A new advanced magnetic resonance imaging technique developed at the University of Illinois at Chicago for the diagnosis and treatment of neurological problems, such as// Chiari malformations, hydrocephalus and brain injury, will be evaluated for clinical use through a $1.4 million National Institutes of Health Bioengineering Research Partnership grant.
The project, which draws on bioengineering, radiology and neurosurgery, will determine the clinical potential of a non-invasive measurement of intracranial pressure to the diagnosis and treatment of patients with Chiari malformation.
The new technique relies on a novel algorithm that determines "intracranial compliance" from the change in fluid volume and pressure occurring with each heartbeat as blood and cerebral spinal fluid flow in and out of the cranium. Intracranial compliance is the ability of the intracranial compartment to accommodate an increase in volume without a large increase in pressure.
"We believe that in Chiari malformation both the severity of symptoms and the likely success of surgery are related to intracranial compliance," said Noam Alperin, UIC associate professor of medical physics and head of the MRI research laboratory. "This new method gives us a non-invasive way to study a relatively common and poorly understood neurological problem."
Chiari malformation is a condition where lower parts of the brain, the brainstem and the cerebellum, protrude downward into the spinal column. In the past, it was estimated that the condition occurs in about seven in every 1,000 births, but the increased use of diagnostic imaging has shown that it may be much more common. It can also occur later in life.
Chiari malformation can cause a wide range of symptoms, including severe headache, poor balance, dizziness, muscle weakness, numbness, and vision problems. In its most severe aspect, Chiari malformation can result in permanent neurological damage, Page: 1 2 Related medicine news :1
. New Laser Techniques cure degeneration of the eye2
. New Technique to Study Infants Brain.3
. New Technique For Benign Breast Tumors4
. Preventing Strokes Using Less Invasive Techniques5
. New Technique To Detect Activity Of Drugs In The Body6
. New Technique To Test Stem Cells That Heal The Heart7
. A New Technique For Prediction Of Adult Height 8
. Novel Technique For Targeting Small-Cell Lung Cancer9
. Novel Technique For Management Of Inverted Papilloma Of Frontal Sinus10
. New Cardiac Angiography Technique For Improved Imaging Of Coronary Veins11
. New Technique Enables Better Nursing Of Robin Sequence Infants