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New Antidotes may Harbour Treatments for Deadliest Poisons

Researchers at Washington University School of Medicine in St. Louis, Missouri, have found two antidotes which, if found safe , may lead to treatments for deadliest poisons like Ricin, cholera toxin, and shiga toxin.

Produced by the deadly strains of E. coli bacteria, these toxins travel backwards through a cell's protein-making pathway, passing through the Golgi network and endoplasmic reticulum before interrupting protein synthesis.

A team of researchers led by Jose Saenz screened 14,400 small molecules for compounds that could halt this journey without disrupting normal cell function.

According to New Scientist magazine, the researchers' work led to the identification of two molecules that may offer treatments for these toxins.


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