Navigation Links
New Drug to Help Smokers Kick the Habit

The new drug, varenicline or Chantix promises to be more effective than bupropion or Zyban in helping smokers kick the habit In addition it has also shown to promote //longer-lasting abstinence according to the results of three studies published in the Journal of the American Medical Association this week.

Chantix is the first anti-smoking prescription drug in over a decade. It works by stimulating sufficient dopamine release to curb cravings and at the same time blocks the reinforcing effects of smoked nicotine.

The drug is marketed by Pfizer Inc. and received FDA approval in May.

A related editorial however cautions smokers against considering the drug as a panacea for quitting smoking. According to co-author Dr. Robert C. Klesges, from the University of Tennessee in Memphis, "There are some important gastrointestinal side effects and, in the current studies, most people given the drug actually did not quit smoking".

Dr. Karen R. Reeves, from Pfizer Global Research and Development in Groton, Connecticut, and colleagues compared the effects of Chantix against those of Zyban and placebo in two Pfizer-sponsored studies. In a third study, Chantix was tested against placebo in maintaining abstinence from smoking.

The first study involved 1025 people who smoked at least 10 cigarettes per day. After 12 weeks of Chantix an immediate abstinence rate of 44 percent was noted in these people, which was significantly higher than the 29.5 percent and 17.7 percent rates achieved with Zyban and placebo, respectively.

It was noted however that at 1 year the abstinence rate for Chantix was not much different from that of Zyban: 21.9 percent vs. 16.1 percent although it was higher than the 8.4 percent seen with the placebo. Several patients also reported nausea as a side effect of Chantix while Zyban was associated with a high rate of insomnia.

The second study showed a higher abstinence rate at 1 year of about 23 percent with Chantix compared to 14.6 percent with Zyban. 30 percent of the patients, however, did report nausea with Chantix.

In the third study 1210 smokers were involved who remained abstinent for at least 7 days after completing a 12-week course of Chantix. The subjects were randomized to continue the drug for an additional 12 weeks or switch to placebo.

It was found that subjects who remained on Chantix had a continuous abstinence rate from weeks 13 to 52 of 43.6 percent, which was higher than the 36.9 percent rate seen in the placebo group.

According to Klesges although the results are encouraging smokers should not get caught up in the media hype likely to surround this new drug and think that it represents any easy cure for their problem. "There is no such thing as a magic bullet for any condition, let alone one that involves complex human behavior."

Still, as Klesges noted, ‘This drug may be as good as we're going to get in terms of a medical therapy for smoking cessation. There clearly is an addictive component to smoking and the best results are achieved when a medical therapy is combined with a behavioral intervention.’


Related medicine news :

1. Smokers children likely to develop caries
2. Smokers more prone to depression
3. Female Smokers More Prone To Lung Cancer
4. Young Smokers at Increased Risk Of Developing a Heart Attack
5. Women Smokers More Prone To Lung Cancer
6. Creating A Greater Awareness Among Smokers
7. Smokers may differ in their cravings for smoking
8. Trained Counselors Counseling Pregnant Smokers To Quit May Not Work
9. Smokers Avoid Dental Care More Than Others
10. Smokers Face The Risk Of Becoming Blind In Later Life
11. New Vaccination For Smokers To Quit Smoking
Post Your Comments:

(Date:6/25/2016)... ... ... Conventional wisdom preaches the benefits of moderation, whether it’s a matter of indulgence ... high can result in disappointment, perhaps even self-loathing. However, those who set the bar ... from reveals that behind the tendency to set low expectations is ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. Her ... would lash out at his family verbally and physically. , “When something upset him, he ... he would use it. He would throw rocks at my other children and say he ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... Comfort ... the American Cancer Society and the Road To Recovery® program to drive cancer patients ... seniors and other adults to ensure the highest quality of life and ongoing independence. ...
(Date:6/24/2016)... New York, NY (PRWEB) , ... June 24, ... ... lifestyle publication Haute Living, is proud to recognize Dr. Barry M. Weintraub as ... believes that “the most beautiful women in the world, and the most handsome ...
(Date:6/24/2016)... ... June 24, 2016 , ... Venture Construction Group ... Tournament held on June 20th at the Woodmont Country Club at 1201 Rockville ... an organization dedicated to helping service members that have been wounded in battle and ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... LAS VEGAS , June 26, 2016 ... movement to value-based care operating models within the health ... that enable greater financial efficiency , Deloitte offers ... address the key business issues impacting efficient cost optimization: ... alignment , These services facilitate better outcomes and ...
(Date:6/24/2016)... June 24, 2016  Collagen Matrix, Inc., ("Collagen ... and manufacturing of collagen and mineral based medical ... that Bill Messer has joined the ... further leverage the growing portfolio of oral surgery, ... Bill joins the Collagen Matrix executive team ...
(Date:6/24/2016)...   Bay Area Lyme Foundation , collaborating ... for Tick Borne Illness , Harvard Medical School ... Medicine, University of California, Berkeley, and the Veterans ... finalists of Lyme Innovation , the first ... scientists, clinicians, researchers, entrepreneurs, and investors from several ...
Breaking Medicine Technology: