Navigation Links
Mutated Gene Zaps Pancreas Cancer in Mice

A mutated gene named Bik can shrink or kill tumors in the pancreas of mice, US researchers said in a study published Monday, offering hope for one of the deadliest human cancers

The mutant gene named Bik expresses a protein that forces cancer cells to kill themselves, researchers from The University of Texas MD Anderson Cancer Center said.

The team even created a more lethal mutant, called BikDD, which spares healthy tissue.

"There are no good options for pancreatic cancer patients now," said James Abbruzzese, professor and chair of MD Anderson Department of Gastrointestinal Oncology.

Two types of mice were treated after they were infected with two aggressive lines of pancreatic cancer, one in a very advanced stage.

Infected control mice in both groups died within 40 days without treatment, while at least half those who received the aggressive BikDD mutant gene survived for 14 months with no signs of cancer.

"This vehicle, or vector, is so targeted and robust in its cancer-specific expression that it can be used for therapy and perhaps for imaging" that could lead to early cancer detection, said Mien-Chie Hung, professor and chair of Anderson center and senior author of the study.

"This looks like a promising approach to gene therapy for pancreatic cancer and we are working to bring it to a clinical trial," said Abbruzzese.

He estimated it will take between one and two years to complete US Food and Drug Administration requirements for Phase I clinical trial in humans. The side effects in mice were mild, they said, which is rare for cancer treatments.

Pancreatic cancer kills 96 percent of human victims within five years of diagnosis, one of the lowest cancer survival rates.

Some 37,000 cases of pancreatic cancer are diagnosed annually in the United States. Early diagnosis is extremely difficult, so the disease is often discovered
'"/>




Page: 1 2

Related medicine news :

1. Mutated Viruses Can Cure Tumors
2. Gene Responsible For Mammary Gland Function, When Mutated Results in Leukemias
3. Mutated Gene and Bad Habits can Lead to Age-related Macular Degeneration
4. Pancreas transplant gives hope to type 2 diabetes
5. Pancreas Transplant for Diabetics
6. Stomach Bruises Can Lead To Pancreas Infection
7. Once-Diabetic Heart/Kidney/Pancreas Transplant Recipient Enjoys Life (And Eating Again)
8. Fibroids unlikely to Turn Cancerous
9. Virus Level could Predict Cervical Cancer Risk
10. Cancer Doctors Okays Controversial Prostate Therapy
11. Potential New Cancer Gene Identified
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Mutated Gene Zaps Pancreas Cancer Mice

(Date:1/22/2015)... 22, 2015 Liberty University has received accreditation ... program from the Council for Accreditation of Counseling & ... Liberty’s Center for Counseling & Family Studies , is ... the university’s new School of Behavioral Sciences. Prior to the ...
(Date:1/22/2015)... Gabe’s Chemo Duck Program is pleased to announce the release of ... kids with cancer. The Chemo Duck App, available on iTunes for ... games to help children of all ages living with cancer adjust ... kids entertained, educated and at ease while waiting for clinic visits ...
(Date:1/22/2015)... is a famous wedding dress company offering many trendy designs. ... Facebook, Twitter, and Pinterest. The fans will have an opportunity ... every week. , Moreover, the company has extended its 2015 ... homepage for more information. , Angelweddingdress is a ...
(Date:1/22/2015)... Orlando, Florida (PRWEB) January 22, 2015 ... up today at the 2015 PGA Merchandise Show to ... lady and incredible female amateur golfer, Arlene McKitrick. The ... career female amateur golf tournament win. She won her ...
(Date:1/22/2015)... For over 20 years, Dr. David Cruz of ... area has treated just about every type of injury that ... And for those same twenty-plus years, the team at Doctors ... with the best possible doctor. With the combined breadth ...
Breaking Medicine News(10 mins):Health News:Liberty University's Resident Master’s Counseling Program Receives CACREP Accreditation 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 3Health News:Angelweddingdress Invites Its Customers To Follow It On Facebook, Twitter, And Pinterest 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 2Health News:All-Time Leading Female Amateur Golfer Arlene McKitrick Receives Juvent Sports Achievement Award at 2015 PGA Show 3Health News:Industry Leading Chiropractor in Oceanside Joins the Doctors on Liens Network 2
... and Dr. Roseanna Means Recognized with the 2008 CVS ... Caremark Heroes in Women,s Health Award, WOONSOCKET, R.I., ... of women,s health, CVS Caremark has,named Dr. Marianne Legato and Dr. ... Health Award. The honorees were recognized,last evening at an event in ...
... Time Ubell Prize Announced to Recognize Outstanding Journalism in, Support of ... ... Understanding, NEW YORK, May 9 Although the weatherman predicted rain,that ... Central Park on Saturday, April 26th to unite as a passionate and,dedicated ...
... Senior Living,Inc. (NYSE: SRZ ), today announced that ... the 2008 Bank of America Healthcare,Conference in Las Vegas ... Sunrise will Web cast the presentation live on ... ). A,replay of the Web cast will be available ...
... May 9 Claremont Insurance,Services ( http://www.claremontcompanies.com ... today announced an innovative partnership to,market and ... broker,channel. PayrollSelect expands the selling power and ... an additional recurring revenue,stream for the broker ...
... depression before the diagnosis, , , FRIDAY, May 9 (HealthDay ... as likely to develop post-traumatic stress disorder if they ... suggests. , About 16 percent of the 74 breast ... University Medical experienced PTSD 18 months after their cancer ...
... University School of Medicine in St. Louis working with ... cells long thought to be responsible for type 1 ... immune cells from isolated insulin-making structures in the pancreas ... immune cells, known as dendritic cells, "red-handed": carrying insulin ...
Cached Medicine News:Health News:CVS Caremark Honors Heroes in Women's Health 2Health News:CVS Caremark Honors Heroes in Women's Health 3Health News:14th Annual Parkinson's Unity Walk Most Successful Event to Date 2Health News:14th Annual Parkinson's Unity Walk Most Successful Event to Date 3Health News:New Payroll Service Expands Selling Power and Service Capability of Employee Benefits Brokers 2Health News:Mood Disorders Put Breast Cancer Patients at Risk for PTSD 2Health News:Suspected cause of type 1 diabetes caught 'red-handed' for the first time 2Health News:Suspected cause of type 1 diabetes caught 'red-handed' for the first time 3
(Date:1/23/2015)... N.C. , Jan. 23, 2015 For the pharmaceutical ... in dealing with payers. Likewise, the importance of the managed ... will only continue to grow as payer formularies and provider ... therapies. At the same time, managed markets leaders ...
(Date:1/23/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/5dh22x/urinary_catheters ) ... Market (Indwelling or Foley Catheters, Intermittent Catheters and Male ... Share, Growth, Trends and Forecast 2014 - 2020" ... present, the global market for urinary catheters is experiencing ...
(Date:1/23/2015)...  MedScope ( www.medscope.org ), the leading provider of medical ... Connected World magazine Connected World Award for its ... be used anywhere, anytime. The nomination was made by ... nominating MedScope, Landon Garner , Director of Marketing ...
Breaking Medicine Technology:As Payer Influence Rises, Pharmaceutical Companies work to Optimize the Managed Markets Function 2Urinary Catheters Market (Indwelling or Foley Catheters, Intermittent Catheters and Male External or Condom Catheters) - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 2Urinary Catheters Market (Indwelling or Foley Catheters, Intermittent Catheters and Male External or Condom Catheters) - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 3MedScope Nominated by RacoWireless for Prestigious 2015 Connected World Magazine Connected World Award 2
... WEST BEND, Wis., Aug. 8, 2011 Eurofins ... service provider and Spaulding Clinical Research, LLC., US-based, ... Device Manufacturer, announce a joint partnership agreement.  This ... facilitates collaboration on integrated clinical services to engage ...
... Va., Aug. 8, 2011 Science Applications International ... has completed the acquisition of Vitalize Consulting Solutions ... and information technology (IT) services for healthcare enterprises. ... the commercial hospital market that are implementing electronic ...
Cached Medicine Technology:Spaulding Clinical Announces New Joint Partnership for Global Studies with Eurofins Optimed Clinical Research 2SAIC Completes Acquisition of Vitalize Consulting Solutions, Inc. 2
... classic designs paired with modern, feminine styling. ... materials including ultra-light titanium to 3-D acetate ... almonds and squares. Three-piece mounts and nylon ... wear collection is the perfect combination of ...
... The new Chanel optical collection, ... elegance dear to Mademoiselle's heart, ... to the quilted effect. Combining ... the sparkle of Strass and ...
... Luxury and professionalism. Glamour and style. Creativity ... Luxottica, two market-leading companies, signed a new ... Gabbana brand was formed in 1985 by ... Stefano Gabbana, who blended sensuality with their ...
... includes three collections - Nike Suns, Nike ... active lifestyle consumers the latest vision technology ... sun collections feature Nikes Max Lens technology ... larger vision sweet spot for optimal sport ...
Medicine Products: