Navigation Links
New Cell Lines Cuts Down the Cost and Time in the Production of Flu Vaccine

Paul Coussens, a professor of animal science and microbiology and molecular genetics, and his colleagues from Michigan State University found that a new cell// line has the ability and potential for growing flu virus.

This is good news because it would result in the production of new human flu vaccines which is cheaper and produced in a shorter period of time.

He identified the new cell line while working on the Marek's disease which is a common chicken disease. This technique is very useful and is not time consuming when compared to the earlier procedure in which the virus strains were grown in fertilized chicken eggs. HepaLife Technologies Inc., a biotechnology company based in Vancouver, has licensed the technology from MSU and plans to produce cell culture-based flu vaccine. ‘We want to proceed as quickly as possible,’ said Harmel Rayat, president of HepaLife. ‘There's no time to waste. Sooner or later the avian flu virus will be in North America. It's not if, it's when.’

‘The recent highly virulent avian flu cases in Asia and fears about a pandemic have highlighted the problems with traditional influenza vaccine production methods, particularly the length of time to produce a new vaccine and the amount of vaccine that can be produced on short notice,’ said Coussens, who also is the director of the MSU Center for Animal Functional Genomics. Building on work done by graduate student Amin Abujoub and assistant professor David Reilly, Coussens and his collaborators found the cell line would grow almost every type of flu virus: avian, swine, equine and human.

In cell culture-based vaccine production, scientists infect cells with flu strains. Then they grow the virus in large vats or bioreactors. The virus is killed and purified to make the vaccine. Growing virus in cell culture could dramatically speed up vaccine production. For the past 50 years, flu vaccines have been made by injecting 11-day-old fertilized chicken eggs with a flu virus strain. The virus grows in the eggs and is then killed and purified to make the vaccine. Each egg is injected with only one virus strain (a typical flu vaccine contains three strains) and produces enough virus for one or two doses. This means that huge numbers of fertilized chicken eggs are needed – 270 million or more – to produce a sufficient vaccine supply for the United States.

The process is time consuming and inflexible because vaccine makers have to order eggs months ahead of time. If there are any problems with the eggs, such as infection by another virus, the entire lot of flu vaccine is lost. Plus, anyone with an egg allergy can't have the vaccine. ‘By growing cell culture-based flu virus, the cost and the time needed to produce the vaccine will be much lower,’ Coussens said. ‘We'll also be able to produce much more vaccine in a smaller space. And the virus that is grown is more pure. People with allergies to eggs are likely to benefit the most because they'll be able to have flu shots without the threat of allergic complications.’

Source: urekalert
'"/>




Related medicine news :

1. Stem Cell Bank In UK Would Require 150 Embryo-Derived Stem Cell Lines
2. Increased Childhood Leukemia Risk If House Is Near Power Lines
3. Therapeutic Monoclonal Antibody Production Is More Profitable Than Small Molecule Drugs
4. Tea Found To Boost Insulin Production And Prevent Cataract
5. Conroy’s May Not Be Permitted To Resume Production Soo
6. Massive Production Of Bird Flu Vaccine To Be Initiated In China
7. Chugai Pharmaceutical To Initiate Domestic Production Of Bird Flu Vaccine
8. Coca Cola To Enhance Production Of Diet Coke
9. Natco Pharma Commences Production At Dehradun Unit
10. ABCB6 Is Key to Production of Heme in Hemoglobin
11. Drug Boosts Platelet Production, Reversing Immune Thrombocytopenic Purpura
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/26/2017)... ... May 26, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at ... that is focusing on the Peace Agreements being discussed by President Donald Trump and ... a race to try to speed up peace talks in the continuous battle between ...
(Date:5/26/2017)... ... May 26, 2017 , ... “When the Stars Lead Home”: a poignant story ... published author Laura Weigel Douglas, an avid reader who lives in the Pacific Northwest ... feels like Green Hills Adventure Camp. She couldn’t be more grateful. , Twelve-year old ...
(Date:5/26/2017)... ... ... “Cactus Jack: Against All Odds”: the story of Coach Cactus Jack and the ... is the creation of published author, Walter Hubbard, a retired wildlife and fisheries biologist ... Jane. Walter. Walter and Jane have three adult children and a granddaughter. ...
(Date:5/24/2017)... (PRWEB) , ... May 24, 2017 , ... Dr. Alan ... surgery in New York City. He is known for his distinguished expertise and ... vascular surgery, Dr. Benvenisty holds sub-specialty training in treating renovascular disease and aortic ...
(Date:5/24/2017)... OH (PRWEB) , ... May 24, 2017 , ... Dr. ... and comfortable ClearCorrect orthodontics, with or without a referral. Dr. Kejriwal understands ... why she offers convenient, clear braces in Cincinnati, OH. Patients no longer need to ...
Breaking Medicine News(10 mins):
(Date:5/22/2017)... VALLEY COTTAGE, N.Y. , May 22, 2017 ... natural antiviral treatment Gene-Eden-VIR/Novirin, announces the launch of ... in plain English, the results of a clinical ... after one year treatment with Gene-Eden-VIR/Novirin in individuals ... is important to note that there are no ...
(Date:5/18/2017)... , May 17, 2017  Bayer announced today ... portfolio will be presented at the 53 rd ... (ASCO), taking place June 2-6 in Chicago ... at ASCO span prostate, colorectal, liver and thyroid cancers, ... from the Phase II CHRONOS-1 trial of copanlisib in ...
(Date:5/12/2017)... -- The China and Canada joint tech company Laughing ... energy and detergent, and features a powerful disinfection process. ... machine that washes and sanitizes women,s panties or babies, cloth diapers ... ... not require an external water inlet. ...
Breaking Medicine Technology: