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New Blood Thinner Pill - First Potential Alternative to Warfarin in 50 years

en seen in other studies of the drug. Schulman said levels increased in the first four months and then returned to normal without any apparent damage to liver function.

However researchers, said the liver problem is worrisome and needs to be followed and what's going to happen to those liver functions when people are on it for three, or four or five years is still unanswered.

The second study examined whether a higher dose of Exanta would be more effective in preventing blood clots after knee replacement surgery. About 2,300 patients in five countries received either one of two doses of Exanta or warfarin for up to 12 days after surgery.

About 20 percent developed clots in the high-dose group; 25 percent in the lower-dose group; and 28 percent for warfarin. There was no significant difference in bleeding.

In a third study in the journal, researchers reported that a daily injection of the blood thinner Arixtra works as well as standard intravenous heparin in treating blood clots in the lung. Arixtra, also known as fondaparinux, does not require monitoring like heparin, and that can shorten hospital stays.


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