Navigation Links
New Cholesterol gene linked to Alzheimer's

The findings of a new study published in January's Archives of Neurology suggests that a new gene called CYP46 may play a role in some cases of Alzheimer's disease. A variation in the gene, which is involved in the production of an enzyme that helps break down excess cholesterol in the brain, may result in the buildup of cholesterol and a gummy protein// called beta amyloid, in the brain.

Earlier studies have shown that elevated cholesterol levels may raise the risk of Alzheimer's. There is also previous evidence that Alzheimer's is related to variation in another gene called APOE-4, which helps in transporting cholesterol throughout the body. In the new study which involved more than 400 patients with or without Alzheimer's, the CYP46 variant was found in about 40 percent of participants. It was observed in the study that patients with both the CYP46 and APOE-4 variants were almost 10 times more likely to develop the mind-robbing disease than those with neither variation. These patients also had the highest brain levels of beta amyloid. Autopsies of patients with just the CYP46 variant revealed significantly higher levels of beta amyloid deposits than those without the variant.

Dr. Benjamin Wolozin of Loyola University Medical Center in Maywood, said in an accompanying editorial that this and earlier studies suggest that inhibiting cholesterol breakdown in the brain might represent a viable treatment for Alzheimer's.


'"/>




Page: 1

Related medicine news :

1. Low Cholesterol Linked to Severe Depression and Violent Behavior in Men
2. Eating More Often May Help Lower Cholesterol
3. Caution On Use of Cholesterol Drugs
4. High Cholesterol linked to Alzheimer’s diseas
5. Cholesterol Drug Helps After Angioplasty
6. Cholesterol lowering drugs increase neuropathy risk
7. Almonds Improve Cholesterol
8. Cholesterol-lowering therapy benefits older people also
9. Cholesterol lowering drugs aid people after heart transplant
10. Children’s Cholesterol Matter
11. Tea Pill Lowers Cholesterol
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... , ... As health professionals work to improve their approach to healthcare, there ... more than filling out a survey; in many cases health professionals and patients are ... care and research on the importance of active engagement with patients and members of ...
(Date:10/13/2017)... Las Vegas, Nevada (PRWEB) , ... October 13, 2017 , ... ... of 7® Hemp CBD Oil utilizing Purzorb™ technology. Applying the Purzorb™process to full spectrum ... CBD dose required and providing a CBD form that can be easily incorporated into ...
(Date:10/13/2017)... ... , ... Many families have long-term insurance that covers care for a family ... for care if the client has a cognitive impairment diagnosis. , “What this ... often waived, so the benefits from their insurance start immediately,” said Mechell Vieira, owner ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The ... the most popular and least understood books in the Holy Scriptures, Revelation. The Book ... have baffled scholars for centuries. Many have tossed it off as mere rubbish, but ...
(Date:10/13/2017)... , ... October 13, 2017 , ... “America On The ... identity. “America On The Brink” is the creation of published author, William Nowers. ... great-grandchildren. As a WWII veteran, he spent thirty years in the Navy. ...
Breaking Medicine News(10 mins):
(Date:9/28/2017)... WASHINGTON , Sept. 28, 2017 Cohen ... to advance the use of wearable and home sensors ... brain disorders. Early Signal Foundation, a nonprofit organization focused ... populations, will provide an affordable analytical system to record ... ...
(Date:9/25/2017)... PROVIDENCE, R.I. , Sept. 25, 2017 /PRNewswire/ ... immunogenicity assessment, vaccine design, and immune-engineering today announced ... focused on the development of personalized therapeutic cancer ... and has provided exclusive access to enabling technologies ... MSc Eng., MBA will lead EpiVax Oncology as ...
(Date:9/19/2017)... Sept. 19, 2017 HistoSonics, Inc., a venture-backed medical device company developing a non-invasive, ... tissues, announced three leadership team developments today:   ... ... ... Veteran medical device executive Josh Stopek , PhD, ...
Breaking Medicine Technology: