Navigation Links
New MRI Technique Measures Intracranial Pressure in Brain Disorder

A new advanced magnetic resonance imaging technique developed at the University of Illinois at Chicago for the diagnosis and treatment of neurological problems, such as// Chiari malformations, hydrocephalus and brain injury, will be evaluated for clinical use through a $1.4 million National Institutes of Health Bioengineering Research Partnership grant.

The project, which draws on bioengineering, radiology and neurosurgery, will determine the clinical potential of a non-invasive measurement of intracranial pressure to the diagnosis and treatment of patients with Chiari malformation.

The new technique relies on a novel algorithm that determines "intracranial compliance" from the change in fluid volume and pressure occurring with each heartbeat as blood and cerebral spinal fluid flow in and out of the cranium. Intracranial compliance is the ability of the intracranial compartment to accommodate an increase in volume without a large increase in pressure.

"We believe that in Chiari malformation both the severity of symptoms and the likely success of surgery are related to intracranial compliance," said Noam Alperin, UIC associate professor of medical physics and head of the MRI research laboratory. "This new method gives us a non-invasive way to study a relatively common and poorly understood neurological problem."

Chiari malformation is a condition where lower parts of the brain, the brainstem and the cerebellum, protrude downward into the spinal column. In the past, it was estimated that the condition occurs in about seven in every 1,000 births, but the increased use of diagnostic imaging has shown that it may be much more common. It can also occur later in life.

Chiari malformation can cause a wide range of symptoms, including severe headache, poor balance, dizziness, muscle weakness, numbness, and vision problems. In its most severe aspect, Chiari malformation can result in permanent neurological damage, including paralysis. Although medications can relieve pain, surgery is the only treatment currently available, and doctors have not been able to predict who will benefit, said Alperin, who is principal investigator on the project. One of the goals of the study, he said, is to improve prediction of whether surgical treatment will alleviate symptoms.

The non-invasive measurement may be useful in a range of neurological disorders, including hydrocephalus, brain injury, hemorrhages, stroke and brain tumors, Alperin said.

Swelling, which is a common response to all injury, can be fatal in brain injury, because in the restricted cranial space it increases pressure and reduces blood perfusion, Alperin said. "This technique will give us a better understanding of an individual's ability to tolerate swelling or any other space occupying processes."

Source-Newswise
'"/>




Related medicine news :

1. New Laser Techniques cure degeneration of the eye
2. New Technique to Study Infants Brain.
3. New Technique For Benign Breast Tumors
4. Preventing Strokes Using Less Invasive Techniques
5. New Technique To Detect Activity Of Drugs In The Body
6. New Technique To Test Stem Cells That Heal The Heart
7. A New Technique For Prediction Of Adult Height
8. Novel Technique For Targeting Small-Cell Lung Cancer
9. Novel Technique For Management Of Inverted Papilloma Of Frontal Sinus
10. New Cardiac Angiography Technique For Improved Imaging Of Coronary Veins
11. New Technique Enables Better Nursing Of Robin Sequence Infants
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... ... June 27, 2016 , ... ... authorized OSHA Training Institute Education Center headquartered in Northern California, has issued an ... extreme heat at their worksites. Employers with workers exposed to high temperatures ...
(Date:6/27/2016)... ... 27, 2016 , ... "FCPX editors can now reveal their media with growing ... said Christina Austin - CEO of Pixel Film Studios. , ProSlice Color brings ... users can now reveal the media of their split screens with growing colorful panels. ...
(Date:6/27/2016)... ... June 27, 2016 , ... TherapySites, the leading ... with Tennessee Counseling Association. This new relationship allows TherapySites to continue ... Association, adding exclusive benefits and promotional offers. , "TCA is extremely excited about ...
(Date:6/27/2016)... ... June 27, 2016 , ... ePAY ... partnership with Connance, a healthcare industry leader providing predictive analytics to optimize ... combine to provide health systems, hospitals and ambulatory surgical centers with dramatic ...
(Date:6/27/2016)... (PRWEB) , ... June 27, 2016 , ... ... cutting edge technology to revolutionize the emergency ambulance transport experience for the millions ... aware of how Uber has disrupted the taxi industry through the use of ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 23, 2016 Any dentist who has made an ... current process. Many of them do not even offer this ... and high laboratory costs involved. And those who ARE able ... such a high cost that the majority of today,s patients ... Parsa Zadeh , founder of Dental Evolutions Inc. and ...
(Date:6/23/2016)... 2016 Capricor Therapeutics, Inc. ... biotechnology company focused on the discovery, development and ... enrollment in its ongoing randomized HOPE-Duchenne clinical trial ... of its 24-patient target. Capricor expects the trial ... of 2016, and to report top line data ...
(Date:6/23/2016)... , June 23, 2016  Astellas today announced the establishment of Astellas Farma Colombia (AFC), a new affiliate ... in Latin America . ... ... ... ...
Breaking Medicine Technology: