Navigation Links
Neural Basis of Anxiety: Newer Insights

People suffering from anxiety tend to interpret confusing situations or those that may possibly be dangerous, as intimidating. Italian researchers from the Mouse Biology Unit of the European Molecular Biology Laboratory (EMBL), have now uncovered the neural basis for such anxiety behaviour in mice.

Their report, in the current issue of Nature Neuroscience, states that crucial roles played by a receptor for the messenger serotonin and a neural circuit involving a brain region called the hippocampus, is responsible for mediating fear responses in ambiguous situations.

A mouse that has learned that a certain cue, for example a tone, is always followed by an electrical shock comes to associate the two and freezes with fear whenever it hears the tone even if the shock is not delivered. But in real life the situation is not always so clear; a stimulus will only sometimes be followed by a threat while other times nothing might happen. Normal mice show less fear towards such ambiguous cues than to clearly threatening stimuli.

A team of researchers led by Cornelius Gross at the EMBL Mouse Biology Unit now discovered that this response to ambiguous stimuli requires a specific receptor molecule for serotonin, a signal many brain cells use to communicate. Mice that lack the serotonin receptor 1A have problems processing ambiguous stimuli and react to them with full-fledged fear responses. The cause is wrongly connected cells in their brains. Serotonin signalling is very important for brain development and if the receptor 1A is missing, defects arise in the wiring of the brain that affect the behaviour of mice later on in life.

"In humans serotonin signalling has been implicated in disorders including depression and anxiety and like our mice patients suffering from these conditions also overreact to ambiguous situations," Gross says. "The next step was to identify the brain regions that are responsible for such complex fea
'"/>




Page: 1 2

Related medicine news :

1. Gamma Knife Offers New Hope For Trigeminal Neuralgia Patients
2. Botox Relieves Neuralgic Pain
3. Fetal Neural Grafts Improves Motor and Cognitive Function in Huntington Patients
4. A boon to the paralyzed -Brain Gate Neural Interface System
5. Research Reveal A New Angle On Neural Circuits.
6. Neural Stem Cells Reduce Parkinsons Symptoms in Monkeys
7. Genetics Might BE The Basis For Chronic Fatigue Syndrome
8. Molecular Basis Of ALS Found
9. Biological Basis for Homosexuality
10. Biological Basis Behind a Couch Potato
11. Basis for Nerve fiber Damage in Multiple Sclerosis Discovered
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Neural Basis Anxiety Newer Insights

(Date:9/21/2014)... Best Cheap Hosting USA, one of the ... and GreenGeeks are the best Reseller hosting suppliers in ... hosting supplier. Actually, these companies have outperformed their competitors ... People can get the best web hosting at affordable ... to the manager, reseller hosting is a very popular ...
(Date:9/21/2014)... 2014 Discount-Dress.com, a company ... recently announced its decision to implement a new shopping ... for ladies across the world. Furthermore, the company has ... ladies. , The new items come in fashionable ... prices, up to 56 percent off. "We are happy ...
(Date:9/21/2014)... Originally approved by the Food and ... propionate) is a synthetic ICS therapy with potent ... treatment of asthma prophylactically in children and adults. ... and HFA, which received the FDA approval in ... propionate, can bind to glucocorticoid receptors with high ...
(Date:9/21/2014)... 2014 Market Research Report ... Industry, 2009-2019 is a professional and in-depth ... (CAS 49562-28-9) industry. The report firstly reviews ... including its classification, application and manufacturing technology.The ... manufacturers of Fenofibrate (CAS 49562-28-9) listing their ...
(Date:9/21/2014)... To accommodate the ever-growing customer base, Angeldress.co.uk decided to ... Recently, the company has unveiled its 2014 vintage ... wedding gowns, Angeldress.co.uk wants to make sure that all ... way. Its high quality vintage wedding outfits are now ... 62% off. , Online shopping is becoming more and ...
Breaking Medicine News(10 mins):Health News:Best Cheap Hosting USA Announces The Best Reseller Hosting Suppliers In 2014 2Health News:Discount-Dress.com Implements A New Shopping Cart Software And Provides New Beach Wedding Dresses 2Health News:Flovent Asthma Market Sales & SWOT Analysis and Forecasts to 2023 in New Report Available at LifeScienceIndustryResearch.com 2Health News:Flovent Asthma Market Sales & SWOT Analysis and Forecasts to 2023 in New Report Available at LifeScienceIndustryResearch.com 3Health News:Flovent Asthma Market Sales & SWOT Analysis and Forecasts to 2023 in New Report Available at LifeScienceIndustryResearch.com 4Health News:Fenofibrate Industry Global and Chinese Analysis for 2014-2019 Now Available at LifeScienceIndustryResearch.com 2Health News:Fenofibrate Industry Global and Chinese Analysis for 2014-2019 Now Available at LifeScienceIndustryResearch.com 3Health News:Fenofibrate Industry Global and Chinese Analysis for 2014-2019 Now Available at LifeScienceIndustryResearch.com 4Health News:Angeldress.co.uk Launches New Range Of 2014 Vintage Wedding Dresses In Its Online Store 2
... acids help new moms fight depression, according to a new ... Journal. ,"Depression in new mothers is common ... percent of postpartum women. In some high-risk populations, the percentage ... percent. Since depression has devastating effects on both mother and ...
... the home clearly raise the risk of the allergic sensitisation ... older children , however, the influence of the environment at ... This is the conclusion reached by scientists from the GSF ... ,The study published by Chih-Mei Chen et ...
... gay governor, James E. McGreevy appears to be knocking on ... in the news for the right reasons. He has ... ,Former Gov. James E. McGreevy, who was brought up ... religion on Sunday at St. Bartholomew's Church in New York. ...
... of IT students here have developed a device that can enable ... ,Called 'E-Netra', it costs Rs.2,000-3,000 and it reads texts through ... heard through earphones. ,Right now it can only ... in Braille script. ,The Agra College team that took ...
... the information furnished by Indira Gandhi National Open University ... Parliament/State legislature or deemed to be university can ... norms and guidelines laid down by the Distance Education ... meeting held on March 23, 2007 had resolved that ...
... from 105 countries met Friday to formally adopt a 24-page ... global warming after five days of heated debate to reaching ... at 3:30 a.m. Friday," said Carloa Traverso Saibante, information officer ... ,Once the IPCC report is formally adopted, it will ...
Cached Medicine News:Health News:Breastfeeding and Omega-3 Fatty Acids Help New Moms Fight Depression 2Health News:Cats at Home Poses Allergy Risk in Young Children 2Health News:Climate Talks Reach Consensus in Bangkok 2
(Date:9/20/2014)... , Sept. 20, 2014 /CNW/ - The issue: Mylan ... recalling all lots of its Mylan-Nitro Spray 0.4 mg/metered dose ... part of the pump component. A missing ... of nitroglycerin to the patient. This defect may lead patients ... they are unable to access it. Not receiving nitroglycerin could ...
(Date:9/19/2014)... CHAPEL HILL, N.C. , Sept. 19, 2014 ... critical role in forging relationships with key opinion ... the market and competition. Despite the critical nature ... has created many challenges, including altering the landscape ... According to research, the oversight ...
(Date:9/19/2014)... -- Harwood Feffer LLP ( www.hfesq.com ) is investigating ... BioPharma, Inc. ("PDL" or the "Company") (Nasdaq: ... fiduciary duties to shareholders or violated the federal securities ... disclosed: "On September 11, 2014, [PDL] was orally notified ... LLP ("EY"), that it was resigning effective September 11, ...
Breaking Medicine Technology:Advisory - Mylan Pharmaceuticals recalling nitroglycerin spray due to defective pump 2Role of Medical Science Liaisons Shifting in Healthcare Industry 2Harwood Feffer LLP Announces Investigation of PDL BioPharma, Inc. 2
... 2011 Volcano Corporation (NASDAQ: VOLC ), ... and therapy guidance tools designed to enhance the treatment ... it will be participating in two upcoming investor conferences. ... participate in the Stifel Nicolaus Healthcare Conference 2011. The ...
... Sept. 1, 2011 /PRNewswire-Asia/ -- China Botanic Pharmaceutical ... Botanic" or the "Company"), a developer, manufacturer and ... medicines ("TCM") in China, today announced that the ... a key research laboratory ("the laboratory") in cooperation ...
Cached Medicine Technology:Volcano Corporation Announces Presentations at Upcoming Investor Conferences 2China Botanic Pharmaceutical Enters into Research Cooperation with Key Laboratory of Forest Plant Ecology 2China Botanic Pharmaceutical Enters into Research Cooperation with Key Laboratory of Forest Plant Ecology 3
... guide is designed for accuracy and for ... "point" or "elbow" aimers and also between ... the tibial tunnel. The system is easy ... the reproducibility and accuracy gained from rigidity ...
The Pinn-ACL Guide can be used to create tibial tunnels of known lengths with a variable angle adjustment of 35 to 60 degrees with the use of a,graduated pin-sleeve....
Hand surgery basic instrument set...
Hand surgery basic instrument set with round handled instruments...
Medicine Products: