Navigation Links
Nanoparticle in the Treatment of Glaucoma

Glaucoma is an eye disease that can cause blindness and affects millions of people worldwide. The nanoparticle can safely get past the blood-brain barrier making it an effective non-toxic tool for drug delivery, said Sudipta Seal, an engineering professor with appointments in UCFs Advanced Materials Processing and Analysis Center and the Nanoscience Technology Center.

Seal and his colleagues from North Dakota State University note in the article that while barely 1-3 percent of existing glaucoma medicines penetrate into the eye, earlier experiments with nanoparticles have shown not only high penetration rates but also little patient discomfort. The miniscule size of the nanoparticles makes them less abrasive than some of the complex polymers now used in most eye drops.

Seal and his team created a specialized cerium oxide nanoparticle and bound it with a compound that has been shown to block the activity of an enzyme (hCAII) believed to play a central role in causing glaucoma.

The disease involves abnormally high pressure of the fluid inside the eye, which, if left untreated, can result in damage to the optic nerve and vision loss. High pressure occurs, in part, because of a buildup of carbon dioxide inside the eye, and the compound blocks the enzyme that produces carbon dioxide.

Seal and a team of collaborators including Sanku Mallik, of North Dakota State University, developed the research on using nanoparticles as a delivery mechanism for the compound after supervising a student summer project at UCF. Duke University undergraduate Serge Reshetnikov spent a summer studying nanoscience on UCFs Orlando campus as part of a Research Experience for Undergraduates (REU) project funded by the National Science Foundation. Reshetnikov started looking into the possibilities of using nanoparticles as drug delivery tools. Subsequent research with his advisors led to the specific application for glaucoma.

In their paper on
'"/>




Page: 1 2

Related medicine news :

1. Gene-Nanoparticle Gene Transfer Is Better Than Viral Vector Transfer System
2. Gold Nanoparticles: Agents For Noninvasive Cancer Therapy
3. Alzheimers Can Be Slowed Down By Gold Nanoparticles
4. Gold Nanoparticles Are Good Detectors Biological Toxins
5. Scientists To Study Effect Of Nanoparticles On Liver
6. Nanoparticles and Their Damage to Liver Cells
7. Effect of Nanoparticles on Liver
8. Use of Nanoparticles in Sunscreen under Scrutiny
9. Tiny Sphere Of Nanoparticles Can Fight Cancer
10. Hybrid Nanoparticles for Multimodal Medical Imaging
11. Nanoparticles Used by Researchers to Attack Brain Tumours
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Nanoparticle the Treatment Glaucoma

(Date:12/25/2014)... Thompson HealthDay Reporter WEDNESDAY, ... in on a "fountain of youth" drug that can delay ... adults, a new study suggests. Seniors received a significant ... targets a genetic signaling pathway linked to aging and immune ... The experimental medication, a version of the drug rapamycin, ...
(Date:12/25/2014)... 25, 2014 Thousands of transvaginal mesh ... in a number of multidistrict litigations currently underway in ... Liebhard LLP reports. According to an Order issued on ... a Joint Status Conference in all of the proceedings ... been directed to submit a proposed agenda to the ...
(Date:12/25/2014)... California (PRWEB) December 25, 2014 Plugin ... of ProFire 5k. A fully customizable business presentation tool ... , “Adding the ProFire 5k business tool, users can ... Christina Austin, CEO of Pixel Film Studios. “ProFire 5k ... and style to add professionalism to a presentation” , ...
(Date:12/25/2014)... December 25, 2014 Each year trauma ... 2 million hospital admissions across the nation (according to ... The CDC’s National Hospital Ambulatory Medical Care Survey ... survey conducted in 2010. They estimated that there were ... resulted in a primary diagnosis of broken bone or ...
(Date:12/24/2014)... AlignLife of Wauwatosa loves helping ... items. During the holiday season, AlignLife looks forward to their ... says Dr. Sara Mahalko-Leonhardt, owner of AlignLife. "It brings our ... that we are able to give kids toys for Christmas ... for the generosity of our patients." , The 70 toys ...
Breaking Medicine News(10 mins):Health News:Researchers Take 'First Baby Step' Toward Anti-Aging Drug 2Health News:Researchers Take 'First Baby Step' Toward Anti-Aging Drug 3Health News:Federal Court Overseeing Thousands of Transvaginal Mesh Lawsuits Set to Convene Joint Status Conference for All Litigations, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing Thousands of Transvaginal Mesh Lawsuits Set to Convene Joint Status Conference for All Litigations, Bernstein Liebhard LLP Reports 3Health News:Federal Court Overseeing Thousands of Transvaginal Mesh Lawsuits Set to Convene Joint Status Conference for All Litigations, Bernstein Liebhard LLP Reports 4Health News:Announcing a new ProFire 5k plugin from Pixel Film Studios for Final Cut Pro X Professionals 2Health News:Every Year Four Million Emergency Department Visits Result from Accidents Involving Bone Trauma 2Health News:Every Year Four Million Emergency Department Visits Result from Accidents Involving Bone Trauma 3Health News:Every Year Four Million Emergency Department Visits Result from Accidents Involving Bone Trauma 4Health News:AlignLife of Wauwatosa Brings Joy to Less Fortunate Families 2
... Newer Single-Pill Fixed Combination Brands, According to a New ... , NASHVILLE, Tenn., Dec. 10 HealthLeaders-InterStudy, ... that although Novartis, Exforge and Tekturna have slowly penetrated ... over the last 12 months, their progress has stalled. ...
... Finding Dr. Right brings together in one resource the necessary information to ... time of year , ... Lyndhurst, NJ (PRWEB) December 10, 2008 -- ... figuring out what an otolaryngologist is), navigating the medical landscape can be ...
... Mobile System to Launch in Three Skilled Nursing Facilities ... Dec. 10 After an intense 18-month selection process, ... contract to deploy electronic medical records (EMR) throughout Metropolitan ... , Metropolitan, a nationally ...
... Inc., the world,s leading manufacturer and distributor of automated blood ... Consulting, an expert in Internet software development, team-up to launch ... ... Burtonsville, MD (PRWEB) December 10, 2008 -- ...
... Phase II Cancer Trials and the Company,s Other Clinical Programs All ... - Significant Validation Achieved for Bavituximab and Peregrine,s Anti-PS Anti-Viral ... - Company Enters into Loan Agreement for Up to ... TUSTIN, Calif., Dec. 10 Peregrine Pharmaceuticals, Inc. (Nasdaq: ...
... Dec. 10 Michael Merzenich, PhD, a leading ... the Chief Scientist of Posit Science Corporation, gave ... of a joint conference of the Netherlands Institute ... Arts and Science in Amsterdam. His talk, ...
Cached Medicine News:Health News:Downgraded Tier Positions and Step Therapy Restrictions Have Stalled Exforge's and Tekturna's Growth in The Hypertension Drug Market 2Health News:Downgraded Tier Positions and Step Therapy Restrictions Have Stalled Exforge's and Tekturna's Growth in The Hypertension Drug Market 3Health News:Vitals Launches Free eBook to Help Consumers Find "Dr. Right" 2Health News:Metropolitan Jewish Health System Awards Electronic Medical Records Contract to SigmaCare(R) 2Health News:Metropolitan Jewish Health System Awards Electronic Medical Records Contract to SigmaCare(R) 3Health News:Lifeclinic International and Get Real Consulting Team-Up to Launch Microsoft's HealthVault 2Health News:Peregrine Pharmaceuticals Reports Financial Results for the Second Quarter of Fiscal Year 2009 2Health News:Peregrine Pharmaceuticals Reports Financial Results for the Second Quarter of Fiscal Year 2009 3Health News:Peregrine Pharmaceuticals Reports Financial Results for the Second Quarter of Fiscal Year 2009 4Health News:Peregrine Pharmaceuticals Reports Financial Results for the Second Quarter of Fiscal Year 2009 5Health News:Peregrine Pharmaceuticals Reports Financial Results for the Second Quarter of Fiscal Year 2009 6Health News:Peregrine Pharmaceuticals Reports Financial Results for the Second Quarter of Fiscal Year 2009 7Health News:Peregrine Pharmaceuticals Reports Financial Results for the Second Quarter of Fiscal Year 2009 8Health News:Peregrine Pharmaceuticals Reports Financial Results for the Second Quarter of Fiscal Year 2009 9Health News:Peregrine Pharmaceuticals Reports Financial Results for the Second Quarter of Fiscal Year 2009 10Health News:Peregrine Pharmaceuticals Reports Financial Results for the Second Quarter of Fiscal Year 2009 11Health News:Posit Science Co-Founder and Brain Plasticity Pioneer, Michael Merzenich, Speaks at Science Conference in the Netherlands 2
(Date:12/22/2014)... JUNCTION, N.J. , Dec. 22, 2014 /PRNewswire/ ... company marketing its CytoSorb® blood purification technology to ... surgery patients in 28 countries worldwide, today announced ... Russo , MD, FACS, as its Senior Vice ... Dr. Di Russo ...
(Date:12/22/2014)... DUBLIN , Dec. 22, 2014 Research and ... addition of the "US Self-monitoring Blood Glucose Market" ... http://photos.prnewswire.com/prnh/20130307/600769 This market insight focuses ... in the United States . Reimbursement ... studied. Thorough product analyses for more than 73 SMBG ...
(Date:12/22/2014)... a privately-held medical products and technologies company, today announced ... Officer of the company, effective December 22, 2014. ... Board of Directors of ConvaTec thanks Mr. Berger for ... years," said Magnus Lundberg , the Chairman of ... company is well positioned for the future."  The company ...
Breaking Medicine Technology:CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 2CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 3CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 4CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 5US Self-monitoring Blood Glucose Market 2ConvaTec Names Paul Moraviec Interim CEO Effective December 22, 2014 2
... , May 25 Informed Medical ... medical forums and integrated medical communications for the ... initiative, responding to the FDA,s new program to ... level of complexity the FDA,s "Bad Ad Program" ...
... , May 25 Stryker’s Communications business unit and ... integrate both companies’ technologies within the operating room to provide customers ... solutions. , , ... Stryker’s Infinity Control System allows staff within the OR to route ...
Cached Medicine Technology:Informed Medical Communications Takes the Lead in Response to FDA's 'Bad Ad Program' 2Stryker Enters Strategic Marketing Agreement with Acuitec 2Stryker Enters Strategic Marketing Agreement with Acuitec 3
... Stand Magnifier offers versatility across a ... lens and the light are adjustable. ... hand held objects can be worked ... parallel to the work surface, lay ...
Bausch & Lomb magnifiers incorporates precision optics and patented ergonomic designs for increased clarity and comfort during use....
... Piston assembly fits into neck of platform ... ready position after use. Cutting block fits ... disposable trephine blades sized 6.25 - 9.0 ... the preparation of corneal donor buttons for ...
... allows the surgeon to effectively ... scrub-resistant, gentian violet ink. All ... sterile, with a ruler and ... pouches. Micro tip marker for ...
Medicine Products: