Navigation Links
New Group Of Drugs For HIV Treatment

In a breakthrough move against HIV drug resistance, scientists have now developed a group of drugs called Maturation Inhibitors that is the first in a new class of HIV drug candidates //.

Designed to prevent the formation of Caspsid, a key viral protein from its precursor protein,this group of drug in question, PA- 457, is a derivative of betulinic acid, and interferes with the production of the capsid conical shield which surrounds the genetic material of the HIV inside it.

Approximately 80 per cent of people on treatment for HIV show resistance to one or more of the prevalent drugs and this figure is likely to rise as the treatment options become incapable of coping with the increase in the rate of infection.

The article, published in the Journal of Virology, concluded that the drug PA-457 prevents the release of Capsid only when Gag is in an assembled form, which has a specific three-dimensional conformation , and not in the unassembled form. The study also observed that no other viral proteins or human cellular component are a requirement for PA-457 activity.

Despite the success, the researchers have reiterated the importance of further testingespecially how the drugs work in combination with other drugs..They predicted that it would be at least 2009 before the drug is made available to the common man. It must be noted here,that antiretroviral drugs prevent the HIV from copying its DNAinto the human genome,while the protease inhibitorspreventthe production of new viral particles.

A recent market report put forth by Datamonitor suggests that by 2012, global sales could be just under $12 billion (€9.2 billion), which approximately double the value recorded for 2003 ($5.76 billion).


'"/>




Page: 1

Related medicine news :

1. Suicide risk high in 12-17 Age Group
2. Wockhardt Group Plans Hospital In Delhi By End-2007
3. Group Suicides On The Rise In Japan
4. Yogic Moments: Age Old Yoga, Benefits All Age Groups
5. Group Jogging More Beneficial To Health Than Solo Jogging
6. Plastic Surgery Is Primetime among Ethnic Groups
7. Study Finds Online Support Groups Emotionally Benefit Women Suffering From
8. Specialist Services Can Help Ethnic Groups To Tackle Alcohol Misuse
9. Distinct Support Services Needed, To Resurrect Ethnic Groups from Alcohol Abuse
10. Low Awareness Of Kawasaki Disease In Capital: Parents Form Support Group
11. NGOs and Various Groups Come Together To Address the Issues on AIDS
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New Group Drugs For HIV Treatment

(Date:7/12/2014)... Demand Response Management Systems is a crucial ... the imbalance between energy supply and demand. With the ... out (due to increasing pressure on the grid) and ... controlling residential appliances and thermostats for load reduction. ... region, and with government mandates and benefits for energy ...
(Date:7/12/2014)... (PRWEB) July 12, 2014 Casinos ... years, despite rising competition from international and online casinos. ... 2.9% over the five years through 2014-15. Greater per ... demanding more gaming services. Rises in discretionary income levels ... more money on non-essential items such as casino gambling ...
(Date:7/12/2014)... 2014 Sean Francis, owner of the Kawartha Lakes ... to his clients. He’s also known for his support of local ... way to combine the two and is excited to announce that ... Boys and Girls Club. , The funds are the result of ... 23rd. Francis sent out emails and asked his clients to put ...
(Date:7/12/2014)... prom shopping reaching its final days, VogueQueen.com, a renowned ... its new and trendy apparels. Recently, the company has ... online shop. Additionally, it is now providing huge discounts ... to the company’s sales manager, the promotion will come ... He says, “Now, worldwide clients can order cheap ...
(Date:7/12/2014)... 12, 2014 Doylestown Hospital recently conducted ... of men’s health questions. Paddock tackles topics including ... why women live longer than men, and testosterone replacement ... Made Simple featured on Doylestown Hospital’s website, Dr. ... at any age. If you notice pain, bulging, or ...
Breaking Medicine News(10 mins):Health News:North America Demand Response Management System Worth $12,522.4 Million by 2019 - New Report by MicroMarket Monitor 2Health News:North America Demand Response Management System Worth $12,522.4 Million by 2019 - New Report by MicroMarket Monitor 3Health News:North America Demand Response Management System Worth $12,522.4 Million by 2019 - New Report by MicroMarket Monitor 4Health News:Casinos in Australia Industry Market Research Report Now Updated by IBISWorld 2Health News:Casinos in Australia Industry Market Research Report Now Updated by IBISWorld 3Health News:Casinos in Australia Industry Market Research Report Now Updated by IBISWorld 4Health News:Kawartha Lakes Fit Body Boot Camp’s Successful Fat Loss Challenge Results in $2,000 to Boys and Girls Club 2Health News:Kawartha Lakes Fit Body Boot Camp’s Successful Fat Loss Challenge Results in $2,000 to Boys and Girls Club 3Health News:VogueQueen.com Updates Its Summer Collection With New And Trendy Evening Dresses 2Health News:Ivyland Medical Center’s Dr. Brad Paddock Offers Tips for Men’s Health 2
... key component of butter flavoring in microwave brands , SATURDAY, ... the buttery flavoring of microwave popcorn has been identified as ... afflicts people who work in the microwave popcorn manufacturing industry, ... issue of the American Journal of Respiratory and Critical ...
... bedtime pay the price down the road, European researchers say , , ... asleep in their morning cereal, check their cell phones -- even ... needed sleep. , A new study found that teens who reported ... doubled their odds of being very tired a year later. Those ...
... and other racial minorities have sleep durations associated with ... that unhealthy sleep patterns among minorities long sleep ... according to a study published in the September 1 ... by Lauren Hale, PhD, assistant professor in the graduate ...
... Work time is the primary lifestyle factor with the ... more hours a person works, the less sleep that he ... September 1 issue of the journal SLEEP. , The study, ... focused on a total of 47,731 respondents to the American ...
... Calif., Aug. 31 DaVita Inc.,(NYSE: DVA ), ... complaint filed,in U.S. District Court for the Central District ... The complaint names as defendants,Amgen, Inc., Fresenius Medical Care ... yet been served on DaVita, is styled as a ...
... KIDS OF KILIMANJARO ANNUAL GALA, Program provides school lunches to over 10,000 students ... ... Calif., Aug. 31 When Mary and,Joseph Mwanisawa agreed to travel over 15,000 ... lunch program, they,thought they were going to America only to tell their story ...
Cached Medicine News:Health News:Scientists ID Likely Culprit in 'Popcorn Lung' 2Health News:Teens' Cell Talk at Night Can Be Tiring 2Health News:Minorities more likely to have sleep durations associated with increased mortality 2Health News:Minorities more likely to have sleep durations associated with increased mortality 3Health News:Work time is the largest influence to the duration of a person's sleep 2Health News:Father and Daughter From Tanzania Receive Their First Medical Examination in Newport Beach 2Health News:Father and Daughter From Tanzania Receive Their First Medical Examination in Newport Beach 3
(Date:7/11/2014)... MELBOURNE, Australia , July 11, 2014  Australian ... today announced that it has raised A$19.3 million via ... Europe , the U.S., ... and A$3 million from a share purchase plan (SPP) ... A$16.3 million will be made in two tranches. ...
(Date:7/11/2014)... 2014 Research and Markets ( http://www.researchandmarkets.com/research/tjlw9k/immunoprotein ... "Immunoprotein Diagnostic Testing Market - Forecasts to 2019: ... 6% and is expected to be valued at ... http://photos.prnewswire.com/prnh/20130307/600769 ... been segmented according to immunoprotein types which include ...
(Date:7/11/2014)... 2014 Neurelis, Inc. ("Neurelis") today announced an ... option held by Biotie to purchase Neurelis, clearing the ... (intranasal diazepam) for pediatric and adult epilepsy patients who ... year, Biotie has advanced the development program for NRL-1 ... clinical work required for NDA submission to the FDA.  ...
Breaking Medicine Technology:Phosphagenics' A$19.3 million Capital Raising 2Phosphagenics' A$19.3 million Capital Raising 3Immunoprotein Diagnostic Testing Market - Forecasts to 2019: Expected to grow at the highest CAGR of 6% and is expected to be valued at USD 4,943.0 million 2Neurelis Regains Rights to Intranasal Diazepam Program 2Neurelis Regains Rights to Intranasal Diazepam Program 3
...  Millennium Laboratories announced today the Clinical Laboratory Responsibility ... responsible and ethical business practices in the medication ... which Millennium adheres and to which the company ... industry to adopt. (Logo: ...
... Inc., a critical care company focused on developing and commercializing ... Center for Devices and Radiological Health ... Administration (FDA) has granted 510(k) clearance for compatibility of its ... INOMAX DS and the INOMAX DSIR have now been validated ...
Cached Medicine Technology:Millennium Laboratories Announces Laboratory Responsibility Pledge 2Millennium Laboratories Announces Laboratory Responsibility Pledge 3FDA Clears Expanded Compatibility for INOMAX® Drug-Delivery Systems 2FDA Clears Expanded Compatibility for INOMAX® Drug-Delivery Systems 3
... Hand-Held Pulse Oximeter provides SpO 2 and ... adult. The device is battery or AC ... visible and audible alarm signals, and an infrared ... rubber boot is also available for added protection. ...
... Hand-Held Pulse Oximeter with built-in Summary ... screening studies in the sleep lab, ... its easy-to-use, 2-key operation, it also ... SpO 2 , pulse rate and ...
... is a cost-effective, stand-alone monitor that delivers ... and pulse strength measurements of patients from ... battery powered unit displays a plethysmographic waveform, ... to 30 hours of on screen trended ...
... Administration (FDA) has granted approval of Alcon's ... patients with and without presbyopia. This innovative ... to give patients a full range of ... greatly increases their independence from glasses after ...
Medicine Products: