Navigation Links
New Gastric Cancer Drug Unlikely to Benefit Kidney Cancer Patients

An article appearing in the January issue of The Journal of Urology says that drugs used to treat gastrointestinal stromal cancers (GISTs) are likely to be ineffective for// patients with full blown kidney cancer.

These findings are reported by investigators at the Mayo Clinic Cancer Center, who say that the drug in question is not going to help patients with high grade renal cell carcinoma. "While this finding does not seem like good news for patients with kidney cancer," said Bradley Leibovich, M.D., Mayo Clinic urologist and lead investigator of the study, "it does help us to narrow down the treatment options among the new targeted therapy drugs and would seem to indicate that resources for investigating potential new kidney cancer therapies may be better utilized on other options."

The current study wanted to verify a previous study published in 2004 in The Journal of Clinical Pathology. They reviewed the data of all patients who had undergone partial or radical nephrectomy between 1970 and 2002. This study had found that kidney tumors often expressed KIT (a receptor kinase tyrosine) mutations. Another study appearing in The Journal of Urology had also reported on the prevalence of these type of mutations in kidney tumors. Dr. Leibovich's team wanted to verify these findings since these tumors are very aggressive and recur even after surgery. If the findings were corroborated, then new drugs could have been used in the treatment process. But the researchers found no evidence of this since only 4.5 percent of tumors exhibited KIT mutations. "Imatinib only would have had the potential to be helpful to that small percentage of patients that we found to have a KIT-positive tumor," says lead author Shomik Sengupta, M.D. "And even then it would only work if they also had specific mutations that would respond to the drug." These findings led the researchers to conclude that imatinib therapy could not be justified in all kidney cancer. "Tumors that
'"/>




Page: 1 2

Related medicine news :

1. The Reason For Loss Of Appetite After Gastric Bypass
2. Gastric bypass surgery reduces risk of heart disease
3. Surgeons Perform Robotic Gastric Bypass Surgery
4. Helicobacter pylori Antibiotic Treatment of Peptic Ulcer May not Prevent Gastric lymphomas
5. Migraine Patients Suffer From Gastric Stasis
6. Gastric Bypass And Laparoscopic Reflux Surgery Gaining Popularity
7. Gastric bypass can cause deficiency of Vitamin A
8. For Super-Obese Patients, Duodenal Switch Beats Gastric Bypass
9. Long-time Gastric Acid Suppression Does Not Increase The Risk Of Cancer
10. Gastric Bypass Surgery May Lead to Increased Kidney Stone Risk
11. Robotically Assisted Colo-resection And Gastric Bypass Surgeries Are Becoming Popular
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New Gastric Cancer Drug Unlikely Benefit Kidney Cancer Patients

(Date:5/3/2015)... May 03, 2015 Looking for ... will directly impact your career? The Master of ... dynamic leaders in multinational companies and for professionals ... a changing global landscape, differences in culture, religion, ... The EMIB program develops the global competence and ...
(Date:5/3/2015)... May 03, 2015 It is not too late ... Aneurysm Walk in Memory of Lissa Anne Been in Arnold, ... this great family-friendly event to honor her loving memory. It has ... , Just having turned 37, Lissa suffered a brain ... on August 24, 2012. This event is designed to serve as ...
(Date:5/2/2015)... NV (PRWEB) May 02, 2015 Ticket Down ... tickets for the long awaited event today, Saturday, May ... Diehard boxing fans will be able to secure tickets ... , The fight that boxing fans have wanted for more ... months ago. Floyd “Money” Mayweather will step inside the ring ...
(Date:5/2/2015)... ProText Kinetic 2 is a set of ... Pro X. ProText Kinetic 2 features 40 animation ... Pro X . Easily create interactive text videos without ... ProText Kinetic 2. , Using ProText Kinetic is as easy ... Kinetic presets in the FCPX timeline. Playback the default ...
(Date:5/2/2015)... 02, 2015 “ Peachtree Audio ” ... Tech Report, which features the latest and coolest technology ... and special reporter for NewsWatch, conducted the review and ... equipment. , Music is an important part of ... pampered and given the royal treatment. Peachtree Audio does ...
Breaking Medicine News(10 mins):Health News:The Saint Louis University's Master of International Business Is Now Enrolling For Fall 2015 2Health News:Renowned Brain Aneurysm Foundation to Benefit from Arnold, Missouri’s 3rd Annual Brain Aneurysm Walk in Memory of Lissa Anne Been 2Health News:Cheap Floyd Mayweather vs. Manny Pacquiao Tickets: Ticket Down Has Last Minute Tickets for Mayweather vs. Pacquiao at the MGM Grand Garden Arena in Las Vegas 2Health News:Cheap Floyd Mayweather vs. Manny Pacquiao Tickets: Ticket Down Has Last Minute Tickets for Mayweather vs. Pacquiao at the MGM Grand Garden Arena in Las Vegas 3Health News:Pixel Film Studios Announced the Release of Protext Kinetic 2 for FPCX. 2Health News:Affordable High-End Audio Equipment was Featured on NewsWatch Television 2
... Mary, University of London suggests that many cases of diabetes ... The study, published today in the British Medical ... for predicting with reasonable accuracy who will develop diabetes but ... that if these tools were used by GPs and members ...
... , MONDAY, Nov. 28 (HealthDay News) -- About one in ... will land back in the hospital within 30 days, a ... that rehospitalization after angioplasty or stent placement remains a risk ... appear in the Nov. 28 issue of the Archives ...
... same filtered light that enables sunglasses to reduce glare ... of cervical cancer, reducing unnecessary biopsies and surgery. , ... which scatters in all directions, said Dr. Daron G. ... Gynecologic Cancer Prevention Center at Georgia Health Sciences University. ...
... history of breast cancer are just as likely to develop ... of the disease, according to a study presented today at ... (RSNA). These findings indicate that women in this age group ... cancer screening guidelines issued by the U.S. Preventive Services Task ...
... economics can provide a valuable perspective in addressing ... states an analysis in CMAJ ( ... http://www.cmaj.ca/site/embargo/cmaj111018.pdf . "Understanding and accurately predicting ... if governments wish to increase the supply of ...
... (HealthDay News) --,Women over 50 have more complications -- particularly ... a new study says. The higher rate of complications ... hormone levels, according to the researchers. They looked at ... 2009 and found that the post-surgery infection rate for women ...
Cached Medicine News:Health News:Tools for predicting diabetes exist but are not used, research shows 2Health News:Angioplasty Patients May Be at Risk for Rehospitalization 2Health News:Angioplasty Patients May Be at Risk for Rehospitalization 3Health News:Polarized filter may reduce unnecessary cervical biopsies and surgeries 2Health News:New study supports mammography screening at 40 2Health News:Paying physicians more to get more -- or to get less 2Health News:Older Women Have More Post-Surgical Breast Reduction Infections 2
(Date:5/1/2015)... May 1, 2015   Intarcia Therapeutics, Inc. ... as Vice President, Human Resources, reporting directly to ... As a new key member of the senior leadership ... and Leadership Team to assure the Company advances its ... embeds its core values and its dynamic culture. Another ...
(Date:5/1/2015)... , May 1, 2015 Hitachi Chemical Diagnostics, ... States launch of the ExoComplete™ 96-Well Plate ... easy system for exosome collection to mRNA purification.  The ... Vesicles ("ISEV") Annual Meeting, April 23 – 26, 2015, ... are intended for research use only of molecular biology ...
(Date:5/1/2015)... , May 1, 2015 Following yesterday,s release of ... D, here are five things you need to know: ... market-based structure is unique among government programs. ... D is different than other parts of Medicare and other ... that submit bids to offer prescription drug benefits to enrollees. ...
Breaking Medicine Technology:Intarcia Appoints James P. Brady Vice President, Human Resources 2Intarcia Appoints James P. Brady Vice President, Human Resources 3Intarcia Appoints James P. Brady Vice President, Human Resources 4New Products for Exosome Isolation to mRNA Purification 25 Things to Know About the CMS Part D Data Release 25 Things to Know About the CMS Part D Data Release 3
... The RX600 is a versatile, fully ... range of built-in traction facilities, a powered ... make it extremely versatile too. ,<br.,In fact ... general surgery as it is for traction ...
When You Need Optimal Patient Comfort with Minimal Weight at a Nonunion Site...Demand The OrthoPak Noninvasive Bone Growth Stimulator. , ,Most Appropriate for the Proximal Femur, Metatarsal/Tar...
... OrthoVision Orthopedic and Fracture Table is ... It provides flexible, easy to use, ... and reparative orthopedic procedures. Radiolucent abductor ... post provide exceptional imaging capability. OrthoVision ...
... provides a non-invasive therapy for the ... of fresh fracture healing that you ... daily, or as prescribed by your ... fracture to be sufficiently healed to ...
Medicine Products: