Navigation Links
New Biotech Drugs to Aid in Renal Cell Carcinoma Treatment

Two biotech drugs produced by Bayer AG, Pfizer and Onyx pharmaceuticals are astounding doctors with their effects on decreasing the progression// of metastatic kidney cancer.

The drugs, sunitinib (marketed under brand name Sutent) and sorafenib (brand name Nexavar) have been found to delay the progression of renal cell carcinoma by 3 to 6 months.

Renal cell carcinoma is the most common of all kidney cancers; 90 percent of kidney cancers diagnosed in the US are due to this cancer. It is responsible for 1.5 percent of all cancer deaths and around 30,000 cases of renal cell carcinoma are diagnosed every year.

The standard drugs used are interferon alfa and interleukin-2. Yet these drugs help in only 5 percent of cases where the tumors have spread. Hence the excitement over the new drugs.

Researchers from US, France and Poland, contributed to the results of the study published in the New England Journal of Medicine.

The studies report how sunitinib when given to patients slowed the progression of the disease or development of tumors, to 11 months as against 5 months with interferon alfa. This was tested on 375 cancer patients.

In the case of sorafenib, half of 903 volunteers from 19 countries were put on the drug, while the other half received a placebo. Those who took the drug showed an extra period of around 3 months in delay of tumor growth.

The results were so effective that doctors are now thinking of placing the control patients on the drug.

Yet side effects of the drugs persist and can be severe in some patients. They include skin rashes, diarrhea and increased blood pressure.

Both drugs work by inhibiting the blood flowing to the tumor and hence limiting its growth.

"Kidney cancer has always been regarded as a cancer in which there was no progress," explains the lead author of the sunitinib study, Dr. Robert Motzer from Memorial Sloan-Kettering Cancer Center in Ne w York City. "Based on a better understanding of tumor biology, this new medication (sunitinib) was developed, and it has remarkable activity that has resulted in a complete change in the way we treat this cancer."

Dr. James Brugarolas from the University of Texas Southwestern Medical Center, another researcher, adds,” The two new drugs represent a major step forward in our fight against kidney cancer that was made possible by obtaining a greater understanding of the molecular genetics and biology of the disease. These drugs are clearly effective against the tumor.”
AN
'"/>




Related medicine news :

1. Biotechnology industry expected to grow into a three billion dollar industry by 2002
2. Biotechnology on the lead
3. Panacea Biotech To Market Anthrax Vaccine
4. Commercialization of Biotech Discoveries, An Encouragement For Researchers
5. Biotech drug causing anemia-EPREX
6. Leading Biotech Companies Are Interested In Acquisition Of Smaller Companies
7. Biologicals Transfer Proposal between US and Indian Biotechnology
8. Vical Biotech and NIH jointly develops HIV vaccine
9. Biotechnology Initiatives Planned In Hyderabad
10. Biotech Osiris to go public
11. Western Region Tops in Indian Biotech Growth
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... Brooklyn, NY (PRWEB) , ... June 27, 2016 ... ... is using cutting edge technology to revolutionize the emergency ambulance transport experience for ... Many are aware of how Uber has disrupted the taxi industry through the ...
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements owned by ... to enhance the health of felines. The formula is all-natural and is made from ... the PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract ...
(Date:6/25/2016)... ... 25, 2016 , ... The temporary closing of Bruton Memorial Library on June 21 due to ... a new, often overlooked aspect of head lice: the parasite’s ability to live away from ... common occurrence, but a necessary one in the event that lice have simply gotten out ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, ... at Work award to iHire in recognition of their exemplary accomplishments in worksite health ... annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. Her ... would lash out at his family verbally and physically. , “When something upset him, he ... he would use it. He would throw rocks at my other children and say he ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016 According to a ... (Standard Pen Needles, Safety Pen Needles), Needle Length (4mm, ... Hormone), Mode of Purchase (Retail, Non-Retail) - Trends & ... studies the market for the forecast period of 2016 ... 2.81 Billion by 2021 from USD 1.65 Billion in ...
(Date:6/24/2016)... NAMUR , Belgium , ...  (NYSE MKT: VNRX), today announced the appointment of ... Board of Directors as a Non-Executive Director, effective ... the Company,s Audit, Compensation and Nominations and Governance ... Board, Dr. Futcher will provide independent expertise and ...
(Date:6/23/2016)... -- MedSource announced today that it has selected Datatrial,s ... choice.  This latest decision demonstrates MedSource,s commitment to ... by offering a state-of-the-art electronic data capture (EDC) ... the EDC platform of choice in exchange for ... long been a preferred EDC platform by our ...
Breaking Medicine Technology: