Navigation Links
New Chemistry Approach Promises Less Expensive Drugs

supported the work. "What's particularly exciting to me is the depth and rigor of the analysis that enabled this very creative breakthrough. Equally important, MacMillan has discovered new reactions that will streamline the synthesis of compounds that are relevant to human health."

Most drug molecules that pharmaceutical companies produce can exist in two different forms, which are mirror images of one another. Though both forms of an organic molecule -- known in the chemistry world as "enantiomers" -- have the same chemical formula, their effect on the body can differ dramatically.

"The two enantiomers are like keys with the same number of teeth, but which have different orientation," MacMillan said. "One key fits in with our biology very well, opening the correct doors in our body and helping us to heal. But the other key doesn't fit the same doors because its teeth are in opposing locations."

The two forms are indistinguishable by most modern lab tests, yet our bodies can tell the difference. Where one enantiomer might be the basis for a helpful drug, its mirror image might do nothing for the body, or even damage it.

"This was the problem in the 1960s with the drug phthalidomide," MacMillan said. "One of its enantiomers helped pregnant women overcome morning sickness. Its mirror image, however, caused birth defects."

In the vast majority of cases, the Food and Drug Administration now requires that drug companies create only the beneficial enantiomer during the manufacturing process. While this requirement keeps any of these helpful molecules' "evil twins" from reaching our systems, it also places heavy demands on the drug companies.

Building large quantities of a drug molecule often requires a catalyst, a substance that permits a chemical reaction to take place without itself being affected. Until recently, however most catalysts would create both enantiomers simultaneously, MacMillan said. I
'"/>




Page: 1 2 3 4

Related medicine news :

1. Love And Drug Addiction Share The Same Chemistry
2. The Chemistry Of Sexual Attraction Between Male And Female Elephants
3. Chemistry Over The Counter: Is It Just What The Doctor Ordered?
4. New Dietary Approach To Manage Kidney Stones
5. Approaching through Telemedicine benefits patients
6. Gel Offers A More Targeted Approach
7. New Cost Effective Approach To Promote Sun Protection
8. Treatment Of Brain Aneurysms By A New Non-Surgical Approach
9. A New Approach In Treatment Neurogenic Detrusor Overactivity In Children
10. A New Diagnostic Approach To Pediatric Interstitial Lung Disease
11. Lazy Eye Can Be Effectively Treated By New Approach
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New Chemistry Approach Promises Less Expensive Drugs

(Date:7/2/2015)... , ... July 02, 2015 , ... ... software, announced today a new release of their flagship product, 3D Tooth Atlas, ... Human Dentition quiz section and new tutorial videos. This latest release of the ...
(Date:7/2/2015)... Kan. (PRWEB) , ... July 02, 2015 , ... ... dedicated exclusively to healthcare providers, has been retained to lead a national ... of the top executive search firms in the healthcare industry, B. E. Smith ...
(Date:7/2/2015)... , ... July 02, 2015 , ... ... status of the Gelatin Capsule manufacturers. The report is a valuable source of ... report depicts the global and Chinese market for the Gelatin Capsule industry including ...
(Date:7/2/2015)... ... 02, 2015 , ... Catalent Pharma Solutions, the leading global ... health products, today announced that it has made two key appointments at its ... Manager at Catalent’s Schorndorf facility, which provides large scale, complex oral solid manufacturing ...
(Date:7/2/2015)... ... July 02, 2015 , ... Today, East Liverpool City Hospital announced ... at East Liverpool City Hospital (ELCH). Pam is currently the Chief Nursing Officer at ... of surgery. Pam holds a master’s degree in health care administration as well as ...
Breaking Medicine News(10 mins):Health News:eHuman Digital Anatomy Releases 3D Tooth Atlas version 7.6 2Health News:Nicklaus Children’s Hospital Retains B. E. Smith to Recruit New Chief Operating Officer 2Health News:Nicklaus Children’s Hospital Retains B. E. Smith to Recruit New Chief Operating Officer 3Health News:Gelatin Capsule Market Outlook & Forecast Report 2015-2020 2Health News:Gelatin Capsule Market Outlook & Forecast Report 2015-2020 3Health News:Gelatin Capsule Market Outlook & Forecast Report 2015-2020 4Health News:Catalent Makes Two Key European Appointments in Oral Dose Manufacturing 2Health News:East Liverpool City Hospital Announces New Surgical Center Leadership 2Health News:East Liverpool City Hospital Announces New Surgical Center Leadership 3
... and loses 20 pounds by flooding his body with ... and blood to reach ultimate goal of sublime healthLOS ... CEO/Founder of iZO Cleanze, a comprehensive full-body detox program ... it of toxins, reaches the halfway point of his ...
... in Development of ,Next Generation, Dietary Supplements and Functional ... appointed Dr. Rudi E. Moerck as President & Chief ... CEO duties for Dr. Moerck comes on the heels ... Parry (India) Ltd, Chennai, India) announced last November. In ...
... Early research in animals suggests it might be possible ... appear to prevent noise-induced hearing loss in lab animals, ... finding suggests that it may be possible to create ... hearing loss in humans. , Two studies found that ...
... of Life is excited to announce that the David ... "Golfers drinking VaNu report feeling a higher ... an improved sense of well-being," said David Leadbetter, owner ... to VaNu during a PGA event in late 2008, ...
... 19 Varian Medical,Systems (NYSE: VAR ) today ... Therapy System, which is designed to help doctors to improve,treatments ... doctors,can use higher doses of radiation to control and manage ... , "CE mark is an important ...
... Dentistry - San Diego County,s premiere dental practice (online ... program designed to promote whole-body health at its newest ... Most people despise the dentist - the chemical smells, ... causes many Americans to skip the dentist altogether. But ...
Cached Medicine News:Health News:CEO of iZO Cleanze Completes Day 50 of 100-Day Juice Cleanse 2Health News:Valensa International's Dr. Rudi E. Moerck Appointed CEO 2Health News:A Pill to Prevent Hearing Loss? 2Health News:World-Renowned Golf Instructor David Leadbetter Promotes VaNu 2Health News:Varian Medical Systems Has Received CE Mark for Proton Therapy System 2Health News:Discover Whole Body Wellness Through a Revolutionary - and Natural - Approach to Dental Care 2Health News:Discover Whole Body Wellness Through a Revolutionary - and Natural - Approach to Dental Care 3
(Date:7/2/2015)... Minolta, Inc. (Konica Minolta) ( Tokyo : ... Ltda., an X-ray system equipment manufacturer based in Minas ... healthcare sales company, Konica Minolta Healthcare do ... market investment and growth With ... healthcare technical advancements and efficiencies are required. Aging and ...
(Date:7/2/2015)... ALPINION MEDICAL SYSTEMS Co., Ltd., announced today ... Developed to enhance user experience and patient care in ... produces superb image quality. With advanced imaging technologies, this ... imaging, and shared service applications. Confidence at ... E-CUBE Series, the E-CUBE 15 EX provides advanced women,s ...
(Date:7/2/2015)... July 2, 2015   Wilson Therapeutics AB , ... Hans Schikan to its board of directors. The appointment ... Meeting on June 30. "We are delighted ... Jonas Hansson , CEO of Wilson Therapeutics. "Hans ... we look forward to his contributions to the Company." ...
Breaking Medicine Technology:Konica Minolta Acquires Sawae, Enhancing Digital X-ray Diagnostic Imaging Systems in Brazil 2Konica Minolta Acquires Sawae, Enhancing Digital X-ray Diagnostic Imaging Systems in Brazil 3E-CUBE 15 EX from ALPINION Enhances User Experience and Patient Care 2E-CUBE 15 EX from ALPINION Enhances User Experience and Patient Care 3Wilson Therapeutics Appoints Hans Schikan to its Board of Directors 2
All welded construction for strength and durability. Choice of stainless steel or chrome plated models....
All welded construction for strength and durability. Choice of stainless steel or chrome plated models....
... Motorized tilt, user programmable memory two ... control on both chair sides, solid ... base. Single button folding armrests and ... handle on both chair sides, ergonomically ...
... A practical, comfortable chair for ... seat height is adjustable from ... by use of an independent ... rotatable through 360 and incorporates ...
Medicine Products: