Navigation Links
New Hair in 15 Days Could Now Be A Possibility Say Researchers

Adult hair follicles undergo a growth cycle consisting of periods of growth (anagen), regression (catagen), and rest (telogen). Researchers demonstrated that the brief activation of ?-catenin in // telogen-phase adult hair follicles is sufficient to initiate the anagen phase. Scientists have discovered that the transient activation of a protein called ?-catenin can induce new hair growth.

Previous work has implicated Wnt/?-catenin signaling in embryonic hair follicle development, postnatal follicle growth and maturation, and skin tumor formation. This new work provides important insight into the role of ?-catenin as a trigger for activating the normal growth of adult hair follicles.

Researchers generated transgenic mice expressing an inactive version of ?-catenin in their skin and hair follicles. Upon topical treatment of the mice with a chemical called 4-OHT, the exogenous ?-catenin protein is activated. Thus, through the cutaneous application of 4-OHT, the researchers could transiently activate ?-catenin signaling at will.

To test the effect of ?-catenin signaling on adult hair growth, the researchers shaved the backs of telogen-phase transgenic and wild-type mice, and then applied 4-OHT once. Within 15 days, the transgenic mice grew new hair, whereas wild-type still had none . Furthermore, the new hair was histologically indistinguishable from normal hair, and progressed through the remainder of the growth cycle in stereotypical fashion.

It was found that brief activation of ?-catenin in resting hair follicles is sufficient to trigger a normal follicle growth phase, followed by the expected regression and resting phases. ?-catenin acts specifically on epithelial hair follicle progenitor cells, triggering a highly coordinated program of proliferation followed by expansion into the multiple differentiated cell types that comprise the mature, growing hair follicle. In contrast to the effects of transient and regulated beta-cat enin activation, prolonged activation of ?-catenin leads to uncontrolled growth and gross distortion of the hair follicle structure, underscoring the importance of precisely controlled signaling activity for normal follicle regeneration.
'"/>




Related medicine news :

1. Lean Protein Could Be Key to Obesity Drugs
2. Nasal Spray Could Take Drugs Direct to Brain.
3. Nasal Spray Could Take Drugs Directly to Brain
4. Oxygen Usage During Exercise Could Indicate Heart Problems
5. Ultrasound Screening Could Improve The Outcome Of Critically ill Patients
6. Anger Could Be Linked To Weight Gain
7. A Seizure Late In Life Could be A Stroke Warning
8. New Findings Could Reduce The Extent Of Spinal Cord Injuries
9. Could There Be A Link Between Famine and Breast Cancer ?
10. Bone Marrow Cells Could Yield A New Lease of Life
11. Your Wheezing Could be Due To Your Bed
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... ... June 25, 2016 , ... The temporary closing of Bruton Memorial Library on June 21 due ... up a new, often overlooked aspect of head lice: the parasite’s ability to live away ... a common occurrence, but a necessary one in the event that lice have simply gotten ...
(Date:6/25/2016)... ... June 25, 2016 , ... Dr. Calvin Johnson ... Recently, he has implemented orthobiologic procedures as a method for treating his patients. ... the first doctors to perform the treatment. Orthobiologics are substances that orthopaedic surgeons ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic events may ... to unhealthy avenues, such as drug or alcohol abuse, as a coping mechanism. To ... for healthy coping following a traumatic event. , Trauma sufferers tend to feel a ...
(Date:6/24/2016)... ... ... Global law firm Greenberg Traurig, P.A. announced that 20 Florida attorneys are ... for this recognition are considered among the top 2 percent of lawyers practicing within ... of this year’s Legal Elite Hall of Fame: Miami Shareholders Mark D. Bloom, ...
(Date:6/24/2016)... ... 2016 , ... People across the U.S. are sharpening their pencils and honing ... contest in which patients and their families pay tribute to a genetic counselor by ... Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. , In ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... -- Revolutionary technology includes multi-speaker listening to ... leaders in advanced audiology and hearing aid technology, has ... the world,s first internet connected hearing aid that opens ...      (Photo: http://photos.prnewswire.com/prnh/20160622/382240 ) , ... firsts,: , TwinLink™ - the first dual ...
(Date:6/23/2016)... , June 23, 2016 The vast majority ... outpatient dialysis facility.  Treatments are usually 3 times a ... per visit, including travel time, equipment preparation and wait ... but especially grueling for patients who are elderly and ... skilled nursing and rehabilitation centers for some duration of ...
(Date:6/23/2016)... FRANKLIN, Tenn. , June 23, 2016 ... for automating, integrating and transforming the patient ... launch of several innovative new products and ... depth of its revenue cycle offerings. These ... establish more efficient workflows, remain compliant in ...
Breaking Medicine Technology: