Navigation Links
NIH Awards Emory $3.6 Million for Schizophrenia Gene Research

The National Institute of Mental Health of the National Institutes of Health has awarded Emory University School of Medicine a $3.6 million research grant to test schizophrenic patients for a recently discovered variation in the human genome. The project is led by Stephen T. Warren, PhD, Timmie Professor and chair of the Department of Human Genetics.

Schizophrenia is a severe and common psychiatric disorder that has a strong genetic predisposition. Despite the knowledge that genetic changes can lead to the disorder, however, few genes have been identified.

Recently, scientists have discovered an entirely new and previously unknown form of variation in the human genome, called "copy number variation," or CNV. This variation includes deletions and duplications of segments of DNA previously unrecognized in the general population.

Scientists now believe every individual may carry as many as 100 CNVs. While these variations generally do not cause disease on their own, says Dr. Warren, in combination with other genetic changes and/or environmental factors they may well contribute to one's overall risk of disease.

Using cutting-edge technology available to only a few major research centers, the Emory project will screen a collection of 500 schizophrenic patients and 500 controls (individuals without schizophrenia) for CNV throughout the entire human genome.

The new technology uses "DNA chips," manufactured by NimbleGen Systems, Inc., that can compare DNA copy number differences in a reference genome to the genomes of the individuals being screened. Scientists can array 2.1 million locations in the genome, or about one in every 1,000 base pairs, on a single chip the size of a microscope slide. The project team will use the new Emory high performance computer cluster to analyze the data.

"By helping us identify CNVs, we believe this new kind of chip technology may lead us to the specific gen es that influence schizophrenia and other major psychiatric diseases," Dr. Warren says.

The schizophrenia project is the first involvement in a disorder other than fragile X syndrome in over a decade for Dr. Warren, who is well know for his discoveries regarding this frequent form of mental retardation.

The Emory scientists are collaborating with Ann E. Pulver, ScD, professor of psychiatry and behavioral sciences at Johns Hopkins University, who collected the samples to be tested.


'"/>




Related medicine news :

1. Aussie Nobel Prize Winners Receive Their Awards
2. Prestigious Gairdner Awards for medical research in 2006 Goes To Two Yale biologists
3. The President Gives Away National Disability Awards
4. Majority of Padma Awards Go to Doctors from Delhi
5. US, Indian Doctors Bag Thai Medical Awards
6. WHO Awards Prequalification Status to the First UAE Approved Vaccine
7. Bio-Rad Gets Life Science Industry Awards – 200
8. Talwalkars Awards a Record $1 Million Order to Nautilus
9. Ontario Court Awards Compensation To Paralyzed Worker
10. Michael J. Fox Foundation Awards $710,000 to Understanding of Parkinsons Disease Subtypes
11. Researchers from Emory University Undertake A New Genetic Mapping
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/23/2017)... , ... June 23, 2017 , ... ... Private Flood Insurance offerings. With the Federal Emergency Management Agency’s (FEMA) recent update ... the United States. In 2012, the Biggert-Waters Act was enacted to reflect the ...
(Date:6/23/2017)... San Francisco, CA (PRWEB) , ... June 23, 2017 , ... ... Conference on 26th June, 2017 from 9 am to 3 pm to present to ... curriculum. The program is an original curriculum project led by The Health Improvement ...
(Date:6/23/2017)... IL (PRWEB) , ... June 23, 2017 , ... ... management assistance and financial planning services to communities in the greater Chicago metropolitan ... Association to offer assistance to underprivileged youth in Chicago. , Founded in 1897, ...
(Date:6/23/2017)... (PRWEB) , ... June 23, 2017 , ... ... services and personal financial planning to families and business owners in North Central ... organization to help provide services to differently abled residents in the region. , ...
(Date:6/22/2017)... ... June 22, 2017 , ... Branches, Inc. has been partnering with The ... funding to support its programs focused on providing opportunity to low-income families and breaking ... by the Foundation of $15,000 to support its , Climb to College & Career ...
Breaking Medicine News(10 mins):
(Date:6/7/2017)... Specialty Infusion Group, a brand of Diplomat Pharmacy, Inc. (NYSE: DPLO), ... location. The Iowa ... 7 cleanroom—the standard needed to compound intravenous (IV) nutrition formulations. A ... "Our new cleanroom will allow ... Iowa patients," said Phil Rielly , ...
(Date:6/1/2017)... Pa. , June 1, 2017 Nutriceutical ... and Veterinarian Recommended Solutions (VRS), and KD Pharma Group ... in Nutriceutical Holdings by KD Pharma Group. KD Pharma ... with the option to acquire the entire company. ... in KD. They are committed to growing the NH ...
(Date:5/26/2017)... DUBLIN , May 26, 2017  Endo International plc ... Campanelli , President and CEO, will represent the Company in ... Global Healthcare Conference on Tuesday, June 13, 2017 at 10:40 ... held at Terranea Resort in Rancho Palos Verdes, ... archive for the event will be available on the Company,s ...
Breaking Medicine Technology: