Navigation Links
New Hair in 15 Days Could Now Be A Possibility Say Researchers

Adult hair follicles undergo a growth cycle consisting of periods of growth (anagen), regression (catagen), and rest (telogen). Researchers demonstrated that the brief activation of ?-catenin in // telogen-phase adult hair follicles is sufficient to initiate the anagen phase. Scientists have discovered that the transient activation of a protein called ?-catenin can induce new hair growth.

Previous work has implicated Wnt/?-catenin signaling in embryonic hair follicle development, postnatal follicle growth and maturation, and skin tumor formation. This new work provides important insight into the role of ?-catenin as a trigger for activating the normal growth of adult hair follicles.

Researchers generated transgenic mice expressing an inactive version of ?-catenin in their skin and hair follicles. Upon topical treatment of the mice with a chemical called 4-OHT, the exogenous ?-catenin protein is activated. Thus, through the cutaneous application of 4-OHT, the researchers could transiently activate ?-catenin signaling at will.

To test the effect of ?-catenin signaling on adult hair growth, the researchers shaved the backs of telogen-phase transgenic and wild-type mice, and then applied 4-OHT once. Within 15 days, the transgenic mice grew new hair, whereas wild-type still had none . Furthermore, the new hair was histologically indistinguishable from normal hair, and progressed through the remainder of the growth cycle in stereotypical fashion.

It was found that brief activation of ?-catenin in resting hair follicles is sufficient to trigger a normal follicle growth phase, followed by the expected regression and resting phases. ?-catenin acts specifically on epithelial hair follicle progenitor cells, triggering a highly coordinated program of proliferation followed by expansion into the multiple differentiated cell types that comprise the mature, growing hair follicle. In contrast to the effects of transient and regulated beta-cat enin activation, prolonged activation of ?-catenin leads to uncontrolled growth and gross distortion of the hair follicle structure, underscoring the importance of precisely controlled signaling activity for normal follicle regeneration.
'"/>




Related medicine news :

1. Lean Protein Could Be Key to Obesity Drugs
2. Nasal Spray Could Take Drugs Direct to Brain.
3. Nasal Spray Could Take Drugs Directly to Brain
4. Oxygen Usage During Exercise Could Indicate Heart Problems
5. Ultrasound Screening Could Improve The Outcome Of Critically ill Patients
6. Anger Could Be Linked To Weight Gain
7. A Seizure Late In Life Could be A Stroke Warning
8. New Findings Could Reduce The Extent Of Spinal Cord Injuries
9. Could There Be A Link Between Famine and Breast Cancer ?
10. Bone Marrow Cells Could Yield A New Lease of Life
11. Your Wheezing Could be Due To Your Bed
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/21/2019)... ... August 21, 2019 , ... ... to know? , A video accompanying this announcement is available at: https://youtu.be/D-65LmBhJhU ... storm. CBD products can be found on the internet, wellness catalogs, small ...
(Date:8/21/2019)... ... 2019 , ... Never Bean Better, Inc. announces that “Bean”, ... popular, registered therapy dog, television actor, and canine spokes dog, landed a national ... National Day Calendar has declared Never Bean Better Day to be observed August ...
(Date:8/21/2019)... ... August 21, 2019 , ... ... on Sunday, July 28. The Phase II expansion of Providence Point in Pittsburgh’s ... as well as construction of the 70-unit apartment tower, Hamilton Tower. ...
(Date:8/19/2019)... ... August 19, 2019 , ... ProRehab Louisville and Dr. Stacie Grossfeld have ... and to access to top-notch sports medical care and sport injury experts for rehabilitation. ... demands of ice skating, knows the individualized treatment plan, and understands what a triple ...
(Date:8/19/2019)... (PRWEB) , ... August 18, 2019 , ... ... Recovery, today launches its third product, Aqua+, adding two SKUs to its line ... users faster and more effectively than water alone. Distinguishing Aqua+ from other rehydration ...
Breaking Medicine News(10 mins):
(Date:8/21/2019)... Md. (PRWEB) , ... August 21, 2019 , ... As ... first experiences with being evaluated or treated for speech and language disorders through the ... are worried about their child’s communication: Recent national polling commissioned by the ...
(Date:8/21/2019)... (PRWEB) , ... August 21, 2019 , ... The latest ... and is now available on the company’s global website. , Crystallography Times is a ... and serves the X-ray analysis community by presenting the latest news and crystallographic research. ...
(Date:8/21/2019)... BOSTON (PRWEB) , ... August ... ... today announced the latest release of its Wellness Check Module for its ... rehabilitation centers perform more effective wellness checks on their discharged patients. ...
Breaking Medicine Technology: