Navigation Links
New Hair in 15 Days Could Now Be A Possibility Say Researchers

Adult hair follicles undergo a growth cycle consisting of periods of growth (anagen), regression (catagen), and rest (telogen). Researchers demonstrated that the brief activation of ?-catenin in // telogen-phase adult hair follicles is sufficient to initiate the anagen phase. Scientists have discovered that the transient activation of a protein called ?-catenin can induce new hair growth.

Previous work has implicated Wnt/?-catenin signaling in embryonic hair follicle development, postnatal follicle growth and maturation, and skin tumor formation. This new work provides important insight into the role of ?-catenin as a trigger for activating the normal growth of adult hair follicles.

Researchers generated transgenic mice expressing an inactive version of ?-catenin in their skin and hair follicles. Upon topical treatment of the mice with a chemical called 4-OHT, the exogenous ?-catenin protein is activated. Thus, through the cutaneous application of 4-OHT, the researchers could transiently activate ?-catenin signaling at will.

To test the effect of ?-catenin signaling on adult hair growth, the researchers shaved the backs of telogen-phase transgenic and wild-type mice, and then applied 4-OHT once. Within 15 days, the transgenic mice grew new hair, whereas wild-type still had none . Furthermore, the new hair was histologically indistinguishable from normal hair, and progressed through the remainder of the growth cycle in stereotypical fashion.

It was found that brief activation of ?-catenin in resting hair follicles is sufficient to trigger a normal follicle growth phase, followed by the expected regression and resting phases. ?-catenin acts specifically on epithelial hair follicle progenitor cells, triggering a highly coordinated program of proliferation followed by expansion into the multiple differentiated cell types that comprise the mature, growing hair follicle. In contrast to the effects of transient and regulated beta-cat enin activation, prolonged activation of ?-catenin leads to uncontrolled growth and gross distortion of the hair follicle structure, underscoring the importance of precisely controlled signaling activity for normal follicle regeneration.
'"/>




Related medicine news :

1. Lean Protein Could Be Key to Obesity Drugs
2. Nasal Spray Could Take Drugs Direct to Brain.
3. Nasal Spray Could Take Drugs Directly to Brain
4. Oxygen Usage During Exercise Could Indicate Heart Problems
5. Ultrasound Screening Could Improve The Outcome Of Critically ill Patients
6. Anger Could Be Linked To Weight Gain
7. A Seizure Late In Life Could be A Stroke Warning
8. New Findings Could Reduce The Extent Of Spinal Cord Injuries
9. Could There Be A Link Between Famine and Breast Cancer ?
10. Bone Marrow Cells Could Yield A New Lease of Life
11. Your Wheezing Could be Due To Your Bed
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/2/2016)... ... May 02, 2016 , ... Pets bring laughter, joy and love ... pet owners celebrate National Pet Week, which falls on the first full week of ... to cherish the human-animal bond and recognize responsible pet ownership. Pet owners can live ...
(Date:5/2/2016)... ... May 02, 2016 , ... “Engineering Bubbles,” an oil painting submitted by Canadian ... Forum held recently at the Annual Meeting in Los Angeles. The first annual art ... members and Annual Meeting attendees. , “Through art I hope to educate people ...
(Date:5/2/2016)... ... May 02, 2016 , ... Over $60 Billion is spent ... pet gear and toys, leading product review site for Toys, Tots, Pets & More ... at their Spring Showcase at the Metropolitan Pavilion in New York City. , ...
(Date:5/2/2016)... NV (PRWEB) , ... May 02, 2016 , ... ... Pharmacy Times, has announced a new Specialty Pharmacy Patient Satisfaction Award that will ... based on the quarterly results from Zitter Health Insights’ Specialty Pharmacy Patient Satisfaction ...
(Date:5/2/2016)... ... May 02, 2016 , ... According to an American Psychological ... girls are sexually abused before the age of 18. Of those who survive, many ... story and others. , In her new book, Lyah! Lyah! Pants on Fyah!, ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... -- Treato , the single largest ... that it has been named a Cool Vendor by ... Sciences, 2016, Stephen Davies , Michael ... life-science- oriented analytics, algorithms and smart machine technology in ... medication ingestion, and analyze unstructured information.   ...
(Date:4/28/2016)... Oramed Pharmaceuticals Inc. (NASDAQ: ORMP ) ( ... of oral drug delivery systems, announced today that the Company ... Joseph Gunnar & Co. LLC, taking place on ... Nadav Kidron , CEO of Oramed, will present a ...   PIONEERS 2016, presented by Joseph Gunnar ...
(Date:4/28/2016)... TapImmune,Inc. (TPIV), a clinical-stage immune-oncology company ... and vaccines for the treatment of cancer & metastatic disease, ... Growth Capital Expo to be held on May 3 ... in Las Vegas, Nevada.  The Company presentation will be ... by Dr. John N. Bonfiglio a TapImmune Board ...
Breaking Medicine Technology: