Navigation Links
New Hope for Kidney Failure

A recently discovered molecule may have the potential to protect the kidneys from failing after injury, according to new research.//

For the study, mice were genetically engineered to express higher-than-normal levels of the natural molecule hepatic growth factor (HGF) or another natural factor called parathyroid hormone-related protein (PTHrP). Both groups of mice developed normal kidney functions, thus allowing the researchers to study how the high levels of HGF and PTHrP would affect kidney recovery after blood flow to the kidney was temporarily interrupted.

Scientists found the mice that had not been genetically modified had their kidney functions sharply reduced, and the function worsened over time following the reduction in blood supply. In contrast, the mice with higher levels of HGF experienced a much lower degree of kidney damage after injury. Two days later, their kidney functions had almost completely returned to normal. Mice with high levels of HGF were also much more likely to survive after kidney injuries than mice with normal levels.

Kidney failure commonly occurs in intensive care units following a major surgery, and currently, patients who experience it have a mortality rate of about 50 percent. The researchers say it is a major cause of death in seriously ill patients. They explain acute renal failure -- or kidney failure -- occurs because of renal tubule cell death. When the researchers examined the kidneys of the genetically modified mice, they discovered the high level of HGF actually protected the renal tubule cells. These cells play an important role in the kidney's ability to produce urine.

Researchers write, "The fact that the kidneys developed normally in high-HGF and high-PTHrP mice is an important step forward in assessing the protective effects of these factors against cell damage." They call it "remarkable" that the HGF does not seem to negatively affect kidney development, yet it has a "stri
'"/>




Page: 1 2

Related medicine news :

1. Is Diabetes the Leading Cause of Kidney Failure in India
2. Kidney Stones - Interesting New Research implicates bacteria as its cause
3. Moderate Use of Analgesics - Not Associated With Kidney Dysfunction
4. New Dietary Approach To Manage Kidney Stones
5. Kidney cancer on the rise
6. Kidney function can be affected by lead exposure
7. Kidney Failure after Non-Kidney Transplants
8. Kidney Patients Risk Heart Attacks
9. Kidney Patients Risk Heart Attacks
10. Urine Test for Kidney Cancer
11. Hope for Patients With Kidney Failure
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New Hope for Kidney Failure

(Date:8/20/2014)... examined patient and tumor characteristics for melanomas with ... growth) in an effort to increase earlier detection ... , Author: Sarah Shen, M.B.B.S., B.Med.Sci., of ... Background: The tumor characteristic known as mitotic ... with prognosis and survival in melanoma patients. However, ...
(Date:8/20/2014)... 2014 Hundreds of Mirena IUD lawsuits ... who were allegedly injured due to spontaneous migration of ... Bergen County Superior Court, Bernstein Liebhard LLP reports. According ... 2014, the Court has established procedures regarding the production ... are part of the proceeding’s initial disposition pool. (In ...
(Date:8/20/2014)... Steven Reinberg HealthDay ... The speed at which cancer cells grow may help doctors ... Using this measure, investigators have found that the deadliest ... of older men with a long history of sun exposure. ... the researchers discovered. Rapid cell growth -- called ...
(Date:8/20/2014)... Aug. 20, 2014 A common approach to treating ... did not improve survival chances for people who suddenly ... at the University of Pittsburgh School of Medicine. , ... One , suggest acute hemodialysis, an aggressive method that ... may not provide a definitive benefit to the patient. ...
(Date:8/20/2014)... Research from Columbia University Medical Center shows that nerves ... and that blocking nerve signals using surgery or Botox ... The study was conducted by the laboratory of Timothy ... PhD, in Norway and is published in today,s issue ... long observed that human and mouse cancers contain a ...
Breaking Medicine News(10 mins):Health News:Patient, tumor characteristics for high-mitotic rate melanoma 2Health News:Mirena Lawsuit News: Case Management Order Issued in New Jersey Mirena Litigation, Bernstein Liebhard LLP Reports 2Health News:Mirena Lawsuit News: Case Management Order Issued in New Jersey Mirena Litigation, Bernstein Liebhard LLP Reports 3Health News:Mirena Lawsuit News: Case Management Order Issued in New Jersey Mirena Litigation, Bernstein Liebhard LLP Reports 4Health News:High-Risk Melanomas Often on Head or Neck, Study Finds 2Health News:High-Risk Melanomas Often on Head or Neck, Study Finds 3Health News:Pitt analysis questions use of acute hemodialysis treatment 2Health News:Severing nerves may shrink stomach cancers: Botox injections slow growth of tumors in mice 2
... MANHATTAN, Kan., Sept. 4 The path to poor hand sanitation ... and North Carolina State Universities. , , As ... fall, the researchers said students, actions will speak louder than words. ... their hands," said Douglas Powell, an associate professor of food safety ...
... , LOS ANGELES, Sept. 4 With an estimated ... is a TOP PRIORITY for the County,s working families and a key issue ... what is the eve of Congress, return to DC to debate healthcare reform, ... more about the importance of healthcare reform and to take action to be ...
... , , BATESVILLE, Ind., Sept. 4 ... fiscal 2009 fourth quarter dividend of $0.1025 per share. This dividend ... is payable on September 30, 2009 to shareholders of record as of ... HOLDINGS, INC. , Hill-Rom is a leading worldwide manufacturer and ...
... , MADISON, N.J., Sept. 4 Quest Diagnostics Incorporated ... information and services, today announced that it was again selected to be ... (DJSI World and DJSI North America). The company is in its sixth ... the North American Index (since 2005). , , According ...
... strategies , FRIDAY, Sept. 4 (HealthDay News) -- ... United Kingdom and Australia rethink their efforts to combat ... healthy diets and exercise -- aren,t working. , In ... , Australian researchers followed more than 250 overweight and ...
... WASHINGTON, Sept. 4 Nurses appear to be taking far better care ... survey released today by the Center for American Nurses and the Women,s ... Nurse Investor Education Survey reveals that nurses may be saving for retirement, ... most nurses say they do not know what those needs will be. ...
Cached Medicine News:Health News:Getting College Students To Wash Hands, Halt Disease, Requires Giving Them Proper Tools and Spreading The Word In Ways That Get Attention, Say K-State Expert and Colleague 2Health News:Labor Day Event to Offer Angelenos Unique Opportunity to Learn About Healthcare Reform and Send a Strong Message to Washington D.C.! 2Health News:Quest Diagnostics Marks Sixth Year on Dow Jones Sustainability Index 2Health News:Nurses and Retirement Security: A Looming Crisis? 2Health News:Nurses and Retirement Security: A Looming Crisis? 3
(Date:8/20/2014)... -- Children aren,t the only segment of our ... disease. The Centers for Disease Control and Prevention ... many adults are not following this advice. ... and the American Lung Association in partnership with ... disease, to talk with their health care provider ...
(Date:8/20/2014)... Research and Markets has ... Wound Care and Closure Market (Types, Applications, End ... Company Profiles, Demand, Insights, Analysis, Research, Report, Opportunities, ... to their offering. The new ... market (types, applications, end user and geography) - ...
(Date:8/20/2014)... LYNDHURST, N.J. , Aug. 20, 2014  Amerigen ... Amerigen Pharmaceuticals Co. Ltd., has received Chinese FDA ... Mecobalamin 0.5 mg Tablets into the ... of a marketing and distribution agreement with Sinochem ... product at its US FDA approved and China ...
Breaking Medicine Technology:American Lung Association Urges Adults with Lung Disease to Consult their Health Care Provider to Stay Current on Vaccinations 2American Lung Association Urges Adults with Lung Disease to Consult their Health Care Provider to Stay Current on Vaccinations 3Global Advanced Wound Care and Closure Market (Types, Applications, End User and Geography) - Forecast to 2020 2Amerigen Pharmaceuticals Ltd. announces that its Chinese subsidiary, Suzhou Amerigen Pharmaceuticals Co. Ltd., has received Chinese FDA (CFDA) approval and has subsequently launched its generic Mecobalamin 0.5 mg Tablets into the China domestic mark 2
The Surgiflex WAVE XP couples the state-of-the-art Surgiflex WAVE Probe with the convenience of a truly portable battery-powered pump....
Stryker Endoscopy has combined a standardized pressurizing system with an advanced hand piece design that is lightweight and compact in order to streamline laparoscopic procedures....
The original battery-operated suction and irrigation system features a new ergonomic hand piece and superior performance characteristics that have increased the overall flow rate....
... to disintegrate renal and ureteral ... technology in a compact design ... and affordable lithotripsy system. The ... of clinical results for both ...
Medicine Products: