Navigation Links
Nasal Spray Could Take Drugs Directly to Brain

Delivering drugs via nasal spray might overcome a major obstacle to treating brain ailments such as strokes according to researchers.Based on early studies in rats, researchers from the Stroke Lab and Alzheimer's Research Center in St. Paul, Minnesota, reported that “a direct path from the nose to the brain” could breach the blood-brain barrier, which protects the brain from foreign substances, including drugs.

Senior investigator Dr. William H. Frey II said that his team used a nasal spray to deliver insulin-like growth factor-1, a natural substance that has been shown to protect rat brains from stroke, to tissue deep inside rat brains.// They presented their findings at the American Stroke Association's 26th International Stroke Conference here.In an interview, Frey said this finding is significant because researchers think this same substance may protect human brains from the devastating effects of stroke, but no one has been able to figure out a way to deliver the drug.

“It stops at the blood-brain barrier,” Frey said. “The only way to get it to the brain would be by drilling a hole in the skull and putting the drug in that way. Not a very practical approach.” The nasal spray allows the drug to travel to the brain along “neural pathways directly to the brain,” he said. For example, the olfactory system--the sense of smell--has nerve endings “that reach down to the nose.” The drug travels along those pathways directly to the brain, he said. This method, according to Frey, means the drug reaches the brain much faster than it would if it were administered into a vein.

In this study, Frey and colleagues administered the growth factor to 37 male rats in which the researchers induced brain damage that mimics strokes in human brains. They then tested various motor and sensory reflexes to determine if the rats' symptoms were decreased, indicating that the drug had reached its target.The test results indicated that the drug had “been successfully diffused in brain tissue,” Frey said.

Asked about the implications of Frey's work, Dr. Philip Gorelick, director of the Center for Stroke Research, Chicago, Illinois, said the study was very preliminary but said that it was an intriguing notion. Gorelick pointed out that one of the more daunting aspects of brain research is overcoming the blood brain barrier.

'"/>




Related medicine news :

1. Nasal Spray Could Take Drugs Direct to Brain.
2. Nasal Spray Beats Antihistamine
3. Nasal sprays used for other ailments!
4. Chronic Sinusitis May Be Related To Nasal Mucus
5. Stress – Buster : Hormonal Nasal Spra
6. Cluster Headaches Can Be Treated By Nasal Spray
7. Nasal Plastic Surgery Improves Airway Function
8. Compellis Pharmaceuticals Gets Patent for Obesity-Fighting Nasal Spray CP404
9. Patients Dissatisfied Following Closed Reduction Of Nasal Fractures
10. Nasal Spray Could Take Drugs Direct to Brain.
11. Nasal Spray Beats Antihistamine
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/12/2018)... (PRWEB) , ... September 13, 2018 , ... Glori Blends ... among the industry leaders. , The expo will include vendors, presentations, panel discussions and ... available to educate attendees on their award winning products and assist customers with the ...
(Date:9/3/2018)... (PRWEB) , ... September 03, 2018 , ... Trees with ... hardwoods should be in full leaf and green through September. When a tree is ... winter before other trees of the same type. Giroud Tree and Lawn ...
(Date:9/1/2018)... ... August 31, 2018 , ... Alice Branton shared her ... research health issues with Daytime host Jerry Penacoli. , With all the medical ... Vitamin D deficiency is a major public health problem worldwide irrespective of age, location, ...
(Date:8/31/2018)... ... ... The social impact documentary feature film on homelessness, OFF THE STREETS FOR ... Luciana Lagana, aka Dr. Luciana, has been faring well at film festivals in 2018. ... Film Awards, Shawna Shea Memorial Film Festival, and Top Indie Film Awards. It also ...
(Date:8/31/2018)... ... ... Saturday, September 1st, 2018, Team Fastrax™ will perform their fan favorite patriotic American ... 7pm, the Cyclones will kick off against the South Dakota State Jackrabbits. Just before ... in with their majestic 2,000 sq. ft. American Flag, red white and blue streamers, ...
Breaking Medicine News(10 mins):
(Date:9/1/2018)... ... September 01, 2018 , ... Two Frogs Healing Center, a natural ... hosting the Getting Rid of Lyme Disease Issues with Liposomes Evening Lecture on Wednesday ... , Lyme Disease is the number one vector borne illness in the US and ...
(Date:9/1/2018)... ... September 01, 2018 , ... The 2017 sustainability report released ... continued efforts to “Create a Better Future” through a focus on safe, sustainable ... , “2017 was a positive year for Shaw, as we continued to ...
(Date:8/31/2018)... (PRWEB) , ... August 31, 2018 , ... ... the Government to acquire, such as medications for cancer, mental health and required ... is used to treat Respiratory Distress Syndroms (RDS) in premature babies and can ...
Breaking Medicine Technology: