Navigation Links
New Hope for Regenerative Medicine

In the issue of G&D, Dr. K. John McLaughlin and colleagues report on their success in using uniparental embryonic stem cells to replace blood stem cells in mice. //Uniparental embryonic stem cells are an appealing alternative source of patient-derived embryonic stem cells, as they have several advantages over embryonic stem cell lines generated by somatic cell nuclear transfer (also known as therapeutic cloning).

Normal mammalian embryos inherit one set of chromosomes from the mother, and one set from the father. Embryos that inherit both sets of chromosomes from the same parent are not viable. They can, however, generate "uniparental" embryonic stem cell lines. Uniparental embryos with two maternal sets of chromosomes are known as parthenogenetic. These embryos have been considered a potential source of embryonic stem cell derived tissues for transplantation into the female from which they were derived.

This study shows for the first time that parthenogenetic blood cells can replace those of an immunocompromised adult mouse. McLaughlin and colleagues also show that this is also possible using embryonic stem cells where both genomes are solely derived from sperm of one male (androgenetic), adding fertile males to the potential patient pool.

Since uniparental ES cells are not derived from viable embryos, their harvesting and use sidesteps many of the ethical concerns that plague traditional ES cell therapies. However, uniparental ES cell research faces the biological hurdle of genomic imprinting, in which specific gene expression patterns are dictated by the parental origin. Uniparental cells only have the imprinting marks for one parental type (or "from one parent") with unknown consequences if harvested and transplanted into adults.

Previous work has shown that uniparental ES cells have only limited ability to contribute to fetal and postnatal development in chimeric animals, with androgenetically-derived uniparenta
'"/>




Page: 1 2 3

Related medicine news :

1. Scientists Make Major Breakthrough in Regenerative Medicine
2. Nobel Prize for Medicine shared by Three scientists
3. Prince Charles lends support to Alternative Medicine
4. Healthy Medicine Or Harmful Intoxicant?
5. Medicines on the move
6. A surge in Lifestyle Medicine
7. Does Your Prescription Have An Inappropriate Medicine?
8. The Use Of Alternative Medicine On The Rise
9. New Medicine For Parkinson’s disease
10. Advent of New, More Effective and Personalized Medicines
11. Combing Hair More Effective Than OTC Medicine For Head Lice
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New Hope for Regenerative Medicine

(Date:4/17/2014)... WINSTON-SALEM, N.C. April 17, 2014 Meaningful ... from advanced cancer of the abdomen when treated ... HIPEC, according to a first-of-its-size analysis by physicians ... Forest Baptist has the largest reported, single-center experience ... Edward A. Levine, M.D., and analysis of 20 ...
(Date:4/17/2014)... that India,s shocking rates of suicide are highest in ... to tiny smallholdings less than one hectare ... and coffee, that are highly susceptible to global price ... case studies that point to a crisis in key ... the nation,s economy during the 90s. Researchers say that ...
(Date:4/17/2014)... Queen,s University Belfast,s Vice-Chancellor, Professor Patrick Johnston, whose work ... elected as a Fellow of the European Academy of ... is an independent advisory body of highly distinguished oncologists ... and suffering caused by cancer in Europe. , Professor ... Northern Ireland move from the bottom of the UK ...
(Date:4/16/2014)... , STANFORD, Calif. Consider the marvel of the embryo. ... shape and function as they multiply to become the cells ... tissues of the body. , Now, in a feat of ... the complex genetic coding that allows embryonic cells to proliferate ...
(Date:4/16/2014)... 2014) A team that includes scientists from the School ... at San Antonio, Johns Hopkins University and St. Mary,s University ... fungus to infect the body. , The fungal pathogen ... thrush, and is the most common fungal pathogen to infect ...
Breaking Medicine News(10 mins):Health News:20 years of data shows treatment technique improvement for advanced abdominal cancer 2Health News:New evidence of suicide epidemic among India's 'marginalized' farmers 2Health News:New evidence of suicide epidemic among India's 'marginalized' farmers 3Health News:Stanford scientists develop 'playbook' for reverse engineering tissue 2Health News:Stanford scientists develop 'playbook' for reverse engineering tissue 3
... NJResearchers at Rutgers have unlocked some of the mysteries ... the amount of vitamin A present in the maternal ... 28 issue of the Journal of Biological Chemistry. ... protein that facilitates the formation of vitamin A stores ...
... of Dental Experts to Advance ... Knowledge of CCLAD in Dentistry, LIVINGSTON, N.J., Feb. ... recognized leader in,advanced injection technologies, today reported that earlier ... Anesthetic,Delivery (CCLAD) Summit in New Orleans. The Summit welcomed ...
... Hydrogen peroxide and other oxidants cause lung cells to become ... been known that smoking causes lung cancer, but a new ... in cigarette smoke is what actually causes healthy lung cells ... California, Davis, said their findings may help lead to new ...
... LAWRENCE, Mass., Feb. 28 NxStage Medical,Inc. ... Emil Paganini, MD, formerly,Section Head of Dialysis ... has joined the company as Critical Care ... for corporate clinical,scientific and educational initiatives to ...
... Director General Jean-Jacques Dordain and European Commission Director General for ... agreement which establishes the allocation of an EC budget of ... of the GMES Space Component (GSC). , This will be ... 205 million for Segment 2 of the GSC programme. Segment ...
... LOS ANGELES, Feb. 28 /PRNewswire/-- Envision,Productions has teamed ... medical,science breakthrough technique known as The Sign Chi ... campaign, 30 minute infomercial,and strategic media placement, Dr. ... our everyday lives., Dr. Anne Borik, once ...
Cached Medicine News:Health News:Rutgers researchers unlock mysteries of vitamin A metabolism during embryonic development 2Health News:Rutgers researchers unlock mysteries of vitamin A metabolism during embryonic development 3Health News:Milestone Scientific Hosts First International Computer-Controlled Local Anesthetic Delivery (CCLAD) Summit 2Health News:Milestone Scientific Hosts First International Computer-Controlled Local Anesthetic Delivery (CCLAD) Summit 3Health News:Milestone Scientific Hosts First International Computer-Controlled Local Anesthetic Delivery (CCLAD) Summit 4Health News:Milestone Scientific Hosts First International Computer-Controlled Local Anesthetic Delivery (CCLAD) Summit 5Health News:Scientists Find Cancer Culprits in Cigarette Smoke 2Health News:Emil Paganini, MD, Joins NxStage(R) as Critical Care Medical Advisor 2Health News:Emil Paganini, MD, Joins NxStage(R) as Critical Care Medical Advisor 3Health News:Space sentinels: New 'tools' in space to improve European environment and security policies 2Health News:Space sentinels: New 'tools' in space to improve European environment and security policies 3Health News:Groundbreaking Sign Chi Do Stress Management System Introduced by Dr. Anne Borik Now Available to the Public 2
(Date:1/15/2014)... Jan. 15, 2014 /PRNewswire-iReach/ -- ChinaMarketResearchReports.com adds "China Orthopedic ... . (Photo: http://photos.prnewswire.com/prnh/20140115/MN46792 ) ... policy support, China,s orthopedic instrument ... total market size rising from 3.28 billion yuan in ...
(Date:1/15/2014)...  Novation, the leading health care supply chain expertise, analytics ... (VAR) national contracts that expand its portfolio to provide ... costs. These include manufacturer product and service agreements, as ... ongoing IT consulting support. New Novation ...
(Date:1/15/2014)... 15, 2014 BreedIT Corp (OTC: BRDT), ... distributor of highly sophisticated agro-breeding solutions for plant breeders ... the Company,s board of directors appointed chemistry and pharmaceutical ... new member of the board. From 1975 ...
Breaking Medicine Technology:Orthopedic Instrument Industry in China Markets Forecast to 2015 2Orthopedic Instrument Industry in China Markets Forecast to 2015 3New Novation Information Technology VAR Contracts Offer Significant Savings to Hospitals 2BreedIT (OTC: BRDT) Appoints Chemistry and Pharmaceutical Industry Expert Dr. Ben-Zion Weiner to Its Board of Directors 2BreedIT (OTC: BRDT) Appoints Chemistry and Pharmaceutical Industry Expert Dr. Ben-Zion Weiner to Its Board of Directors 3
... PHILADELPHIA, Oct. 26 Pleio Health Support Systems, ... GoodStart(TM) medication adherence program. Retrospective analysis of ... a chronic cardiovascular medication between May 2008 and ... highly significant impact on medication adherence, resulting in ...
... Genomma Lab Internacional, S.A.B. de C.V. (BMV: LAB) ("Genomma ... quarter ended September 30, 2009. All figures included herein ... in nominal Mexican pesos. Also, the following consolidated figures show ... Mexican GAAP. , 3Q09 Highlights (vs. 3Q08) , ...
Cached Medicine Technology:Patients who Participated in Pleio GoodStart(TM) Refilled 30% Sooner and 40% More, Averaging 2 Additional Rx Refills per Patient 2Genomma Lab Internacional Announces Third Quarter 2009 Results 2Genomma Lab Internacional Announces Third Quarter 2009 Results 3
For the qualitative detection of single and multiple drugs and drug metabolites in human urine...
For the qualitative detection of single and multiple drugs and drug metabolites in human urine...
For the qualitative detection of single and multiple drugs and drug metabolites in human urine...
For the qualitative detection of single and multiple drugs and drug metabolites in human urine...
Medicine Products: