Navigation Links
New Cell Lines Cuts Down the Cost and Time in the Production of Flu Vaccine

Paul Coussens, a professor of animal science and microbiology and molecular genetics, and his colleagues from Michigan State University found that a new cell// line has the ability and potential for growing flu virus.

This is good news because it would result in the production of new human flu vaccines which is cheaper and produced in a shorter period of time.

He identified the new cell line while working on the Marek's disease which is a common chicken disease. This technique is very useful and is not time consuming when compared to the earlier procedure in which the virus strains were grown in fertilized chicken eggs. HepaLife Technologies Inc., a biotechnology company based in Vancouver, has licensed the technology from MSU and plans to produce cell culture-based flu vaccine. ‘We want to proceed as quickly as possible,’ said Harmel Rayat, president of HepaLife. ‘There's no time to waste. Sooner or later the avian flu virus will be in North America. It's not if, it's when.’

‘The recent highly virulent avian flu cases in Asia and fears about a pandemic have highlighted the problems with traditional influenza vaccine production methods, particularly the length of time to produce a new vaccine and the amount of vaccine that can be produced on short notice,’ said Coussens, who also is the director of the MSU Center for Animal Functional Genomics. Building on work done by graduate student Amin Abujoub and assistant professor David Reilly, Coussens and his collaborators found the cell line would grow almost every type of flu virus: avian, swine, equine and human.

In cell culture-based vaccine production, scientists infect cells with flu strains. Then they grow the virus in large vats or bioreactors. The virus is killed and purified to make the vaccine. Growing virus in cell culture could dramatically speed up vaccine production. For the past 50 years, flu vaccines have been made by injecting 11-day-old fertilized chicken eggs with a flu virus strain. The virus grows in the eggs and is then killed and purified to make the vaccine. Each egg is injected with only one virus strain (a typical flu vaccine contains three strains) and produces enough virus for one or two doses. This means that huge numbers of fertilized chicken eggs are needed – 270 million or more – to produce a sufficient vaccine supply for the United States.

The process is time consuming and inflexible because vaccine makers have to order eggs months ahead of time. If there are any problems with the eggs, such as infection by another virus, the entire lot of flu vaccine is lost. Plus, anyone with an egg allergy can't have the vaccine. ‘By growing cell culture-based flu virus, the cost and the time needed to produce the vaccine will be much lower,’ Coussens said. ‘We'll also be able to produce much more vaccine in a smaller space. And the virus that is grown is more pure. People with allergies to eggs are likely to benefit the most because they'll be able to have flu shots without the threat of allergic complications.’

Source: urekalert
'"/>




Related medicine news :

1. Stem Cell Bank In UK Would Require 150 Embryo-Derived Stem Cell Lines
2. Increased Childhood Leukemia Risk If House Is Near Power Lines
3. Therapeutic Monoclonal Antibody Production Is More Profitable Than Small Molecule Drugs
4. Tea Found To Boost Insulin Production And Prevent Cataract
5. Conroy’s May Not Be Permitted To Resume Production Soo
6. Massive Production Of Bird Flu Vaccine To Be Initiated In China
7. Chugai Pharmaceutical To Initiate Domestic Production Of Bird Flu Vaccine
8. Coca Cola To Enhance Production Of Diet Coke
9. Natco Pharma Commences Production At Dehradun Unit
10. ABCB6 Is Key to Production of Heme in Hemoglobin
11. Drug Boosts Platelet Production, Reversing Immune Thrombocytopenic Purpura
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/5/2016)... CA (PRWEB) , ... May ... ... lectures and hands-on exercises, the Wharton Seminars for Business Journalists , ... better understanding of key business and economic issues.  This one-day program at ...
(Date:5/5/2016)... , ... May 05, 2016 , ... LELO ... self-love. Every day, LELO fans reach out via email, social media and on the ... upcoming up: “Is the way I masturbate ‘normal’ or ‘correct’?” , While some methods ...
(Date:5/5/2016)... Indianapolis, IN (PRWEB) , ... May 05, 2016 ... ... employee benefits advisory organization, announces McLaughlin & Smoak Benefits as the latest addition ... & Smoak Benefits has a dedicated team of compliance, wellness, human resources, and ...
(Date:5/5/2016)... Bremerton, WA (PRWEB) , ... May 05, 2016 , ... ... program serving the families of Bremerton, Port Orchard and communities west of Seattle. The ... Lowery, a 12 year local girl who died suddenly due to complications from the ...
(Date:5/5/2016)... ... May 05, 2016 , ... ... grants the most heartfelt wishes of these children. The wishes provide hope ... President and CEO of Make-A-Wish Mississippi, Brent Wilson said, “In 2016, the ...
Breaking Medicine News(10 mins):
(Date:5/4/2016)... Valeritas Holdings, Inc. (OTCQB: VLRX) ... offering (APO). This was accomplished via a reverse merger ... a private placement of approximately 5 million shares of ... Under the terms of the reverse merger, which ... will trade on the OTC Markets under the symbol ...
(Date:5/4/2016)... , May 4, 2016 ... of the  "Global Acute lymphocytic Leukemia Market ... to their offering.       (Logo: ... Acute Lymphocytic Leukemia Market and Competitive Landscape ... Lymphocytic Leukemia pipeline products, Acute Lymphocytic Leukemia ...
(Date:5/3/2016)... 3, 2016  As a teenager, an active and ... which damaged his heart. He continued enjoying sports and ... 2013, Shepherd,s heart was giving out and he was ... 20, 2013, the Mesa, Arizona ... Like a heart transplant, the SynCardia TAH-t is the ...
Breaking Medicine Technology: