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Need More And Better Drugs To Tackle Stoke

to the brain rest are due to the leakage of the blood from the arteries thereby increasing the internal pressure of the brain. This is very dangerous as it can squeeze the brain inside the skull.

Symptoms such as numbness or weakness on one side, difficulty in speaking or understanding speech, trouble seeing with one or both eyes, difficulty in walking, feeling of dizziness and severe headache with no reason are the warning symptoms of stroke. The American Heart Association, its subsidiary the American Stroke Association, and the National Stroke Association are educating the public about the seriousness and how lives can be saved if they are given proper treatment at the right time.

The main disadvantage of the drug activase is that it is effective only when it is administered immediately within three hours of the stroke. A small number of patients (40 out of 600) are treated at the Northwestern Memorial Hospital with activase due to their late arrival, after the three-hour window closes say Alberts.

In case of a small group, 4-6% of stoke patients suffer from fatal hemorrhage after the treatment with the activase drug. But when the dug is properly administered it brings back normalcy in case of the stroke patient. Research is going on to find new drugs that work beyond the three-hour window period.

The various drugs that are in the pipeline are Desmoteplase, anti clotting substance that is being tested whether it can be used after the three-hour window period. Factor VII a clotting agent exclusively to treat hemorrhagic stroke. Cerovive an anti-inflammatory drug to prevent the killing of the nerve cells after a stroke.

Activase coupled with ultrasound is also very effective at dissolving clots. Magnetic resonance images (MRIs) can also be used to identify those patients who can be brought back to normalcy after the three-hour window period. Also the new Merci Retrieval System, a corkscrew-like device approved by
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