Navigation Links
New Cervical Cancer Test Increases the Detection Rate of Abnormal Cells

Newswise A new computerised screening test for cervical cancer detects more abnormalities than the traditional smear test , according to a study published on bmj.com today.

It could also lead to fewer women needing to be re-tested and might allow for longer intervals in-between testing, says Elizabeth Davey and her colleagues.

The manual screening of conventional pap smears for cervical cancer has been around for decades but liquid-based cytology (LBC) is now replacing it in many countries.

Conventional smears are made by transferring material, taken from the cervix by a collection instrument, directly onto a glass slide. LBC slides are made by rinsing the collection instrument in liquid to produce a suspension, which is processed in a laboratory to produce a single layer of cells.

A recent study published by Guglielmo Ronco in the BMJ found that LBC did not significantly increase the ability to detect moderate (CIN2) or severe abnormalities (CIN3) compared to the conventional smear when both slides were evaluated manually by a cytologist.

In the study published today by Dr Davey, researchers used a computerised reading system, known as a Thin Prep Imager (TPI) to evaluate LBC slides. The programme would highlight any slides which needed further examination. These were looked at by a cytologist.

Samples were taken from 55,164 Australian women. From each single collection, a conventional cytology (CC) sample was made first, followed by a TPI sample.

The most important finding of the study is that the ThinPrep Imager detected 1.3 more cases of high-grade cervical abnormalities per 1,000 women screened than the conventional cytology test.

In Australia, 7.7 cases per 1,000 women screened are currently detected each year through a biennial Pap test screening programme using conventional cytology. Based on the results of this study, introduci ng the ThinPrep Imager would increase detection to 9.0 cases per 1,000 women screened.

Furthermore, fewer slides were found to be unsatisfactory using TPI 1.78% compared to 3.09% with CC. Therefore, fewer women might be recalled for repeat smears than currently occurs if the ThinPrep Imager were introduced into population screening programmes.

The use of the TPI also increased detection of low-grade cell lesions and the researchers conclude this could result in higher rates of further testing.

On the other hand, they say, together with the finding of improved detection of moderate and severe changes (CIN2 and CIN3), it does raise the possibility that the increased detection of abnormalities by TPI might allow longer intervals in between screening.


'"/>




Related medicine news :

1. Virus Level could Predict Cervical Cancer Risk
2. Smallpox Vaccine May Help Fight Cervical Cancer
3. Obesity Increases Risk of Cervical Cancer
4. Reducing The Risk Of Cervical Cancer
5. Improving Fertility In Patients With Cervical Cancer
6. Vaccine for Cervical cancer
7. Cervical spinal injury patients may have more damage left undetected
8. Cervical Cancer Vaccine To Be Developed In India
9. Cervical Cancer Can Now Be Better Handled With Gene Silencing Therapy
10. Cervical Cancer Recurrence Risk Even After Removal Of Pre-Cancerous Cells
11. HPV Vaccines for Cervical Cancer
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... , ... June 25, 2016 , ... As a lifelong ... Cum Laude and his M.D from the David Geffen School of Medicine at UCLA. ... to Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits ... terms of the latter, setting the bar too high can result in disappointment, perhaps ... slow progress toward their goal. , Research from PsychTests.com reveals that ...
(Date:6/24/2016)... ... 24, 2016 , ... June 19, 2016 is World Sickle Cell Observance Day. ... the benefits of holistic treatments, Serenity Recovery Center of Marne, Michigan, has ... , Sickle Cell Disease (SCD) is a disorder of the red blood cells, which ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Global law firm ... 2016 Legal Elite. The attorneys chosen by their peers for this recognition are considered ... Seven Greenberg Traurig Shareholders received special honors as members of this year’s Legal Elite ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway ... call for a minimum wage raise to $12 an hour by 2020 and then adjusting ... restore the lost value of the minimum wage, assure the wage floor does not erode ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 23, 2016 Capricor Therapeutics, ... a biotechnology company focused on the discovery, development ... patient enrollment in its ongoing randomized HOPE-Duchenne clinical ... 50% of its 24-patient target. Capricor expects the ... quarter of 2016, and to report top line ...
(Date:6/23/2016)... PARK RIDGE, Ill. and INDIANAPOLIS ... caliber of students receiving a Lilly Diabetes Tomorrow,s Leaders ... hands. The 2016 scholarship winners, announced today online at ... refused to let type 1 diabetes stand in the ... Lilly Diabetes has supported the Foundation,s scholarship program since ...
(Date:6/23/2016)... -- The vast majority of dialysis patients currently receive ... usually 3 times a week, with treatment times averaging ... equipment preparation and wait time.  This regimen can be ... who are elderly and frail.  Many elderly dialysis patients ... for some duration of time. Residents in ...
Breaking Medicine Technology: