Navigation Links
Multiple Regions of the Brain Locate Pain

Spatial aspects of pain, an important component of diagnosis, are now revealed to be processed by many more areas of the brain, than previously thought.//

Spatial aspects of pain are a common problem in diagnosis, said Robert Coghill, Ph.D., senior researcher on the study and a neuroscientist at Wake Forest University School of Medicine. Patients cannot always distinguish pain from indigestion and pain from a heart attack, for example. Pain from a nerve injury is often felt at sites other than at the injury. And, in some cases, an injury on one side of the body results in pain on both sides.

“The scientific understanding of spatial aspects of pain is so limited that patients with widespread pain may get sent to a psychiatrist rather than a pain clinic,” said Coghill.

“This study expands our notion of where in the brain the ‘where’ component of pain is processed – it’s not as simple as we thought,” said Coghill. “Brain mechanisms that process the location of pain now appear to be highly similar to those that process the location for hearing and vision.”

The new finding published this week in the Journal of Neuroscience – that multiple regions of the brain are involved in determining pain location – was achieved with functional magnetic resonance imaging (MRI), a technique that shows brain activity while a task is being performed. The study involved 12 healthy volunteers from ages 22 to 39. Two thermal stimulators were placed between 1.5 and 6 inches apart on each participant’s lower leg. While participants were undergoing a functional MRI, one of the stimulators was activated at a temperature between 95 and 120 degrees. Then, after a 30-second rest period, one of stimulators was activated. Participants were told to push a button to indicate whether the second activation was in the same or a different location from the first.

According to conventional wisdom, a few brain regions, including the primary somatosensor y cortex, are involved in determining pain location, said lead author Yoshitetsu Oshiro, M.D., Ph.D. But the MRI testing showed that other areas, known as the medial pain system and thought to be involved in the emotional aspects of pain, were also used.

“This was very surprising,” said Oshiro. “Pain isn’t well understood and better treatments are needed. This shift in direction will be important to move research and treatments in the right direction.”

Coghill agreed. “A whole network of brain areas were lighting up while subjects were evaluating the spatial location of the stimulus,” he said. “We’re showing something very new and different: areas thought historically to be involved in processing the emotional aspects of pain were involved in determining pain location. It gives us a whole new conceptual framework for thinking about spatial aspects of pain.”

He said the study suggests that a lot of our sensory experiences are built by comparing incoming information with previously experienced information. “That convergence of information gives us a full sensory experience of the information coming in from our nervous systems.”

ource-Eurekalert
ANN
'"/>




Related medicine news :

1. Naked DNA Vaccination May Conquer Arthritis and Multiple Sclerosis
2. Multiple organ disease cured by genes
3. Adult stem cells in treatment for Multiple sclerosis (MS)
4. Life Quality For Patients With Multiple Sclerosis
5. Effective Pain Relief For Patients Suffering From Multiple Sclerosis
6. The Link Between Hepatitis B Vaccine And Multiple Sclerosis Questioned
7. Hope For Patients With Multiple Sclerosis
8. Individuals Born In May At A Higher Risk Of Developing Multiple Sclerosis
9. Debating The Link Between Sex Hormones And Multiple Sclerosis
10. Warning Issued by FDA on consumption of the drug Tysabri used to treat Multiple Sclerosis
11. Decreasing Multiple Births By Single Embryo Transfers
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2016)... , ... June 25, 2016 , ... Austin residents seeking ... American College of Mohs Surgery and to Dr. Russell Peckham for medical and surgical ... effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... ... athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as ... City area —Johnson is one of the first doctors to perform the treatment. ...
(Date:6/24/2016)... ... 2016 , ... June 19, 2016 is World Sickle Cell Observance Day. In ... benefits of holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued ... Sickle Cell Disease (SCD) is a disorder of the red blood cells, which can ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, CA is excited ... To Recovery® program to drive cancer patients to and from their cancer treatments. ... highest quality of life and ongoing independence. Getting to and from medical treatments ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... client, The Grove Investment Group (TGIG), has initiated cultivation and processing operations at ... Las Vegas and Pahrump, Nevada. , Puradigm is the manufacturer of a complete ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... June 23, 2016 Research and Markets ... Issue 52" report to their offering. ... treatment creates a favourable commercial environment for MedImmune to enter. ... base that will serve to drive considerable growth for effective ... serve to cap sales considerably, but development is still in ...
(Date:6/23/2016)... , , , WHEN: ... , , , , LOCATION: , , , Online, with ... , EXPERT PANELISTS:  , , , Frost & Sullivan,s Global Vice ... Senior Industry Analyst, Divyaa Ravishankar and Unmesh Lal, Program Manager , ... industry is witnessing an exceptional era. Several new demand spaces, such ...
(Date:6/23/2016)... Colombia , June 23, 2016  Astellas today announced the establishment of Astellas Farma Colombia (AFC), a new ... affiliate in Latin America . ... ... ... ...
Breaking Medicine Technology: