Navigation Links
Mouse Model Demonstrates Immune System Reaction In Chlamydia Infection

Microbiology and Molecular Genetics identified one of the Chlamydia proteins recognized by T cells during infection and engineered mice where all the T cells in the mice exclusively respond to this Chlamydia protein. These mice are known as T cell receptor transgenic (TCRtg) mice and have none of the T cell diversity found in a normal mouse. Starnbach and his team harvested T cells from the Chlamydia-specific TCRtg mice, labeled them with a dye, and injected them into normal mice. By boosting the number of Chlamydia-specific T cells in the recipient mice, they were able to identify and monitor them as they responded to infection.

"We found that when the recipient mice were infected with Chlamydia, the labeled T cells became activated specifically in the lymph nodes near the reproductive tract, expanded in number in those lymph nodes, and migrated into the mucosa lining the genital tract," Starnbach said. "We also found that the T cells recruited to the genital mucosa secrete gamma interferon as they respond to Chlamydia infection. Gamma interferon secretion has been described as the key molecule T cells use to rid the body of Chlamydia."

The findings show how T cell responses can be studied in reproductive tissues, which is likely to reveal avenues to the development of vaccines against Chlamydia, and possibly other STDs.

"In this report, we identify one candidate protein, Cta1, and show that T cells specific for Cta1 can reduce Chlamydia infection," Starnbach said. "In designing a vaccine, we would want to make sure the vaccine stimulates T cells with characteristics that cause them to home to the genital tract - the site of infection. We also would want them to respond with the same arsenal of protective factors – such as the secretion of gamma interferon that we show occurs using our TCRtg tools."

The goal of vaccines is to stimulate a response that mimics exposure to a pathogen, without the risks of actual infecti
'"/>




Page: 1 2 3

Related medicine news :

1. Mouse Allergen Found In Homes Could Trigger Asthma In Kids
2. Researchers Develop Mouse Model Of Brain Tumor
3. German Scientists Create Stem Cells From Mouse Testes
4. Mouse Models To Determine The Cause Of Aggressive Leukemia
5. Mouse Model Beneficial to Study of Head and Neck Cancer
6. Scientists Discover New RNAs in Mouse Testicles
7. Scientists Isolate Leukemia Stem Cells in Mouse Model
8. Mouse Gene With Gene Stutter Will Help Leukemia Research
9. Rett Syndrome Reversed in Genetic Mouse Model
10. Treatment Extends Survival in Mouse Model of Spinal Muscular Atrophy
11. Mouse Study Suggests Anxiety Disorders Take Root in Infancy
Post Your Comments:
(Date:7/29/2014)... July 29, 2014 PeopleKeys today announced ... to teach students how to train and certify others ... Certified Behavioral Consultant Trainer , will be taught by ... of Training John Schindell as a live Tele-course over ... , The Certified Behavioral Consultant Trainer course will use ...
(Date:7/29/2014)... Guests at Napa Valley's quintessential luxury resort, Auberge ... experience. The top of each luxurious resort bed is adorned ... expertly crafted, 100% Egyptian cotton white duvets and pillow shams ... closer look, words are woven in the linens that serve ... , Intentional breathing and visualization are keys to relaxing ...
(Date:7/29/2014)... Septic tanks have a ... score reflects a buyer's moderate ability to negotiate lower ... suppliers, the product's widespread availability and the price-competitive nature ... Weinstein. IBISWorld estimates that there are more than 400 ... supplier options. However, recent demand growth and rising costs ...
(Date:7/29/2014)... 29, 2014 The Marietta cosmetic dentists ... teeth whitening for high school and college students heading ... The teeth whitening is a safe, professional strength system, as ... confidence for students at these important stages in life. , ... have never had their teeth whitened. "After braces, teeth ...
(Date:7/28/2014)... 2014 NAPW honors ... Hospital Center, as a 2014 Professional Woman of the ... for leadership in community health. As the largest, most-recognized ... every industry and profession, the National Association of Professional ... over 600,000 members and nearly 300 Local Chapters. , ...
Breaking Medicine News(10 mins):Health News:PeopleKeys Announces New Certified Behavioral Consultant Trainer Course 2Health News:PeopleKeys Announces New Certified Behavioral Consultant Trainer Course 3Health News:Auberge Du Soleil Offers INTENTIONS™ by Peacock Alley on Guests' Beds Providing a Unique Sleep Experience 2Health News:Septic Tanks Procurement Category Market Research Report Now Available from IBISWorld 2Health News:Septic Tanks Procurement Category Market Research Report Now Available from IBISWorld 3Health News:Septic Tanks Procurement Category Market Research Report Now Available from IBISWorld 4Health News:Back to School Teeth Whitening Extravaganza For High School Students and Collegiates During August 2014 2Health News:Back to School Teeth Whitening Extravaganza For High School Students and Collegiates During August 2014 3Health News:National Association of Professional Women Announces Pamela A. Schulters, Head Nurse at Kings County Hospital Center, a 2014 Professional Woman of the Year 2
... MNKD ), focused on discovering, developing and commercializing,treatments for ... following conferences: * The Acumen BioFin Rodman & Renshaw ... 6, 2007 at 2:20 PM ET at the New York ... * The CIBC 18th Annual Healthcare Conference on Wednesday November ...
... OTTR ) announced financial results for the quarter,ended September 30, ... of $302.2 million. -- Consolidated net income of $13.3 million ... with $13.5 million for the third quarter of 2006. -- ... 2007 compared with $0.45 for the third ...
... the inventor,of Pulse CO-Oximetry and Read-Through Motion and ... system-wide implementation of,Masimo SET pulse oximetry. Building on ... other areas of its network, CHN expanded the,adoption ... every site --,making Masimo SET CHN,s standard of ...
... retention, employee,engagement and retirement top the list of ... the Best Practices, LLC,s Global Benchmarking,Council. From executive-driven ... events, roundtable discussions and,information exchange teleconferences, proactive HR ... this year. As the year comes to ...
... ORLANDO, Fla., Nov. 1 The following is being,issued by Itamar Medical:, WHO: ... Rochester, MN ... Goteborg, Sweden ... Dr. Mark Pritzker, Cardiologist, ...
... Mass., Nov. 1, 2007 Researchers from the University of ... type 1 diabetes with dual grants from the Juvenile ... , The grants, which total $300,000, will support the ... Directed by Aldo A. Rossini, MD, the William and ...
Cached Medicine News:Health News:Otter Tail Corporation Announces Third Quarter Earnings and Maintains 2007 Earnings Guidance; Board of Directors Declares Dividend 2Health News:Otter Tail Corporation Announces Third Quarter Earnings and Maintains 2007 Earnings Guidance; Board of Directors Declares Dividend 3Health News:Otter Tail Corporation Announces Third Quarter Earnings and Maintains 2007 Earnings Guidance; Board of Directors Declares Dividend 4Health News:Otter Tail Corporation Announces Third Quarter Earnings and Maintains 2007 Earnings Guidance; Board of Directors Declares Dividend 5Health News:Otter Tail Corporation Announces Third Quarter Earnings and Maintains 2007 Earnings Guidance; Board of Directors Declares Dividend 6Health News:Otter Tail Corporation Announces Third Quarter Earnings and Maintains 2007 Earnings Guidance; Board of Directors Declares Dividend 7Health News:Otter Tail Corporation Announces Third Quarter Earnings and Maintains 2007 Earnings Guidance; Board of Directors Declares Dividend 8Health News:Otter Tail Corporation Announces Third Quarter Earnings and Maintains 2007 Earnings Guidance; Board of Directors Declares Dividend 9Health News:Otter Tail Corporation Announces Third Quarter Earnings and Maintains 2007 Earnings Guidance; Board of Directors Declares Dividend 10Health News:Otter Tail Corporation Announces Third Quarter Earnings and Maintains 2007 Earnings Guidance; Board of Directors Declares Dividend 11Health News:Otter Tail Corporation Announces Third Quarter Earnings and Maintains 2007 Earnings Guidance; Board of Directors Declares Dividend 12Health News:Otter Tail Corporation Announces Third Quarter Earnings and Maintains 2007 Earnings Guidance; Board of Directors Declares Dividend 13Health News:Otter Tail Corporation Announces Third Quarter Earnings and Maintains 2007 Earnings Guidance; Board of Directors Declares Dividend 14Health News:Otter Tail Corporation Announces Third Quarter Earnings and Maintains 2007 Earnings Guidance; Board of Directors Declares Dividend 15Health News:Community Health Network of Indianapolis Completes System-Wide Conversion to Masimo SET Pulse Oximetry Technology 2Health News:Community Health Network of Indianapolis Completes System-Wide Conversion to Masimo SET Pulse Oximetry Technology 3Health News:Community Health Network of Indianapolis Completes System-Wide Conversion to Masimo SET Pulse Oximetry Technology 4Health News:Retain Talent and Engage Employees in 2008 2Health News:How Early Can We Detect Cardiovascular Disease Less Expensively... Even in Childhood? 'PAT' is the Invisible Signal 2Health News:UMass Medical School receives $300,000 from JDRF and Iacocca Foundation 2
(Date:7/28/2014)... 28, 2014  MiMedx Group, Inc. (NASDAQ: MDXG ), ... biomaterials and bioimplants processed from human amniotic membrane, announced today ... Highlights include: , Revenue exceeds upper ... to $25.6 million , Quarter-over-quarter revenue ... revenue increases 181% over Q2 2013 and 40% sequentially over ...
(Date:7/28/2014)... Calif. , July 28, 2014 KaloBios ... an update on the status of the KB001-A development ... Sanofi Pasteur.  KB001-A Collaboration Update ... agreement with Sanofi Pasteur to regain all rights to ... licensing agreement entered into in 2010 has been terminated. ...
(Date:7/28/2014)... , July 28, 2014 Reportlinker.com announces ... in its catalogue: Portugal Pharmaceuticals ... http://www.reportlinker.com/p0207141/Portugal-Pharmaceuticals-and-Healthcare-Report-Q3-2014.html Includes ... View: Faster-than-expected economic growth last quarter has led ... slightly upwards. As forecast previously, BMI expects ...
Breaking Medicine Technology:MiMedx Announces Record Second Quarter Results 2MiMedx Announces Record Second Quarter Results 3MiMedx Announces Record Second Quarter Results 4MiMedx Announces Record Second Quarter Results 5MiMedx Announces Record Second Quarter Results 6MiMedx Announces Record Second Quarter Results 7MiMedx Announces Record Second Quarter Results 8MiMedx Announces Record Second Quarter Results 9MiMedx Announces Record Second Quarter Results 10MiMedx Announces Record Second Quarter Results 11MiMedx Announces Record Second Quarter Results 12MiMedx Announces Record Second Quarter Results 13MiMedx Announces Record Second Quarter Results 14MiMedx Announces Record Second Quarter Results 15MiMedx Announces Record Second Quarter Results 16MiMedx Announces Record Second Quarter Results 17MiMedx Announces Record Second Quarter Results 18KaloBios Provides Update on KB001-A Partnership and Clinical Status 2KaloBios Provides Update on KB001-A Partnership and Clinical Status 3KaloBios Provides Update on KB001-A Partnership and Clinical Status 4KaloBios Provides Update on KB001-A Partnership and Clinical Status 5KaloBios Provides Update on KB001-A Partnership and Clinical Status 6Portugal Pharmaceuticals and Healthcare Report Q3 2014 2Portugal Pharmaceuticals and Healthcare Report Q3 2014 3Portugal Pharmaceuticals and Healthcare Report Q3 2014 4
... Feb. 28, 2011 Glenveigh Medical, LLC and Monica ... rights in the United States as well as US ... fetal monitoring system. The system recently received FDA regulatory ... the trade name Beacon by Monica™ , the ...
... Pa., Feb. 28, 2011 ViroPharma Incorporated (Nasdaq: ... executive officer of ViroPharma, will present at the Citi 2011 ... 2, 2011.  The conference is being held at the Hilton ... Rowland, vice president and chief financial officer, of ViroPharma, will ...
Cached Medicine Technology:Glenveigh Medical and Monica Healthcare Announce Distribution Agreement for Groundbreaking FDA Cleared Wireless Fetal Monitoring System 2ViroPharma to Participate in Two March Healthcare Conferences 2
... power table has everything that you need ... new AIT-15 offers 20 mm of additional ... and locking castors to secure the table. ... for most any application. Use a double ...
If youre looking to expand your projection capabilities, without a major capital investment, consider Topcons CP-5D Chart Projector....
... all-metal Trial Frame that is durably constructed, ... design that extends the life of the ... of springs and other components. The leaf ... comfortably on the patients head. The Trial ...
Inquire...
Medicine Products: