poor balance, dizziness, muscle weakness, numbness, and vision problems. In its most severe aspect, Chiari malformation can result in permanent neurological damage, including paralysis. Although medications can relieve pain, surgery is the only treatment currently available, and doctors have not been able to predict who will benefit, said Alperin, who is principal investigator on the project. One of the goals of the study, he said, is to improve prediction of whether surgical treatment will alleviate symptoms.

The non-invasive measurement may be useful in a range of neurological disorders, including hydrocephalus, brain injury, hemorrhages, stroke and brain tumors, Alperin said.

Swelling, which is a common response to all injury, can be fatal in brain injury, because in the restricted cranial space it increases pressure and reduces blood perfusion, Alperin said. "This technique will give us a better understanding of an individual's ability to tolerate swelling or any other space occupying processes."

Source-Newswise
'"/>




Related medicine news :

1. New Laser Techniques cure degeneration of the eye
2. New Technique to Study Infants Brain.
3. New Technique For Benign Breast Tumors
4. Preventing Strokes Using Less Invasive Techniques
5. New Technique To Detect Activity Of Drugs In The Body
6. New Technique To Test Stem Cells That Heal The Heart
7. A New Technique For Prediction Of Adult Height
8. Novel Technique For Targeting Small-Cell Lung Cancer
9. Novel Technique For Management Of Inverted Papilloma Of Frontal Sinus
10. New Cardiac Angiography Technique For Improved Imaging Of Coronary Veins
11. New Technique Enables Better Nursing Of Robin Sequence Infants
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/8/2016)... (PRWEB) , ... December 08, 2016 , ... Coppin Insurance ... owners and families in and around the Cape Coral area, is embarking on a ... Food Bank of Southwest Florida. , The Harry Chapin Food Bank of Southwest Florida ...
(Date:12/8/2016)... ... December 08, 2016 , ... Coffey Agencies, a locally owned ... clients in the northern Alabama and Georgia regions, is embarking on a charity ... Works has built a network of support and education facilities to develop and ...
(Date:12/7/2016)... (PRWEB) , ... December 07, 2016 , ... DrugDev ... the announcement that it is one of the early adopters completing EU-U.S. Privacy Shield ... is designed to provide companies on both sides of the Atlantic with a mechanism ...
(Date:12/7/2016)... ... December 07, 2016 , ... "Today, MHA and mental ... mental health systems reform legislation in more than fifty years. We applaud the ... of our elected officials to improving mental health services and supports in our ...
(Date:12/7/2016)... ... December 07, 2016 , ... Children ... bodies, a researcher at the Icahn School of Medicine at Mount Sinai has ... found that when young children are exposed to secondhand marijuana smoke, measurable amounts ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... , Dec. 8, 2016 Henry Schein, Inc. (Nasdaq: ... care products and services to office-based dental, animal health and ... equity investment in Marrodent, one of Poland,s ... $32 million. This transaction was announced on August 30, 2016. ... Poland since 2014, and Marrodent marks ...
(Date:12/8/2016)... Dec 8, 2016 Research and Markets has announced ... report to their offering. ... , The report provides separate comprehensive ... , and Rest of World. Annual estimates and ... historic analysis is provided for these markets. Market data and analytics are ...
(Date:12/7/2016)... Dec. 7, 2016 "Lantus (Insulin Glargine) Biosimilar Clinical Trial & ... biosimilar version of Lantus drug in clinical pipeline. Currently 5 biosimilar version ... Japan , Kenya , Czech ... , China , Slovakia , ... 2 diabetes mellitus. The patent on Lantus expired in 2014. Lantus ...
Breaking Medicine Technology: