Navigation Links
New Group Of Drugs For HIV Treatment

In a breakthrough move against HIV drug resistance, scientists have now developed a group of drugs called Maturation Inhibitors that is the first in a new class of HIV drug candidates //.

Designed to prevent the formation of Caspsid, a key viral protein from its precursor protein,this group of drug in question, PA- 457, is a derivative of betulinic acid, and interferes with the production of the capsid conical shield which surrounds the genetic material of the HIV inside it.

Approximately 80 per cent of people on treatment for HIV show resistance to one or more of the prevalent drugs and this figure is likely to rise as the treatment options become incapable of coping with the increase in the rate of infection.

The article, published in the Journal of Virology, concluded that the drug PA-457 prevents the release of Capsid only when Gag is in an assembled form, which has a specific three-dimensional conformation , and not in the unassembled form. The study also observed that no other viral proteins or human cellular component are a requirement for PA-457 activity.

Despite the success, the researchers have reiterated the importance of further testingespecially how the drugs work in combination with other drugs..They predicted that it would be at least 2009 before the drug is made available to the common man. It must be noted here,that antiretroviral drugs prevent the HIV from copying its DNAinto the human genome,while the protease inhibitorspreventthe production of new viral particles.

A recent market report put forth by Datamonitor suggests that by 2012, global sales could be just under $12 billion (€9.2 billion), which approximately double the value recorded for 2003 ($5.76 billion).


Page: 1

Related medicine news :

1. Suicide risk high in 12-17 Age Group
2. Wockhardt Group Plans Hospital In Delhi By End-2007
3. Group Suicides On The Rise In Japan
4. Yogic Moments: Age Old Yoga, Benefits All Age Groups
5. Group Jogging More Beneficial To Health Than Solo Jogging
6. Plastic Surgery Is Primetime among Ethnic Groups
7. Study Finds Online Support Groups Emotionally Benefit Women Suffering From
8. Specialist Services Can Help Ethnic Groups To Tackle Alcohol Misuse
9. Distinct Support Services Needed, To Resurrect Ethnic Groups from Alcohol Abuse
10. Low Awareness Of Kawasaki Disease In Capital: Parents Form Support Group
11. NGOs and Various Groups Come Together To Address the Issues on AIDS
Post Your Comments:

(Date:6/25/2016)... ... 2016 , ... On Friday, June 10, Van Mitchell, Secretary of the Maryland ... iHire in recognition of their exemplary accomplishments in worksite health promotion. , The Wellness ... & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was one of ...
(Date:6/24/2016)... , ... June 24, 2016 , ... June 19, 2016 ... dangers associated with chronic pain and the benefits of holistic treatments, Serenity Recovery ... are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a disorder ...
(Date:6/24/2016)... ... 24, 2016 , ... Dr. Amanda Cheng, an orthodontist ... has extensive experience with all areas of orthodontics, including robotic Suresmile technology, ... , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It can be used ...
(Date:6/24/2016)... ... June 24, 2016 , ... EB Medicine presented its first-ever ... Medicine conference in Ponte Vedra Beach, FL. The awards honor the outstanding work ... Practice and Pediatric Emergency Medicine Practice. , “With this award, we recognize ...
(Date:6/24/2016)... ... June 24, 2016 , ... National recruitment firm Slone Partners ... with extensive sequencing and genomics experience, as Vice President of North American Capital Sales ... be responsible for leading the sales team in the commercialization of the HTG EdgeSeq ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Research ... Devices Global Market - Forecast to 2022" report to ... the treatment method for the patients with kidney failure, it ... excess fluid from the patient,s blood and thus the treatment ... potassium and chloride in balance. Increasing number ...
(Date:6/23/2016)... , June 23, 2016 Roche (SIX: RO, ... clearance for its Elecsys BRAHMS PCT (procalcitonin) assay as ... or septic shock. With this clearance, Roche is the ... fully integrated solution for sepsis risk assessment and management. ... bacterial infection and PCT levels in blood can aid ...
(Date:6/23/2016)... WAYNE, Pa. , June 23, 2016 ... provider, will launch its next generation clinical outcomes platform, Bracket ... DIA Meeting held on June 26 – 30, 2016 in ... 6.0, the first electronic Clinical Outcome Assessment product of its ... DIA Booth #715. Bracket eCOA 6.0 is a ...
Breaking Medicine Technology: