Navigation Links
Nervous Systems of Insects may Offer Clues on Neurodegenerative Diseases

, the proteins will be destroyed in the liver or recognized as foreign by the immune system.

When we started, the objective was to look at the genomes of insects, which just started being sequenced, and figure out what glycosylation enzymes they had and what enzymes they were missing so that we could either add on or subtract an enzyme to duplicate the human pathway, she said.

Palter was intrigued by a paper from Jurgen Roth and his colleagues published in 1992, which reported detecting the complex sugars typical of human proteins in insects, but found they were restricted to the cells of the central nervous system.

Unfortunately, researchers did not believe or follow up on Roths initial study, she said. However, I became interested in what the role of complex glycosylation might be in the central nervous system. As a geneticist, I thought we could use the sophisticated genetic approaches available in the fruit fly to understand this.

This led to a second research project, which involves studying mutant flies that lack the ability to add the terminal sugar, sialic acid, to specific proteins of the central nervous system. Mutant flies exhibit abnormal mating behavior, have defects in their ability to fly and climb, and as they age they experience neurodegeneration resulting in seizures and paralysis.

The nerves of the mutant flies are defective in electrical signaling, which impairs their ability to communicate with one another and muscle cells, Palter said. Our mutant flies may provide a model system to study a class of human diseases whose symptoms include memory loss, ataxia, epilepsy and neurodegeneration.

Both of these studies are being done in collaboration with scientists at Johns Hopkins University, the University of Iowa and New York University Medical School, and have been funded through support from the National Institutes of Health. The researchers have published some of t
'"/>




Page: 1 2 3

Related medicine news :

1. Nervous disorder being treated
2. Anxious Fathers Make Mothers Nervous
3. Nervous System Plays Role In Stem Cell Regulation
4. Sedatives Derived From Chemicals Can Make Elderly Nervous
5. Link Between Immune System And Nervous System
6. Type 1 Diabetes Linked to Stimuli from Nervous System
7. Nervousness Makes Lily Allen Drink!
8. Painkilling Patch As Effective As Intravenous Delivery Systems
9. LINK Applied Genomics Programme Promises To Revolutionize Healthcare Systems
10. New Computerized Imaging Systems Help In Better Dental Treatment Planning
11. Ventilation Systems Not Effective in Blocking Tobacco Smoke
Post Your Comments:
(Date:5/27/2015)... NY (PRWEB) May 27, 2015 Difass ... launched in the U.S. with its first three flagship ... available for purchase nationwide through http://www.difassusa.com . ... person’s health and productivity, but some people struggle with ... night. Dormiva™ is a sleep aid designed to help ...
(Date:5/27/2015)... May 27, 2015 Cincinnati Veterans Affairs Women’s ... for Veterans (CERV) Foundation is proud to host the first ... women Veterans June 11 at the Freedom Center from 6 ... will be the emcee. , This event honors and ... the nation. The banquet is free to the first ...
(Date:5/27/2015)... With InnerVoice Communication App you will be ... not only heard but seen -- by a photograph of ... This award-winning and affordable app takes full advantage of all ... InnerVoice Sender app in conjunction with InnerVoice Communication App, ... for no additional cost. , InnerVoice Sender allows ...
(Date:5/27/2015)... SmarterSkin, http://www.smarterskindermatology.com , is taking skin care customization to ... easier for patients to find skin care products that work ... is a cosmetic dermatologist based in New York and is ... revolutionary DNA test uses 16 genetic markers to evaluate the ... 1. Firmness and elasticity , 2. Glycation , 3. Sun ...
(Date:5/27/2015)... Splashtop Inc., the worldwide leader in cross-device computing ... and extended display product line -- the Mirroring360 ... family room, users can instantly stream their Windows PC or ... an Apple TV, a computer, or a range of media ... or the Google Nexus Player. , The Mirroring360 ...
Breaking Medicine News(10 mins):Health News:Supplement Brand Difass USA Launches in the U.S. with Three Flagship Products Designed to Bring Balance Back to Your Life 2Health News:Cincinnati VA Women’s Health Clinic Celebrates Women Veterans at Awards Banquet 2Health News:Newly Released: InnerVoice Sender App Ups the Ante in Communication Technology for Autism with Remote Prompting 2Health News:Newly Released: InnerVoice Sender App Ups the Ante in Communication Technology for Autism with Remote Prompting 3Health News:Newly Released: InnerVoice Sender App Ups the Ante in Communication Technology for Autism with Remote Prompting 4Health News:SmarterSkin Dermatology is Now Offering Skin DNA Analysis 2Health News:Splashtop Launches the Fastest Computer Screen Mirroring and Extended Display Solution – to Apple TV and other Smart Displays 2Health News:Splashtop Launches the Fastest Computer Screen Mirroring and Extended Display Solution – to Apple TV and other Smart Displays 3
... board of directors of Abbott today declared a quarterly common dividend of ... consecutive quarterly dividend to be paid by Abbott since 1924. The ... the close of business on July 15, 2009. , , Abbott ... 11 percent increase earlier this year - and was again named to ...
... for summer months; 10% of all sales to be donated ... Baking Company (Nasdaq: TSTY ), makers of the ... Lemonade Stand Foundation (ALSF), by announcing the return of Alex,s ... nation,s leading organizations in the fight against childhood cancer, ALSF ...
... June 2009: 92.8% of patients with systemic lupus erythematosus ... their physical and emotional quality of life (QoL), according ... at EULAR 2009, the Annual Congress of the European ... revealed that depression was the most significant factor shown ...
... to anticipate human needs , FRIDAY, June 12 ... a robot that anticipates a human,s needs. , ... Commission,s Joint-Action Science and Technology project, were programmed to ... the robot knows the toy-building process, it observes the ...
... , WOODCLIFF LAKE, N.J., June 12 Par Pharmaceutical Companies, ... P. Rice has been elected to the company,s board of ... Committee and the Nominating-Corporate Governance Committee. , ... Columbia Investments LLC, Baltimore, Maryland, which invests in local businesses ...
... 12 Genaera Corporation ("the Company") (Nasdaq: GENR ... to dissolve the Company. At a Special Meeting of ... a Plan of Complete Liquidation and Dissolution of the Company ... of Dissolution, the Company,s Board of Directors approved the transfer ...
Cached Medicine News:Health News:Tasty Baking Company Supports the Fight Against Childhood Cancer Through Partnership with Alex's Lemonade Stand Foundation 2Health News:Tasty Baking Company Supports the Fight Against Childhood Cancer Through Partnership with Alex's Lemonade Stand Foundation 3Health News:Anxiety and depression lower quality of life in majority of systemic lupus erythematosus patients 2Health News:A Robot That Reads Your Mind? 2Health News:Genaera Corporation Board of Directors Dissolves Corporation and Forms Liquidating Trust 2Health News:Genaera Corporation Board of Directors Dissolves Corporation and Forms Liquidating Trust 3Health News:Genaera Corporation Board of Directors Dissolves Corporation and Forms Liquidating Trust 4
(Date:5/27/2015)... , May 27, 2015  Foundation Health Care  (FDNH), ... related ancillary services, announced today it will present at ... 1-3, 2015 at Luxe Sunset Boulevard Hotel, ... on Tuesday, June 2 nd at 3:00pm and ... a one-on-one meeting please contact LD Micro. For more ...
(Date:5/27/2015)... Calif. , May 27, 2015  Abaxis, Inc. ... point-of-care blood analysis systems, announced today that Ross ... relations, transitioning into the role of chief financial officer ... 2015 Global Healthcare Conference on Thursday, June 4, 2015 ... at the Grand Hyatt in New York ...
(Date:5/27/2015)... 2015  IGI Laboratories, Inc. (NYSE MKT: IG), a ... company, today updated its full year 2015 financial guidance ... Year 2015 Updated Financial Guidance , Total ... are still expected to be between $7.0 and $8.0 ... total revenue for the remainder of the year, and ...
Breaking Medicine Technology:IGI Laboratories Updates Business Outlook 2IGI Laboratories Updates Business Outlook 3
... 11 Professional Products, Inc. (PPI), a leader and ... announced its innovative new Pneumatic Knee Splint (PKS Cryo(TM)). ... anti-migration wrap, the PKS Cryo ( www.PKSCryo.com ... treating post-operative repairs, ligament and soft tissue injuries. , ...
... Solos Endoscopy, Inc. (Pink Sheets: SNDY) is pleased ... MammoView(TM), was featured in the "Product Spotlights" section of ... The article focused on the functionality and its ability ... no discomfort. , The MammoView(TM) instrument line ...
Cached Medicine Technology:Knee Splint's Multi-Compartment Technology Speeds Rehabilitation from Injuries 2Solos Endoscopy, Inc.'s Breast Endoscopy System Featured in November Issue of Healthcare Purchasing News Magazine 2
One step Immunochromatographic Assay for the detection of Respiratory Syncytial Virus...
Rapid Immunoassay for the detection of Respiratory Syncytial Virus....
Rapid, visual assay for the presumptive qualitative detection of Respiratory Syncytial Virus (RSV) directly from nasopharyngeal specimens in neonatel and pediatric patients....
... The BD Directigen EZ RSV Test utilizes ... reagent and one device for rapid RSV detection. ... a method whereby dried reagents have already ... reduced to a two-step process, with clear-cut results ...
Medicine Products: