Navigation Links
New Angiogenesis Finding May Help Fight Cancer Growth

form the tubes that are the precursors to new blood vessels," Bresnick says. "Then we got excited."

Further tests showed that NK-B could inhibit angiogenesis in four ways. It prevents the production of vascular endothelial growth factor (VEGF), a key stimulator of blood-vessel formation, and also reduces the number of receptor molecules that respond to VEGF. NK-B also slows the movement of endothelial cells, which is necessary to form new vessels, and raises the level of a newly discovered angiogenesis inhibitor.

"It's premature to call it a master switch, but intriguingly, it regulates at least four different processes, each of which individually would be anti-angiogenic," says Bresnick.

Angiogenesis inhibitors, Bresnick observes, are a fast-growing field of medicine. This June, the Food and Drug Administration approved an angiogenesis inhibitor as the first drug that can restore some vision in the more severe ("wet") form of age-related macular degeneration (AMD). Wet AMD occurs when leaky blood vessels form in the retina. Along with a similar growth of new blood vessels in diabetes, it is the major cause of blindness in older adults.

But the "holy grail" of angiogenesis inhibition concerns cancer treatment. Before solid tumors start to grow, they must create a new blood supply, and since adults need angiogenesis only during pregnancy and to heal wounds, blocking angiogenesis could be a promising way to halt tumor growth. Also in June, the FDA approved a compound that inhibits VEGF for treating colon cancer, the second-leading cause of cancer death in the United States. The VEGF-inhibitor reduces the formation of blood vessels, helping starve tumors.

But angiogenesis regulation is a two-way street, and there are some diseases in which it might be desirable to stimulate angiogenesis. The new research shows that the NK-B system can work both ways: Reducing inhibition seems to increase angiogenesis.


'"/>




Page: 1 2 3 4

Related medicine news :

1. Role Of MicroRNAs In Angiogenesis Researched
2. A Combination Of Drugs Used For Anti-Angiogenesis And Apoptosis More Effective
3. Anti-fungal Drug Block Angiogenesis
4. Finding relief from Excruciating Headaches a challenge
5. Latest Findings On The Deadly Disease - SARS
6. New Findings Could Reduce The Extent Of Spinal Cord Injuries
7. Surprising Cystic Fibrosis Finding That Could Be A Helpful Treatment Option
8. New Findings for Repeated Miscarriages
9. Finding The Key To Weight Loss!
10. Internet Helps Patients In Finding Info About Their Childrens Health Conditions
11. How Healthy Are Herbal Products? US Findings.
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New Angiogenesis Finding May Help Fight Cancer Growth

(Date:11/26/2014)... Rosa, California (PRWEB) November 26, 2014 ... making never before seen reductions in prices of their ... and Liposomal Vitamin D3 . Discounts of ... , GI for Life’s proprietary ColoVite supplement ... board-certified gastroenterologists to promote colon health. One easy-to-take colon ...
(Date:11/26/2014)... ISI Telemanagement Solutions, Inc., a ... award the 2014 Lync Pioneer Award ... as a great honor to ISI, who continues ... Specifically, ISI offers an integrated collaboration reporting and ... including voice, video, Lync IM, and conferencing. ...
(Date:11/26/2014)... Medical suction and vacuum products have a ... score represents steady growth in the price of medical ... a result of swelling demand for healthcare services and ... considered nondiscretionary. IBISWorld market research analyst, Anna Son, says, ... of flexibility, given the low level of price volatility ...
(Date:11/26/2014)... 26, 2014 Louisiana Back Institute, ... specialists in minimally invasive spine surgery, announces today ... the rapidly growing provider network of orthopedic spine ... coincides with the network’s continuing success providing the ... Louisiana residents who are suffering from orthopedic spine ...
(Date:11/26/2014)... One of the most important and ... in her life is choosing the ideal wedding dress ... ladies to purchase high quality outfits. Today, BellasDress.com has ... now can pick their suitable bridesmaid gowns here at ... make ladies look scintillating and highlight all their most ...
Breaking Medicine News(10 mins):Health News:GI For Life Slashes Prices by 40% on Liposomal Vitamin D3 and ColoVite Colon Health Formula for a Limited Time 2Health News:ISI Telemanagement Solutions, Inc. has been Awarded the 2014 Microsoft Lync Pioneer Award 2Health News:Medical Suction & Vacuum Products Procurement Category Market Research Report from IBISWorld has Been Updated 2Health News:Medical Suction & Vacuum Products Procurement Category Market Research Report from IBISWorld has Been Updated 3Health News:Medical Suction & Vacuum Products Procurement Category Market Research Report from IBISWorld has Been Updated 4Health News:Louisiana Back Institute Welcomes Dr. K. Samer Shamieh into Medical Provider Network 2Health News:Royal Blue Bridesmaid Dresses Now Are Available for Christmas at BellasDress.com 2
... a yeast-based in vitro bioassay for steroid hormones ... treatment of epilepsy and bipolar disorder, is an ... is associated with a high prevalence of reproductive ... researchers examined the widely used anti-convulsants valproate (VPA) ...
... James Smith, a former psychiatric patient has been jailed for ... October last year in a Glasgow's Pollok Park. , ... // released from a psychiatric hospital where a judge had ... ,Stuart Robertson, a father of three from Glasgow, befriended ...
... and you'll see that lots of middle-aged men are losing their ... turns out, reports AP. , ,A British company, for example, ... hairs than they had before, thanks to an early test of ... testing a similar approach next year., ,Other scientists are tracking ...
... women consuming over eight cups of coffee a day risk ... fetal death was twice as likely among heavy coffee drinkers ... coffee., ,Adjusting for other risk factors weakened the association ... risk of fetal death, Dr. Bodil Hammer Bech of the ...
... hints at the evidence that COPAXONE? (glatiramer acetate ... induced neuronal metabolic recovery in patients with relapsing ... (glatiramer acetate injection) is a selective MHC class ... of the frequency of relapses in relapsing remitting ...
... New findings that are being presented during the American ... in Philadelphia, Pennsylvania, say that women are not being ... trials. Through analyses of the recently conducted renal trials ... this may be the reason why the US Food ...
Cached Medicine News:Health News:Man Bludgeons Friend, Gets Life Term 2Health News:Scientists Seek New Ways To Grow Hair On Bald Pates 2Health News:Scientists Seek New Ways To Grow Hair On Bald Pates 3Health News:Scientists Seek New Ways To Grow Hair On Bald Pates 4Health News:Coffee In Pregnancy May Be Risky: Study 2Health News:Help at hand for RRMS patients 2
(Date:11/26/2014)... , Nov. 26, 2014 / -- China Nepstar Chain Drugstore ... a leading retail drugstore chain in China ... stores, today announced the appointment of Ms. Rebecca ... effective immediately. Ms.Zhang has over 20 ... Nepstar in March 1999. Prior to Ms. Zhang,s appointment ...
(Date:11/24/2014)... , Nov. 24, 2014 Juno Therapeutics ... Therapy Designation to the company,s JCAR015 chimeric antigen ... treatment of relapsed or refractory B-cell acute lymphoblastic ... Memorial Sloan Kettering Cancer Center, where Phase 1 ... "The FDA,s action is important news for patients ...
(Date:11/24/2014)...  Relmada Therapeutics, Inc. (OTCQB: RLMD), a clinical-stage company ... announced today that Sergio Traversa , chief executive ... "MAIN Event" Micro-Cap Growth Conference on Wednesday, December 3, ... Sunset Bel Air Hotel, which is located at 11461 ... . The presentation is scheduled for 8:30 ...
Breaking Medicine Technology:China Nepstar Chain Drugstore Appoints Ms. Rebecca Yingnan Zhang as Chief Operating Officer 2China Nepstar Chain Drugstore Appoints Ms. Rebecca Yingnan Zhang as Chief Operating Officer 3Juno T Cell Therapy For Leukemia Granted FDA Breakthrough Therapy Designation 2Juno T Cell Therapy For Leukemia Granted FDA Breakthrough Therapy Designation 3Relmada Therapeutics To Present At LD MICRO Conference 2
... versatile model angulates for vascular procedures. ... height of the support leg, which ... or double tee foot. Add up ... and stability. A convenient bracket is ...
The Biomet® CHS is indicated for intertrochanteric, subtrochanteric and basilar neck fractures of the proximal femur....
... complete orthopedic trauma procedures. Part of ... orthopedic trauma table top provides a ... patient positioning and provides for skin ... procedures: hip pinnings; femur, supine or ...
... Field (PEMF) bone growth stimulation delivered by ... long bone and small bone nonunions. Physio-Stim ... brace, or clothing without lessening its effectiveness. ... compact, lightweight unit including success rates as ...
Medicine Products: