Navigation Links
Nanoparticle Research Offers Hope of Artificial Retinas, Prostheses

Researchers have achieved the world’s first direct electrical link between nerve cells and photovoltaic nanoparticle films. The development opens the door to// applying the unique properties of nanoparticles to the possible development of a nanoparticle-based artificial retina.

Nanoparticles are artificially created bits of matter not much bigger than individual atoms. The same forces that shape molecules control their behavior; they also exhibit the bizarre effects associated with quantum mechanics. Scientists can exploit these characteristics to custom-build new materials "from the bottom up" with characteristics such as compatibility with living cells and the ability to turn light into tiny electrical currents that can produce responses in nerves.

That's what the UTMB and Michigan researchers did, using a process devised by Michigan chemical engineering professor Nicholas Kotov, one of the authors of a paper on the research appearing in the current issue of Nano Letters. The process starts with a glass plate and then builds a layer-by-layer sandwich of two kinds of ultra-thin films, one made of mercury-tellurium nanoparticles and another of a positively charged polymer called PDDA. The scientists then added a layer of ordinary clay and a cell-friendly coating of amino acid, and placed cultured neurons on the very top.

When light shines on them, the mercury-tellurium nanoparticle film layers produce electrons, which then move up into the PDDA film layers and produce an upward-moving electrical current. "As you build up the layers of this, you get better capabilities to absorb photons and generate voltage," said UTMB research scientist Todd Pappas, lead author on the Nano Letters paper. "When the current reaches the neuron membrane, it depolarizes the cell to the point where it fires, and you get a signal in the nerve."

Although light signals have previously been transmitted to nerve cells using silicon (whose abilit y to turn light into electricity is employed in solar cells and in the imaging sensors of video cameras), nanoengineered materials promise far greater efficiency and versatility.

"It should be possible for us to tune the electrical characteristics of these nanoparticle films to get properties like color sensitivity and differential stimulation, the sort of things you want if you're trying to make an artificial retina, which is one of the ultimate goals of this project," Pappas said. "You can't do that with silicon. Plus, silicon is a bulk material -- silicon devices are much less size-compatible with cells."

The researchers caution that despite the great potential of a light-sensitive nanoparticle-neuron interface, creating an actual implantable artificial retina is a long-range project. But they're equally hopeful about a variety of other, less complex applications made possible by a tiny, versatile light-activated interface with nerve cells -- such things as new ways to connect with artificial limbs and other prostheses, and revolutionary new tools for imaging, diagnosis and therapy.

Source-Bio-Bio Technology
'"/>




Related medicine news :

1. Gene-Nanoparticle Gene Transfer Is Better Than Viral Vector Transfer System
2. Gold Nanoparticles: Agents For Noninvasive Cancer Therapy
3. Alzheimers Can Be Slowed Down By Gold Nanoparticles
4. Gold Nanoparticles Are Good Detectors Biological Toxins
5. Scientists To Study Effect Of Nanoparticles On Liver
6. Nanoparticles and Their Damage to Liver Cells
7. Effect of Nanoparticles on Liver
8. Use of Nanoparticles in Sunscreen under Scrutiny
9. Tiny Sphere Of Nanoparticles Can Fight Cancer
10. Hybrid Nanoparticles for Multimodal Medical Imaging
11. Nanoparticles Used by Researchers to Attack Brain Tumours
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... 2017 , ... Lori R. Somekh, founder of the Law Office of ... elder law and special needs planning attorneys. “Membership in ElderCounsel helps our office remain ... to network with elder law attorneys nationwide,” said Somekh. , ElderCounsel ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Many families ... However, many long-term care insurance companies have a waiver for care if the client ... elimination period, when the family pays for care, is often waived, so the benefits ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading ... to advocate for action towards gender equality at their inaugural Summit in New York ... globe, and reached a social audience of over 3 million. To watch the Mobilize ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House ... most popular and least understood books in the Holy Scriptures, Revelation. The Book of ... baffled scholars for centuries. Many have tossed it off as mere rubbish, but Yisrayl ...
(Date:10/13/2017)... VA (PRWEB) , ... October 13, 2017 , ... ... of DevOps and Agile Software Development, has been awarded a contract by the ... Blanket Purchase Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies ...
Breaking Medicine News(10 mins):
(Date:9/23/2017)... , Sept. 22, 2017 Janssen Biotech, Inc. ... response letter from the U.S. Food and Drug Administration ... of sirukumab for the treatment of moderately to severely ... additional clinical data are needed to further evaluate the ... severely active RA. ...
(Date:9/22/2017)... , Sept. 22, 2017 AVACEN Medical (AVACEN) ... is now successfully helping those with the widespread pain ... Fibromyalgia diagnosed Amanda in Essex, England ... washing my hair, experiencing no sleep at all, tremendous ... spasm… I cannot recommend [the AVACEN 100] enough, how ...
(Date:9/19/2017)... , Sept. 19, 2017   ZirMed Inc ., a ... today announced that it has been ranked #1 by its ... Book™ Rankings 2017 User Survey. ZirMed was recognized as ... large hospitals and medical centers over 200 beds and holds ... healthcare technology user survey history. ...
Breaking Medicine Technology: