Navigation Links
Nasal Spray Could Take Drugs Directly to Brain

Delivering drugs via nasal spray might overcome a major obstacle to treating brain ailments such as strokes according to researchers.Based on early studies in rats, researchers from the Stroke Lab and Alzheimer's Research Center in St. Paul, Minnesota, reported that “a direct path from the nose to the brain” could breach the blood-brain barrier, which protects the brain from foreign substances, including drugs.

Senior investigator Dr. William H. Frey II said that his team used a nasal spray to deliver insulin-like growth factor-1, a natural substance that has been shown to protect rat brains from stroke, to tissue deep inside rat brains.// They presented their findings at the American Stroke Association's 26th International Stroke Conference here.In an interview, Frey said this finding is significant because researchers think this same substance may protect human brains from the devastating effects of stroke, but no one has been able to figure out a way to deliver the drug.

“It stops at the blood-brain barrier,” Frey said. “The only way to get it to the brain would be by drilling a hole in the skull and putting the drug in that way. Not a very practical approach.” The nasal spray allows the drug to travel to the brain along “neural pathways directly to the brain,” he said. For example, the olfactory system--the sense of smell--has nerve endings “that reach down to the nose.” The drug travels along those pathways directly to the brain, he said. This method, according to Frey, means the drug reaches the brain much faster than it would if it were administered into a vein.

In this study, Frey and colleagues administered the growth factor to 37 male rats in which the researchers induced brain damage that mimics strokes in human brains. They then tested various motor and sensory reflexes to determine if the rats' symptoms were decreased, indicating that the drug had reached its target.The test results indicated that the drug had “been successfully diffused in brain tissue,” Frey said.

Asked about the implications of Frey's work, Dr. Philip Gorelick, director of the Center for Stroke Research, Chicago, Illinois, said the study was very preliminary but said that it was an intriguing notion. Gorelick pointed out that one of the more daunting aspects of brain research is overcoming the blood brain barrier.

'"/>




Related medicine news :

1. Nasal Spray Could Take Drugs Direct to Brain.
2. Nasal Spray Beats Antihistamine
3. Nasal sprays used for other ailments!
4. Chronic Sinusitis May Be Related To Nasal Mucus
5. Stress – Buster : Hormonal Nasal Spra
6. Cluster Headaches Can Be Treated By Nasal Spray
7. Nasal Plastic Surgery Improves Airway Function
8. Compellis Pharmaceuticals Gets Patent for Obesity-Fighting Nasal Spray CP404
9. Patients Dissatisfied Following Closed Reduction Of Nasal Fractures
10. Nasal Spray Could Take Drugs Direct to Brain.
11. Nasal Spray Beats Antihistamine
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/24/2020)... ... January 24, 2020 , ... Devcool Inc ( http://www.devcool.com ... has completed its spin-off of HiPaaS, Inc ( http://www.hipaas.com ). HiPaaS Inc ... continues its growth and focuses on Healthcare consulting services. , With HiPaaS, ...
(Date:1/23/2020)... ... January 23, 2020 , ... ... scientific training, biomedical research, and patient care—today announced the recipients of the first-of-its-kind ... Equity in Science and Medicine. The awards aim to mitigate gender gaps in ...
(Date:1/23/2020)... ... January 23, 2020 , ... ... LLC, a first-of-its-kind, full-service pulmonology clinic based in Tulsa, to provide patients with ... MCNDOH patients will also have access to HGE Health’s digital symptom management platform, ...
(Date:1/23/2020)... ... January 23, 2020 , ... ... pledged to take action to improve diagnostic quality and safety by joining the ... most prominent organizations in healthcare and patient advocacy. , “Diagnostic error is one ...
(Date:1/23/2020)... SANDY SPRINGS, Ga. (PRWEB) , ... January 23, 2020 , ... ... Dr. Robyn McCalla to become a new member of their professional dental staff. ... of services, including general dentistry, cosmetic dentistry, emergency dentistry and restorative dentistry, ...
Breaking Medicine News(10 mins):
(Date:1/28/2020)... ... January 28, 2020 , ... ... for Maternal-Fetal Medicine’s (SMFM) Pregnancy Meeting in Grapevine, Texas from February 5th ... benefits of a high-performance HD teleultrasound solution. RMTConnectTM allows users to ...
(Date:1/28/2020)... ... , ... According to the American Transplant Foundation, there are 114,000 people in ... surgery this year. Unfortunately, 20 people will die each day as their time passes ... from a lack of available donated organs, but mainly from cumbersome and complex transportation ...
(Date:1/28/2020)... ... January 28, 2020 , ... Knowing it can be difficult ... healthy changes, Isagenix International has launched several offerings, including Snack Bites, ... health and wellness company has also expanded its BEA™ Sparkling Energy Drink and ...
Breaking Medicine Technology: