Navigation Links
Neurotransmitter That can Yield New Insights in the Fight Against Diabetes Identified

Neuroscientists at the University of Southern California have identified a chemical that can carry the electrical signal that alerts the brain to low blood sugar levels .

The key to the new finding, which is expected to yield new insights in the fight against diabetes, is the neurotransmitter norepinephrine.

According to the researchers, the chemical travels from the hindbrain, which receives warnings of low glucose levels from the body, to the paraventricular hypothalamus, which authorises the consumption of energy stores to replace the missing sugars.

"There's a huge interest in how the body senses glucose," said Alan Watts, director of the Neuroscience Research Institute at USC and a co-author of the study, which has been published in the Journal of Neuroscience.

"How that information is processed by the brain is really a hot current topic," he added.

Arshad Khan, a research assistant professor at the university, says that knowing how neurons relay hypoglycemia warnings is critical to understanding the overall glucose sensing mechanism in the brain.

"That's why I'm interested in this system, because it's very poorly understood," Khan said.

"If we don't know how an automobile's fuel system works to begin with, then how can we expect to fix one when it is not burning fuel appropriately," he added.

During the study, a group of animals were injected with insulin to drop their blood sugar levels, while another group was injected with norepinephrine directly into the paraventricular nucleus.

The researchers then compared brain tissue sections from both groups of animals, and examined their blood samples for the presence of hormones released by paraventricular nucleus activity.

The same paraventricular neurons lit up in both sets of animals, and the animals displayed similar increases in hormone levels, suggesting that norepine phrine plays a role in transmitting the hypoglycemia warning.

"Norepinephrine is capable of activating these signals just like hypoglycemia does," Khan said.

He insists that norepinephrine is not only sufficient but necessary for conveying hypoglycemia signals from the hindbrain.


'"/>




Related medicine news :

1. $1.5 Million Grant to Yale for Narcolepsy-Neurotransmitter Study
2. A Reduction In Calories Found To Yield More Benefits
3. Bone Marrow Cells Could Yield A New Lease of Life
4. Operating on a Beating Heart Yields Better Results For Blocked Heart Arteries
5. Fight the Flab Competition Yields Great Results
6. Exercise Combined with Dialysis Yields Better Results
7. Sleeping Computers Yield Clues About Genetic Disorders
8. Government Accused Of Yielding NHS To Outside Interests
9. Kyphoplasty Yields Good Long-Term Improvement for Spinal Fractures
10. MRI Development Yields Breakthrough in Diagnosis of Liver Fibrosis
11. Cellular Pathway Yields Potential New Weapon in Vaccine Arsenal
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits ... terms of the latter, setting the bar too high can result in disappointment, perhaps ... slow progress toward their goal. , Research from PsychTests.com reveals that ...
(Date:6/24/2016)... Michigan (PRWEB) , ... June 24, 2016 , ... June ... about the dangers associated with chronic pain and the benefits of holistic treatments, ... individuals who are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is ...
(Date:6/24/2016)... ... ... Global law firm Greenberg Traurig, P.A. announced that 20 Florida attorneys are recognized ... this recognition are considered among the top 2 percent of lawyers practicing within the ... this year’s Legal Elite Hall of Fame: Miami Shareholders Mark D. Bloom, Burt ...
(Date:6/24/2016)... ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief Products, ... minimum wage raise to $12 an hour by 2020 and then adjusting it yearly to ... value of the minimum wage, assure the wage floor does not erode again, and make ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Haute ... Dr. Barry M. Weintraub as a prominent plastic surgeon and the network’s newest ... world, and the most handsome men, look naturally attractive. Plastic surgery should be ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Research and Markets has announced the addition of the ... report to their offering. ... failure, it replaces the function of kidneys by removing the ... the treatment helps to keep the patient body,s electrolytes such ... Increasing number of ESRD patients & substantial healthcare expenditure on ...
(Date:6/23/2016)... June 23, 2016  In a startling report released today, ... residents by lacking a comprehensive, proven plan to eliminate prescription opioid ... ranking of how states are tackling the worst drug crisis in ... states – Kentucky , New Mexico ... . Of the 28 failing states, three – ...
(Date:6/23/2016)... LOS ANGELES , June 23, 2016 /PRNewswire/ ... (NASDAQ: CAPR ), a biotechnology company ... first-in-class therapeutics, today announced that patient enrollment in ... progrEssion in Duchenne) has exceeded 50% of its ... its enrollment in the third quarter of 2016, ...
Breaking Medicine Technology: