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New Cardiovascular Risk Prediction Models Developed for Women

etic women includes age, systolic blood pressure, current smoking, total and HDL cholesterol, high sensitivity C-reactive protein (CRP) and parental history of myocardial infarction before age 60.

"In these analyses, large proportions of women with 10-year risk estimates of 5 percent to less than 10 percent or of 10 percent to less than 20 percent based on current ATP-III (Adult Treatment Panel III) risk scores were reclassified at either higher or lower risk of total cardiovascular disease when either of the new algorithms was used," the researchers found.

"We developed, validated and demonstrated highly improved accuracy of two clinical algorithms for global cardiovascular risk prediction that reclassified 40 percent to 50 percent of women at intermediate risk into higher- or lower-risk categories," the authors write. "As 8 to 10 million U.S. women have an ATP-III estimated 10-year risk between 5 percent and 20 percent, application of these data could have an immediate effect on cardiovascular prevention," the authors conclude.

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