Navigation Links
Neurotransmitter That can Yield New Insights in the Fight Against Diabetes Identified

Neuroscientists at the University of Southern California have identified a chemical that can carry the electrical signal that alerts the brain to low blood sugar levels .

The key to the new finding, which is expected to yield new insights in the fight against diabetes, is the neurotransmitter norepinephrine.

According to the researchers, the chemical travels from the hindbrain, which receives warnings of low glucose levels from the body, to the paraventricular hypothalamus, which authorises the consumption of energy stores to replace the missing sugars.

"There's a huge interest in how the body senses glucose," said Alan Watts, director of the Neuroscience Research Institute at USC and a co-author of the study, which has been published in the Journal of Neuroscience.

"How that information is processed by the brain is really a hot current topic," he added.

Arshad Khan, a research assistant professor at the university, says that knowing how neurons relay hypoglycemia warnings is critical to understanding the overall glucose sensing mechanism in the brain.

"That's why I'm interested in this system, because it's very poorly understood," Khan said.

"If we don't know how an automobile's fuel system works to begin with, then how can we expect to fix one when it is not burning fuel appropriately," he added.

During the study, a group of animals were injected with insulin to drop their blood sugar levels, while another group was injected with norepinephrine directly into the paraventricular nucleus.

The researchers then compared brain tissue sections from both groups of animals, and examined their blood samples for the presence of hormones released by paraventricular nucleus activity.

The same paraventricular neurons lit up in both sets of animals, and the animals displayed similar increases in hormone levels, suggesting that norepine phrine plays a role in transmitting the hypoglycemia warning.

"Norepinephrine is capable of activating these signals just like hypoglycemia does," Khan said.

He insists that norepinephrine is not only sufficient but necessary for conveying hypoglycemia signals from the hindbrain.


Related medicine news :

1. $1.5 Million Grant to Yale for Narcolepsy-Neurotransmitter Study
2. A Reduction In Calories Found To Yield More Benefits
3. Bone Marrow Cells Could Yield A New Lease of Life
4. Operating on a Beating Heart Yields Better Results For Blocked Heart Arteries
5. Fight the Flab Competition Yields Great Results
6. Exercise Combined with Dialysis Yields Better Results
7. Sleeping Computers Yield Clues About Genetic Disorders
8. Government Accused Of Yielding NHS To Outside Interests
9. Kyphoplasty Yields Good Long-Term Improvement for Spinal Fractures
10. MRI Development Yields Breakthrough in Diagnosis of Liver Fibrosis
11. Cellular Pathway Yields Potential New Weapon in Vaccine Arsenal
Post Your Comments:

(Date:11/27/2015)... Rosa, CA (PRWEB) , ... November 27, 2015 , ... ... Northern California Medical Associates, Inc. and Dr. Tucker Bierbaum with Emergency Medicine at ... meeting. They observed that both STEMI and Sepsis conditions present in similar ways and ...
(Date:11/26/2015)... (PRWEB) , ... November 26, 2015 , ... Inevitably when ... Many customers choose to buy during the Black Friday and Cyber Monday ... don’t need to search the Internet high and low to find the best massage ...
(Date:11/26/2015)... ... November 26, 2015 , ... Jobs in hospital medical laboratories ... and offered by healthcare staffing agency Aureus Medical Group . These ... October 2015 among those searching for healthcare jobs through the company’s website, ...
(Date:11/26/2015)... ... November 26, 2015 , ... ... consultation, has collaborated with Women’s Web – an online resource for Indian ... on mental and emotional well-being relationship, life balance, stress, professional development, and ...
(Date:11/25/2015)... ... 25, 2015 , ... The holiday season is jam-packed with ... palates of attendees is of the utmost importance. Whether you are cooking at ... these recipes a try this holiday season. , Turkey Croquettes , ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... , Nov. 25, 2015  The American ... and Gynecologists (ACOG), and the March of Dimes ... Protecting Our Infants Act of 2015 ... number of newborns born exposed to drugs, such ... the bill,s introduction, all three organizations have worked ...
(Date:11/25/2015)... On Tuesday, November 24, 2015, the ... Wright Medical Technology, Inc. for product liability and ... implant device, awarded $11 million in favor of ... and three days of deliberations, the jury found ... designed and unreasonably dangerous, and that Wright Medical ...
(Date:11/25/2015)... AVIV, Israel , November 25, 2015 ... (NASDAQ: KTOV ) (TASE: KTOV), a biopharmaceutical company ... simultaneous treatment of various clinical conditions, today announced the ... 3,158,900 American Depository Shares ( ADSs ), each representing ... purchase up to 3,158,900 ADSs. The ADSs and warrants ...
Breaking Medicine Technology: