Navigation Links
New Cell Lines Cuts Down the Cost and Time in the Production of Flu Vaccine

Paul Coussens, a professor of animal science and microbiology and molecular genetics, and his colleagues from Michigan State University found that a new cell// line has the ability and potential for growing flu virus.

This is good news because it would result in the production of new human flu vaccines which is cheaper and produced in a shorter period of time.

He identified the new cell line while working on the Marek's disease which is a common chicken disease. This technique is very useful and is not time consuming when compared to the earlier procedure in which the virus strains were grown in fertilized chicken eggs. HepaLife Technologies Inc., a biotechnology company based in Vancouver, has licensed the technology from MSU and plans to produce cell culture-based flu vaccine. ‘We want to proceed as quickly as possible,’ said Harmel Rayat, president of HepaLife. ‘There's no time to waste. Sooner or later the avian flu virus will be in North America. It's not if, it's when.’

‘The recent highly virulent avian flu cases in Asia and fears about a pandemic have highlighted the problems with traditional influenza vaccine production methods, particularly the length of time to produce a new vaccine and the amount of vaccine that can be produced on short notice,’ said Coussens, who also is the director of the MSU Center for Animal Functional Genomics. Building on work done by graduate student Amin Abujoub and assistant professor David Reilly, Coussens and his collaborators found the cell line would grow almost every type of flu virus: avian, swine, equine and human.

In cell culture-based vaccine production, scientists infect cells with flu strains. Then they grow the virus in large vats or bioreactors. The virus is killed and purified to make the vaccine. Growing virus in cell culture could dramatically speed up vaccine production. For the past 50 years, flu vaccines have been made by injecting 11-day-old fertilized chicken eggs with a flu virus strain. The virus grows in the eggs and is then killed and purified to make the vaccine. Each egg is injected with only one virus strain (a typical flu vaccine contains three strains) and produces enough virus for one or two doses. This means that huge numbers of fertilized chicken eggs are needed – 270 million or more – to produce a sufficient vaccine supply for the United States.

The process is time consuming and inflexible because vaccine makers have to order eggs months ahead of time. If there are any problems with the eggs, such as infection by another virus, the entire lot of flu vaccine is lost. Plus, anyone with an egg allergy can't have the vaccine. ‘By growing cell culture-based flu virus, the cost and the time needed to produce the vaccine will be much lower,’ Coussens said. ‘We'll also be able to produce much more vaccine in a smaller space. And the virus that is grown is more pure. People with allergies to eggs are likely to benefit the most because they'll be able to have flu shots without the threat of allergic complications.’

Source: urekalert
'"/>




Related medicine news :

1. Stem Cell Bank In UK Would Require 150 Embryo-Derived Stem Cell Lines
2. Increased Childhood Leukemia Risk If House Is Near Power Lines
3. Therapeutic Monoclonal Antibody Production Is More Profitable Than Small Molecule Drugs
4. Tea Found To Boost Insulin Production And Prevent Cataract
5. Conroy’s May Not Be Permitted To Resume Production Soo
6. Massive Production Of Bird Flu Vaccine To Be Initiated In China
7. Chugai Pharmaceutical To Initiate Domestic Production Of Bird Flu Vaccine
8. Coca Cola To Enhance Production Of Diet Coke
9. Natco Pharma Commences Production At Dehradun Unit
10. ABCB6 Is Key to Production of Heme in Hemoglobin
11. Drug Boosts Platelet Production, Reversing Immune Thrombocytopenic Purpura
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Dickinson Insurance and Financial Services, ... preparation services, is providing an update on a charitable event that began earlier ... is a locally recognized nonprofit that provides shelter and care for animals seeking ...
(Date:10/13/2017)... ... 13, 2017 , ... PurhealthRX , a leading Health and Nutrition Company, ... Purzorb™process to full spectrum CBD oil will revolutionize the rapidly growing CBD market by ... be easily incorporated into liquid products, while reducing costs to end users. , The ...
(Date:10/13/2017)... ... October 13, 2017 , ... The Visiting Nurse Association (VNA) ... a collection of specialty vendors and unique items from across the nation, this holiday-themed ... and wellness services offered by the VNA. The boutique will be open Saturday, ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Agile Software Development, has been awarded a contract by the Center for Medicare ... (BPA) aims to accelerate the enterprise use of Agile methodologies in a consistent ...
(Date:10/12/2017)... ... 12, 2017 , ... Planet Fitness, one of the largest and fastest growing ... open a flagship location in Covington, LA at 401 N. U.S. Highway 190, in ... to Office Depot in the Holiday Square shopping center. Its location allows it to ...
Breaking Medicine News(10 mins):
(Date:10/7/2017)... 2017   Provista, a proven leader in ... in purchasing power, today announced a new resource area ... Newsroom is the online home for case studies, ... bios, news releases, slideshows and events. ... of resources at their fingertips, viewers can also watch ...
(Date:10/4/2017)... Mass. , Oct. 4, 2017 ... of single-use, self-contained, illuminating medical devices, today announced ... National Health Surveillance Agency (or Agência Nacional de ... The first single-use, cordless surgical retractor with integrated ... provides optimal access, illumination and exposure of a ...
(Date:10/2/2017)... Oct. 2, 2017 Halo Labs announces the European launch ... called the HORIZON at MIBio 2017 in Cambridge, U.K ... visible particulate matter in biopharmaceutical samples with unprecedented speed and sensitivity ... novel technique Backgrounded Membrane Imaging. ... The HORIZON subvisible particle analysis system ...
Breaking Medicine Technology: