Navigation Links
Myelin Associated With Early Evolution of Huntington's Disease

A new study has found that a breakdown of myelin is associated with the early evolution of Huntington's disease. Last month, Dr. George Bartzokis, director of the UCLA Memory Disorders and Alzheimer's Disease Clinic, suggested in the journal Alzheimer's and Dementia that the collapse of a type of myelin that develops late in life promotes the enlargement of toxic amyloid plaques long associated with Alzheimer's disease. Myelin is the "insulation" that wraps around nerve axons in the brain.

Now, in a new report presently online in the journal Neurochemical Research, Bartzokis turns his concentration to Huntington's disease. Again, he suggests that a breakdown of myelin is the cause, but with a twist - it is the myelin that develops early in the formation of the brain that breaks down ahead of time and ultimately leads to the disease's symptoms.

Huntington's disease (HD) is an uncommon, inherited neurological disorder that eventually deprives individuals of their ability to be in charge of their movement, behaviour and thinking. It affects around 30,000 people in the U.S., with another 150,000 at risk.

While it is known that HD is caused by a mutation in a gene called Huntingtin (Htt), the correct mechanism by which the Htt gene causes or contributes to neuronal cell death and HD symptoms remains uncertain. Bartzokis' research suggests that it is Htt's influence on myelin that may prove to be the cause.

The earliest parts of the developing brain include systems of neurons that control movement and behaviour. These neurons have long axons, finger-like projections that serve as the main transmission lines of the nervous system, covered with thick myelin sheaths. The sheaths are nourished by an ongoing supply of a protein called brain-derived neurotrophic factor, which travels down a neuron's axon.

Bartzokis believes that the Htt gene gets in the way of this nourishment-delivery system, causing a
'"/>




Page: 1 2 3

Related medicine news :

1. Blame Myelin for Many Neuropsychiatric Disorders
2. Moderate Use of Analgesics - Not Associated With Kidney Dysfunction
3. Bayer Voluntarily Withdraws BAYCOL - A Drug Associated With 50 Deaths
4. Associated therapy for multiple myeloma
5. Associated scan for detecting ovarian cancer spread
6. Ginseng Associated with Pregnancy Risks
7. Enzyme Associated with Memory
8. 3 die, 500 sickened in nations largest hepatitis A outbreak Associated Press
9. Enzyme Associated With Memory
10. Problems Associated With Iron Deficiency
11. Asbestos Exposure Associated With An Increased Risk For Autoimmune Disease
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Myelin Associated With Early Evolution Huntington Disease

(Date:3/6/2015)... Sanjay Gupta, MD, CNN’s Emmy award-winning ... at ATA 2015, the American Telemedicine Association's (ATA) ... world’s largest telemedicine, telehealth and mHealth meeting. , ... for several of CNN’s headlining programs including New ... DuPont Award winning WEED series. He has created ...
(Date:3/6/2015)... Ticket Down is a reputable source for ... the Moda Center. After being away from the touring ... no signs of letting up on his “Garth Brooks World ... wife, Trisha Yearwood, to venues around the United States. The ... acclaimed tour to the Moda Center in Portland, OR. The ...
(Date:3/6/2015)... March 06, 2015 Ticket Down is a ... popular ticket exchange has extended their customer appreciation discount code ... Bridge, West Yorkshire England and he began his career in ... the past couple of years Ed Sheeran has become a ... Sheeran is on stage he is having the time of ...
(Date:3/6/2015)... 2015 At Natural Products Expo ... the launch of its powerful, location-aware iOS app ... sustainable products at any retailer that carries those ... Expo West Booth 6054. , Makeena’s proprietary ... non-GMO, organic, Paleo, and vegan, among many other ...
(Date:3/6/2015)... Many patients with knee osteoarthritis have ... you (or someone you know) have chronic pain and ... be interested in the ACT-OA clinical trial. , ... he is one of fifteen physicians in the U.S. ... subjects as part of a new, multi-site, double blind, ...
Breaking Medicine News(10 mins):Health News:CNN’s Dr. Sanjay Gupta Among Headliners at American Telemedicine Association 2015 Annual Meeting 2Health News:Garth Brooks Tickets in Portland, OR at the Moda Center: Ticket Down Slashes Garth Brooks Ticket Prices at the Moda Center in Portland 2Health News:Garth Brooks Tickets in Portland, OR at the Moda Center: Ticket Down Slashes Garth Brooks Ticket Prices at the Moda Center in Portland 3Health News:Ed Sheeran Tickets in Indianapolis, Austin, Albany, St. Louis, London, Des Moines, Salt Lake City, Saskatoon, Regina and Denver/Morrison Now On Sale at Ticket Down 2Health News:Makeena Launches App that Makes Healthy and Sustainable Products More Affordable for Shoppers 2Health News:Makeena Launches App that Makes Healthy and Sustainable Products More Affordable for Shoppers 3Health News:Kevin Darr, M.D. is Now Enrolling Patients in a New FDA-Approved Clinical Trial Evaluating Adipose-Derived Regenerative Cells in the Treatment of Knee Osteoarthritis 2
... , , WALTHAM, Mass., ... country, often in dangerously hot weather conditions, Mobile Sports, Inc. ... iPhone application giving athletes, parents of athletes, coaches, and athletic ... and other, more serious heat-related illnesses. , ...
... , TEMPLE, Texas, Aug. 31 Scott & ... Texas Department of State Health Services for the next three years. Scott ... 2003. In May of this year, Scott & White Hospital was ... Surgeons Committee on Trauma (ACSCOT), the first step in receiving its official ...
... BEIJING, Aug. 31 /PRNewswire-Asia/ -- ... today that the Company,s,Chinese subsidiary, Beijing Rain and ... Municipal No.3 People,s Hospital ("HangZhou,No.3 Hospital"), entered into ... $4,800,000 RMB (approximately $703,000USD). , ...
... , ... as President of Health Science and Careers Division , ... New York (PRWEB) August 31, 2009 -- The education and technology ... Health Science and Careers division of its Professional & Career business., , , , ,Pearson,s ...
... , PARSIPPANY, N.J., Aug. 31 Endometrin(R) ... (progesterone gel) for progesterone supplementation, according to the results of ... increase endometrial receptivity for implantation of an embryo and to ... ENDOMETRIN(R) rapidly reached higher progesterone serum concentrations, produced greater systemic ...
... , , , , ... white after Labor Day," yet this rule is so passe. Don,t stick to ... a slave to fashion rules and have been spotted in white all year-round, ... wear the shade head-to-toe, you can wear white as you wish with a ...
Cached Medicine News:Health News:New Technology Helps Athletes Prevent Dehydration and Heat-Related Illness 2Health News:Scott & White Memorial Hospital Receives Level I Trauma Center Re-designation Again 2Health News:RainEarth (RNER) Signs Purchase Agreement with HangZhou Municipal No.3 People's Hospital 2Health News:RainEarth (RNER) Signs Purchase Agreement with HangZhou Municipal No.3 People's Hospital 3Health News:Pearson Announces Leah Jewell as President of Health Science and Careers Division 2Health News:Pearson Announces Leah Jewell as President of Health Science and Careers Division 3Health News:Recently Published Study Demonstrates Pharmacokinetic Advantages of ENDOMETRIN(R) Over Crinone(R) for Progesterone Supplementation 2Health News:Recently Published Study Demonstrates Pharmacokinetic Advantages of ENDOMETRIN(R) Over Crinone(R) for Progesterone Supplementation 3Health News:Photos: Breaking The 'No White After Labor Day' Fashion Myth 2
(Date:3/5/2015)... 2015 BioLineRx (NASDAQ: BLRX ... to identifying, in-licensing and developing promising therapeutic candidates, ... public offering of American Depositary Shares ("ADSs"), each ... of the ADSs in the offering are to ... Securities is acting as sole book-running manager for ...
(Date:3/5/2015)... Calif., March 5, 2015  IRIDEX Corporation (Nasdaq: ... and year ended January 3, 2015.  , Revenues ... record for the Company and up 11% from $10.6 million ... million, also a record, up 12% from $38.3 million in ... was 50.1%, up from 48.6% in the fourth quarter of ...
(Date:3/5/2015)... March 5, 2015  BioPhotas, Inc., an FDA registered ... patented photo-therapeutic technologies to treat skin, muscle and joint ... Semper Fi Fund to provide BioPhotas, flagship product, the ... pain management solutions.  Commenting on the ... who used the Celluma at the Warrior Hope and ...
Breaking Medicine Technology:BioLineRx Announces Underwritten Public Offering of its American Depositary Shares 2BioLineRx Announces Underwritten Public Offering of its American Depositary Shares 3IRIDEX Reports 2014 Fourth Quarter, Year-End Results 2IRIDEX Reports 2014 Fourth Quarter, Year-End Results 3IRIDEX Reports 2014 Fourth Quarter, Year-End Results 4IRIDEX Reports 2014 Fourth Quarter, Year-End Results 5IRIDEX Reports 2014 Fourth Quarter, Year-End Results 6IRIDEX Reports 2014 Fourth Quarter, Year-End Results 7IRIDEX Reports 2014 Fourth Quarter, Year-End Results 8BioPhotas, Inc. and the Semper Fi Fund Work Together to Provide Pain Relief to Injured Service Members 2BioPhotas, Inc. and the Semper Fi Fund Work Together to Provide Pain Relief to Injured Service Members 3
... NEW YORK, Sept. 30 Law firm Clifford Chance, as ... its merger with Wyeth under China,s Anti-Monopoly Law. The clearance ... September 2009. , Competition approval from the Chinese authorities was ... , The EU has already approved the deal; decisions ...
... , LAKE FOREST, Ill., Sept. 30 Hospira, Inc. ... medication delivery company, today announced the acquisition of worldwide ... affiliated European manufacturing facility from PLIVA Hrvatska d.o.o. (Zagreb, ... Hospira,s reach and vertical integration in biogenerics. Financial ...
Cached Medicine Technology:Clifford Chance Advises Pfizer on Conditional Clearance in China of Its Merger with Wyeth 2Hospira Acquires Worldwide Rights to Biogeneric Version of Filgrastim and Manufacturing Facility From PLIVA 2Hospira Acquires Worldwide Rights to Biogeneric Version of Filgrastim and Manufacturing Facility From PLIVA 3
Medtronic Ophthalmics offers a comprehensive selection of corneal trephine,blades and handles. Handcrafted, sharp, uniform blade edges promote a,symetrical and vertical cut of all corneal layers....
Medtronic Ophthalmics offers a comprehensive selection of corneal trephine,blades and handles. Handcrafted, sharp, uniform blade edges promote a,symetrical and vertical cut of all corneal layers....
Medtronic Ophthalmics offers a comprehensive selection of corneal trephine,blades and handles. Handcrafted, sharp, uniform blade edges promote a,symetrical and vertical cut of all corneal layers....
Medtronic Ophthalmics offers a comprehensive selection of corneal trephine,blades and handles. Handcrafted, sharp, uniform blade edges promote a,symetrical and vertical cut of all corneal layers....
Medicine Products: