Navigation Links
New Compound Offers Hope In Liver Cancer Treatment

The identification of a novel compound, CDDO-Im, shown to possess strong anti-tumor properties in studies conducted on animal models could soon revolutionize the treatment of liver cancer patients. // The compound has been found to increase the intrinsic resistance to carcinogens (cancer causing substances) by enhancing the function of enzymes that remove toxins from the body. Further results about the compound have been published in the journal Cancer Research.

The compound has been found to be active (100 times effective than other anti-tumor compounds) at very small doses. It is hoped that the compound could play an important role in the prevention of cancers associated with inflammation such as lung cancer, liver cancer, prostate cancer and gastric cancer. It can also help in the treatment of asthma, emphysema or other neurodegenerative disorders, linked to inflammation.

The synthetic compound, a derivative of oleanolic acid, belongs to a class of compounds commonly referred to as triterpenoids. Previous studies have established the anti-tumor properties of oleanolic derivatives in animals and humans.

In order to assess the effectiveness of cancer prevention, the researchers treated rats with aflatoxin, a carcinogen, known to cause liver cancer. The rates were treated with 0.1, 0.3, 1.0, 3.0 or 10 micromole doses of CDDO-Im. As much as 85% reduction in the incidence of pre-cancerous lesions could be observed when rats were treated with 0.1 mmol of the compound. This anti-cancer property could be due to associated activation of Nrf2 protein. This protein is believed to play a major role in the protection of body against environmental toxins.

The results of this study have several important clinical applications. First, it could lead to the development of new cancer prevention strategies. Second, it can attenuate the clinical features and provide relief to those suffering from inflammatory diseases. Third, it can pro tect humans from several diseases that can be attributed to a specific environmental agent.


'"/>




Related medicine news :

1. Compound of Broccoli combats breast cancer
2. New Compound Could Strengthen The Effect Of Chemotherapy
3. Breathing Cancer Causing Compounds During Pregnancy Found To Affect Offspring
4. Compound from cottonseed for neck and head cancers
5. Compounds Found In The Vegetable Broccoli Could Have Anti-Cancer Properties
6. Adding Sorghum Compounds To Dietary Supplements May Help Lower Cholesterol
7. Compound In Grapes And Red Wine To Counter Alzheimers Disease
8. Sugars Could Contain Key Cancer Inhibiting Compounds
9. Compound From Cyanobacterium Can Fight Alzheimer’
10. Five New Anti-Inflammatory Compounds Produced By Indian Scientists
11. Compounds in Licorice Can Fight Tooth Decay
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/12/2016)... ... February 12, 2016 , ... For Coast Dental dentist Everet Lake, ... and dental assistant Terrell Moore shortly before 7 a.m. to volunteer at Friday’s Dentistry ... donating their time and skills to help hundreds of uninsured and underinsured people receive ...
(Date:2/12/2016)... ... February 12, 2016 , ... Nearly every health website ... health. These articles generally list between five and 15 foods that should be ... every one of these lists and believes that nutritious eye healthy foods are ...
(Date:2/12/2016)... ... February 12, 2016 , ... US Sport Camps is pleased to announce ... located in Norwalk, serves as the host site and directing the camps is PGA ... have had successful camps in recent years around Des Moines and are fortunate to ...
(Date:2/12/2016)... ... February 12, 2016 , ... The Central Coast Autism Spectrum Center (CCASC) invites teens ... provide a night of fun for teens with and without special needs to gather in ... included at the event. The dance will take place on Saturday, Feb. 13 from 7 ...
(Date:2/12/2016)... Mi (PRWEB) , ... February 12, 2016 , ... Basketball ... unique and integral part of the Peety PoppersTM series, sign language translation is featured ... message of health and wellness in Peety PoppersTM lessons has a sign language translator ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... Ambulances announces its first delivery in the state of ... Emergency Medical Services (EMS) consisting of four vehicles: three ... Emergency Vehicles in Lecanto, FL , USA, ... the latest in Demers, ongoing expansion of sales.  ... --> Benoit LaFortune , Executive Vice President at Demers. ...
(Date:2/12/2016)...  Memorial Hermann Health System has teamed up with ... bring a one-of-a-kind experience to pediatric patients at ... as 360-degree video and Google Cardboard, Howard was able ... giving the patients and their families an unexpected, and ... on video . Memorial Hermann IRONMAN ...
(Date:2/12/2016)... Ontario , Feb. 12, 2016  Aralez Pharmaceuticals ... pharmaceutical company, today announced the Company will ring the Nasdaq ... New York at 4:00 p.m. ... formation of Aralez. Adrian Adams , ... be held 3:50 to 4:00 p.m. ET.  A live ...
Breaking Medicine Technology: