Navigation Links
Neurotransmitter That can Yield New Insights in the Fight Against Diabetes Identified

Neuroscientists at the University of Southern California have identified a chemical that can carry the electrical signal that alerts the brain to low blood sugar levels .

The key to the new finding, which is expected to yield new insights in the fight against diabetes, is the neurotransmitter norepinephrine.

According to the researchers, the chemical travels from the hindbrain, which receives warnings of low glucose levels from the body, to the paraventricular hypothalamus, which authorises the consumption of energy stores to replace the missing sugars.

"There's a huge interest in how the body senses glucose," said Alan Watts, director of the Neuroscience Research Institute at USC and a co-author of the study, which has been published in the Journal of Neuroscience.

"How that information is processed by the brain is really a hot current topic," he added.

Arshad Khan, a research assistant professor at the university, says that knowing how neurons relay hypoglycemia warnings is critical to understanding the overall glucose sensing mechanism in the brain.

"That's why I'm interested in this system, because it's very poorly understood," Khan said.

"If we don't know how an automobile's fuel system works to begin with, then how can we expect to fix one when it is not burning fuel appropriately," he added.

During the study, a group of animals were injected with insulin to drop their blood sugar levels, while another group was injected with norepinephrine directly into the paraventricular nucleus.

The researchers then compared brain tissue sections from both groups of animals, and examined their blood samples for the presence of hormones released by paraventricular nucleus activity.

The same paraventricular neurons lit up in both sets of animals, and the animals displayed similar increases in hormone levels, suggesting that norepine phrine plays a role in transmitting the hypoglycemia warning.

"Norepinephrine is capable of activating these signals just like hypoglycemia does," Khan said.

He insists that norepinephrine is not only sufficient but necessary for conveying hypoglycemia signals from the hindbrain.


'"/>




Related medicine news :

1. $1.5 Million Grant to Yale for Narcolepsy-Neurotransmitter Study
2. A Reduction In Calories Found To Yield More Benefits
3. Bone Marrow Cells Could Yield A New Lease of Life
4. Operating on a Beating Heart Yields Better Results For Blocked Heart Arteries
5. Fight the Flab Competition Yields Great Results
6. Exercise Combined with Dialysis Yields Better Results
7. Sleeping Computers Yield Clues About Genetic Disorders
8. Government Accused Of Yielding NHS To Outside Interests
9. Kyphoplasty Yields Good Long-Term Improvement for Spinal Fractures
10. MRI Development Yields Breakthrough in Diagnosis of Liver Fibrosis
11. Cellular Pathway Yields Potential New Weapon in Vaccine Arsenal
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/24/2016)... ... ... June 19, 2016 is World Sickle Cell Observance Day. In an effort to ... treatments, Serenity Recovery Center of Marne, Michigan, has issued a pain management ... (SCD) is a disorder of the red blood cells, which can cause episodes of ...
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, ... Elite. The attorneys chosen by their peers for this recognition are considered among the ... Traurig Shareholders received special honors as members of this year’s Legal Elite Hall of ...
(Date:6/24/2016)... Rhinebeck, NY (PRWEB) , ... June 24, 2016 , ... Topical BioMedics, Inc, makers of ... of companies that call for a minimum wage raise to $12 an hour by 2020 ... wage. This will restore the lost value of the minimum wage, assure the wage floor ...
(Date:6/24/2016)... New York, NY (PRWEB) , ... June 24, ... ... lifestyle publication Haute Living, is proud to recognize Dr. Barry M. Weintraub as ... believes that “the most beautiful women in the world, and the most handsome ...
(Date:6/24/2016)... ... June 24, 2016 , ... National recruitment firm Slone ... executive with extensive sequencing and genomics experience, as Vice President of North American Capital ... will be responsible for leading the sales team in the commercialization of the HTG ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , Belgium , June ... MKT: VNRX), today announced the appointment of Dr. ... of Directors as a Non-Executive Director, effective June ... Company,s Audit, Compensation and Nominations and Governance Committees.  ... Dr. Futcher will provide independent expertise and strategic ...
(Date:6/23/2016)... -- Any dentist who has made an implant supported denture ... of them do not even offer this as a viable ... costs involved. And those who ARE able to offer that ... cost that the majority of today,s patients would not be ... , founder of Dental Evolutions Inc. and inventor of Implanova ...
(Date:6/23/2016)... Research and Markets has announced the addition of the ... to 2022" report to their offering. ... financial data derived from varied research sources to present unique ... on the market during the next five years, including a ... markets, regional and country level analysis. The report provides a ...
Breaking Medicine Technology: