Navigation Links
New Drug For Treating Chronic Shoulder Pain

The patients suffering from chronic shoulder pain were left with only two options previously, either to take Advil or to go for a surgery//, after the safety concerns surrounding Vioxx and other Cox-2 inhibitors were raised. But a research done by Columbia University Medical Center has found that sodium hyaluronate, a drug approved by FDA for treating osteoarthritis of the knee can also be used for treating the shoulder pain.

The study was presented today at the American Academy of Orthopaedic Surgeons annual meeting in Chicago by Theodore Blaine, M.D., assistant professor of orthopaedic surgery at Columbia University Medical Center and an attending surgeon at NewYork-Presbyterian Hospital.

The study showed that in patients with osteoarthritis of the shoulder, sodium hyaluronate was effective in reducing chronic pain by nearly 50 percent. The results were comparable to the 1998 study that led the FDA to approve the drug's use in treating knee pain. The FDA is currently reviewing the results in shoulder pain.

"Chronic shoulder pain is a common problem that can not adequately be treated with existing FDA-approved therapies," said Dr. Blaine, who was the principal investigator of the study. "The results of the trial were very encouraging, and we hope will lead to this drug's approval as an effective therapy for thousands of suffering patients."

According to the National Institute of Musculoskeletal and Skin Diseases, shoulder problems account for about 1.5 million visits to orthopaedic surgeons annually. The pain can be caused by a variety of problems, including osteoarthritis or rotator cuff tears.

Sodium hyaluronate is a vital building block of normal cartilage. It is marketed under the name Hyalgan by Sanofi Aventis.

All of the patients in the study had previously tried nonsurgical clinical interventions - including physical therapy, at least one steroid injection, and various oral pain medicati ons - but the pain persisted. At the beginning of the study patients received an x-ray of the shoulder to confirm the diagnosis of osteoarthritis and rule out fractures or other exclusionary criteria, as well as an MRI to diagnose soft tissue and bony pathology or a tear in the rotator cuff.

The 602 patients who comprised the study population were broken up into three groups. One group received five injections of the drug over six months. A second group received three injections, followed by two saline injections, and the third group received just a placebo of five saline injections.

Throughout the six month trial, the patients were asked to record their level of pain on a scale of one to 100 -- with 100 being the worst pain imaginable. All three groups began with an average baseline score of 65. Patients with osteoarthritis who received sodium hyaluronate saw the greatest decrease in their pain scores, which was reduced to a score of 35 in six months. The patients who received three injections ended up with a pain score of around 37.

The patients who received saline also saw a decrease, to around 43. The improvement in the saline group could be the result of the placebo effect, as well as the possible therapeutic benefit of irrigating the joint. Similar saline results were seen in the study that led to the drug's approval for knee pain.

No safety concerns arose during the study, which is particularly notable given that the patients were older and more likely to be on other medications and have additional diseases. Sixty percent of the patients were taking cardiac medications, approximately 55 percent took Cox-2 inhibitors prior to joining the study, and up to 14 percent were taking medication for diabetes.

Columbia University Medical Center provides international leadership in pre-clinical and clinical research, in medical and health sciences education, and in patient care. The medical center trains future leaders in health care and includes the dedicated work of many physicians, scientists, nurses, dentists, and public health professionals at the College of Physicians & Surgeons, the College of Dental Medicine, the School of Nursing, the Mailman School of Public Health, the biomedical departments of the Graduate School of Arts and Sciences, and allied research centers and institutions. Columbia University Medical Center researchers are leading the discovery of novel therapies and advances to address a wide range of health conditions.

Souce: Newswise
'"/>




Related medicine news :

1. Treating eye pain eases migraine
2. Treating wounds without stitches
3. Treating varicose veins
4. Treating acne with laser
5. Once-Daily Cipro(R) XR for Treating Complicated Urinary Tract Infections
6. Treating Stroke Patients in Rural Areas
7. Free Tissue Transfer Effective in Treating Massive Skin Cancers
8. Treating Blocked Arteries In The Lower Limbs
9. Zinc Supplements Found To Be Effective In Treating Children With ADHD
10. Hormone Leptin Found To Be Effective In Treating Women With Infertility Problems
11. Treating Depression In Children Could Lead To Poor Bone Development
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... NY (PRWEB) , ... October 13, 2017 , ... Ellevate ... people in business to advocate for action towards gender equality at their inaugural Summit ... from around the globe, and reached a social audience of over 3 million. To ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains ... possible to save lost souls in the Philippines. “The Journey: From the Mountains to ... dedicated teacher of the Bible. She has taught all ages and currently teaches a ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company has developed ... consumer and regulatory authorities worldwide. From Children’s to Adults 50+, every formula has ... highest standard. , These products are also: Gluten Free, Non-GMO, Vegan, Soy ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... Hair Restoration, has recently contributed a medical article to the newly revamped ... Dr. Mohebi’s article spotlights the hair transplant procedure known as Follicular Unit ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... the nation's first interactive health literacy software tool, and the Cancer Patient Education ... of cancer patient education, today announce a new strategic alliance. , As ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... Oct. 11, 2017  True Health, a leader ... its effort during National Breast Cancer Awareness month ... risks. Research ... calculated that more than 10 million American women ... in BRCA1 or BRCA2 and have not had testing. ...
(Date:10/5/2017)... 2017  In response to the nationwide opioid ... Surgeons (AAOMS) released prescribing recommendations that urge ibuprofen ... as a first-line therapy to manage a patient,s ... Recognizing the value and importance of ... Prescribing: Acute and Postoperative Pain Management" stresses that ...
(Date:10/2/2017)...  Eli Lilly and Company (NYSE: LLY ... quarter of 2017 on Tuesday, October 24, 2017. Lilly ... with the investment community and media to further detail ... will begin at 9 a.m. Eastern time. Investors, media ... of the conference call through a link that will ...
Breaking Medicine Technology: