Navigation Links
New Hope For People With Liver And Kidney Ailments

Every year there are many deaths reported owing to higher levels of ammonia in the blood resulting in liver and kidney disease. Researchers from the United States// and Japan have come out with a possible solution for this. According to an article in the April 2007 issue of The FASEB Journal, there is a similarity between the protein which secretes ammonia in pufferfish gills and human Rh blood protein. A treatment can be arrived at by targeting human Rh proteins which will people with damaged livers and kidneys in removing toxic ammonia from their bloodstream.

"Rh proteins are important targets for treatment of high toxic blood ammonia levels that occur in liver disease," said Shigehisa Hirose, co-author of the study. "Our findings also indicate that the ammonia transport system involving Rh glycoproteins is evolutionally conserved in a broad range of organisms, suggesting an essential role for surviving."

For people with kidney and liver damage, the need to remove naturally occurring ammonia from the bloodstream is critical. Brain cells are particularly susceptible to ammonia, and at low levels, ammonia toxicity can cause mild to severe confusion, drowsiness, or tremors. At high levels, ammonia toxicity leads to coma and eventually death. Rh blood proteins are most commonly recognized as being used to help define blood type. For instance, people who are type A, B, AB, or O positive have Rh blood proteins on the surface of their red blood cells. People who are type A, B, AB, or O negative do not have Rh proteins on the surface of their red blood cells.

"This study has broad implications for practically any disease or trauma affecting the liver or kidneys," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. "And the evolutionary implications make it even more compelling—hook, line, and sinker."

In addition to describing a new target for removing ammonia from the body, this study describes how fish gills are a ble to excrete ammonia at the molecular level using Rh proteins. This finding, when combined with the presence of Rh proteins in numerous organisms, adds a piece to the evolutionary puzzle, by suggesting that Rh proteins were developed very early in the evolution of animal systems, and continue to play an important role in removing toxic ammonia.

Source-Eurekalert
JYT
'"/>




Related medicine news :

1. Bad News for Short People
2. New hope on the Horizon for People Wishing to Quit Smoking
3. Prescription Drug - Helps People Stop Smoking
4. More People Seeking Treatment for Depression
5. Pain Common in People with MS
6. People with skin cancer at higher risk for other types
7. Laser Therapy Found To Help People Quit Smoking
8. Pomegranate Juice May Be The Next Best Thing For People With Heart Disease
9. New Treatment For People Allergic To Cats
10. People who fight wars may be at high risk of cardiovascular disease
11. People suffering from Alzheimer’s: can they take decisions about their treatment
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/8/2016)... Peachtree City, Ga (PRWEB) , ... December 08, ... ... and moving as soon after surgery as possible. With this in mind, SIGVARIS ... vein thrombosis (DVT or blood clot) during bed rest and provide the benefits ...
(Date:12/8/2016)... Cincinnati, OH (PRWEB) , ... December 08, 2016 ... ... offering insurance and financial planning services from offices headquartered in Hamilton County, is ... animal rescue LuvFurMutts. , LuvFurMutts specializes in finding new homes for orphaned or ...
(Date:12/8/2016)... ... December 08, 2016 , ... The Compretta Insurance Agency, a ... clients in and around the Hancock County area, is announcing the launch of a ... Pantry. , The Hancock County Food Pantry has worked for more than 30 years ...
(Date:12/7/2016)... ... December 07, 2016 , ... Students attending ... the unique opportunity to get hands-on experience in an emergency medical simulation, When ... experience to gain invaluable, real-life medical skills that are critical success in a ...
(Date:12/7/2016)... ... December 07, 2016 , ... ... wrinkles and deep lines by smoothing and tightening the skin of the face ... there to address facial aging with very little downtime, Silhouette Instalift is a ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... LITTLE FALLS, N.J., Dec. 8, 2016 CANTEL MEDICAL ... net income of $18,800,000, or $0.45 per diluted share, on ... the first quarter ended October 31, 2016. This compares with ... sales of $153,779,000 for the first quarter ended October 31, ... the first quarter ended October 31, 2016 to $21,323,000, or ...
(Date:12/8/2016)... 8, 2016 Research and Markets has announced the ... report to their offering. ... The report provides separate comprehensive analytics ... , and Rest of World. Annual estimates and forecasts ... analysis is provided for these markets. Market data and analytics are derived ...
(Date:12/7/2016)... 7, 2016 KEY FINDINGS ... such as reducing loss of blood during surgeries, ... arrests, rapid recovery after surgeries, and decreasing risks ... segmented into convective warming system, surface warming systems, ... reduce the stay at hospitals thus, lowering the ...
Breaking Medicine Technology: