Navigation Links
New Drug ALT-711 decreases blood vessel stiffness

A novel drug that breaks down collagen bonds in the body's blood vessels significantly decreases the stiffness of vessels in older people, according to a study conducted by National Institute on Aging (NIA) scientists and others. The finding suggests the medication could be a new treatment for high blood pressure, heart failure, and certain complications of diabetes. The drug, ALT-711, snips bonds or crosslinks created in the arteries and other tissues when glucose attaches to the protein collagen. //

Crosslinks are cable-like structures that inhibit the natural flexibility of collagen strands. They tend to proliferate with age. Crosslinks appear to toughen tissues and may contribute to some of the deterioration associated with aging and diabetes, such as elevated systolic blood pressure, stiff arteries, and impaired kidney function.

The ability to reduce vascular stiffness could have a major influence on reducing deaths from heart disease. For the current study, investigators at nine U.S. clinical centers recruited 93 people over the age of 50 who showed evidence of vascular stiffening, including high systolic blood pressure and pulse pressure of at least 60 mm Hg.

The participants were randomly divided into two groups-those who received daily doses of ALT-711 and those who were given a placebo daily. After 56 days, arterial pulse pressure - the difference between systolic and diastolic blood pressures - was significantly reduced among those taking the drug compared to the placebo group.


'"/>




Page: 1

Related medicine news :

1. Headache decreases appetite
2. Contraceptives decreases Libido
3. Alcohol decreases risk of dementia
4. Cooling decreases heart attack effects
5. Vitamin E decreases high blood pressure in kidney failure
6. Light therapy decreases depression during pregnancy
7. Perceived stress decreases vaccine response
8. Infant receives first bloodless liver transplant
9. Spouses and other partners lower blood pressure says new research
10. H2O - a cure for low blood pressure
11. Uncontrolled blood pressure
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/23/2017)... , ... March 23, 2017 , ... “Beyond and Back”: ... and Back” is the creation of published author Bonetta Rose, a wife, mother and ... lives. , Published by Christian Faith Publishing, Bonetta Rose‘s new book presents actual events ...
(Date:3/23/2017)... ... March 23, 2017 , ... “My Journey Through Heaven”: ... with an infinitely more profound faith of God’s promise of Heaven for His people. ... who spends each day with his wife, three children and six grandchildren living and ...
(Date:3/23/2017)... ... March 23, 2017 , ... “A Respectful ... “A Respectful Response To Atheist Manifesto” is the creation of published author Richard ... Nancy, for sixty years. He holds graduate degrees from Kent State University and ...
(Date:3/23/2017)... ... 23, 2017 , ... “More Corruption”: a simple and strong explanation of the God’s love. ... rulers of Heaven was asked by God to write a book about Him. , She ... because I kept my commitment to the Lord God. They have not walked in my ...
(Date:3/22/2017)... ... 2017 , ... Death anxiety is unconscious and needs understanding and non-judgmental support ... to write the book titled “ As Good as Goodbyes Get ” (published by ... what she was experiencing at the bedside of patients who were dying. The book ...
Breaking Medicine News(10 mins):
(Date:3/22/2017)... MILWAUKEE , March 22, 2017 Serve You ... Custom Prescription Management, Inc. (Serve You), based in ... Order Pharmacy (NEMOP) business, based in Middlebury, Vermont ... positioning ourselves for geographic expansion, so it was perfect timing ... , President and CEO of Serve You. "Like us, NEMOP ...
(Date:3/22/2017)... N.J. , March 22, 2017  CANTEL MEDICAL CORP. ... B. Hansen , President and CEO, will be presenting at ... at the Westin Grand Central Hotel in New ... April 5, 2017 at 3:00 p.m. ET. In addition, management ... A live audio webcast will be available ...
(Date:3/22/2017)... -- Ablation is the minimally invasive therapeutic tissue excision ... from cancerous or diseased tissue removal, to the ... fibrillation and others. The growing adoption of minimally ... and improvise existing ablation technologies for better patient ... is expected to grow at high single digit ...
Breaking Medicine Technology: