Navigation Links
Multiple Sclerosis Can Be Treated By Blocking Fat Hormone

The blocking of the leptin hormone which is mostly produced in fats cells has a good effect with regard to multiple sclerosis (MS), according to// Italian researchers. Giuseppe Matarese and colleagues from Università di Napoli "Federico II" suggest that leptin neutralization may be a possible way to both prevent and treat MS.

Leptin is known to play a critical role in the regulation of food intake, metabolism, and the immune response. Since it had been previously shown that leptin is expressed in active inflammatory lesions of the central nervous system during EAE and MS, Matarese and colleagues investigated the effects of leptin blockade on the induction and progression of EAE in mice.

They found that leptin blockade in mice, by the use of either anti-leptin antibodies or a form of the leptin receptor unable to bind leptin, either before or after disease onset improved clinical symptoms of disease, slowed disease progression, reduced disease relapses, and reduced the number of antigen-specific T cells.

The authors delved further to unravel the cellular signaling events underlying these beneficial effects. Taken together, the data provides a basis for the development and testing of novel strategies of leptin-based targeting for the potential treatment of MS.

Edited (ANI)
'"/>




Page: 1

Related medicine news :

1. Naked DNA Vaccination May Conquer Arthritis and Multiple Sclerosis
2. Multiple organ disease cured by genes
3. Adult stem cells in treatment for Multiple sclerosis (MS)
4. Life Quality For Patients With Multiple Sclerosis
5. Effective Pain Relief For Patients Suffering From Multiple Sclerosis
6. The Link Between Hepatitis B Vaccine And Multiple Sclerosis Questioned
7. Hope For Patients With Multiple Sclerosis
8. Individuals Born In May At A Higher Risk Of Developing Multiple Sclerosis
9. Debating The Link Between Sex Hormones And Multiple Sclerosis
10. Warning Issued by FDA on consumption of the drug Tysabri used to treat Multiple Sclerosis
11. Decreasing Multiple Births By Single Embryo Transfers
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/23/2017)... ... 23, 2017 , ... TSC Advantage has been awarded Gold ... Solution Innovations and Security Solution for Government Innovations. Both gold awards recognize TSC ... DHS SAFETY Act-designated enterprise security assessment approach. , The ninth annual Golden Bridge ...
(Date:8/22/2017)... ... 2017 , ... The Women’s Choice Award, a growing platform that gives a ... Women’s Choice Award. The identification by women of an effective new migraine relief ... are women. In a survey taken by the Women’s Choice Award organization, nine out ...
(Date:8/22/2017)... ... August 22, 2017 , ... Each of the past six years, Lightning Labels has ... of these labels and stickers, demonstrating the variety and creativity of their designs. Submissions this ... images came in. Now, it's time to announce the winners of the sixth annual Photo ...
(Date:8/22/2017)... ... August 22, 2017 , ... “To Walk Away”: a captivating and romantic ... Edward Koontz. “To Walk Away” is the creation of published author, Larry R. Sherman, ... hundred manuscripts in chemistry and religion, as well as four novels. , Though ...
(Date:8/22/2017)... ... , ... “Glimpses Of Light”: is a unique and thought inspiring guide ... creation of published author, J.M. Shepherd, a writer, teacher, traveler, and metaphysician, the author ... , Shepherd shares, “Love is one of the least understood and yet most sought-after ...
Breaking Medicine News(10 mins):
(Date:8/17/2017)... EWING, N.J. , Aug. 17, 2017 Bio-Ess Laboratories, LLC ... to increase antibody titer and present new data on Cell-Ess® ... in Boston, MA August 21-25.  The Bioprocessing ... for today,s bioprocess challenges. ... Boost and Optimizer ...
(Date:8/15/2017)... , Aug. 15, 2017  AOTI Inc. announced today that ... Therapy Inc., has recently opened a New York City Office in ... usage of its unique Topical Wound Oxygen (TWO 2 ) homecare ... the Accreditation Commission for Health Care (ACHC) under the company,s DMEPOS ... ...
(Date:8/8/2017)... Second-quarter 2017 revenues of $876 million and ... operations Second-quarter 2017 Branded ... Second-quarter 2017 Sterile Injectables ... Second-quarter 2017 adjusted diluted earnings per ... $0.93 Second-quarter 2017 reported ...
Breaking Medicine Technology: