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Morphine Withdrawal Complicates Hepatitis C Infection in Drug Abusers

tudy also throws light on explaining why so many HCV-infected patients fail to respond to IFN-alpha treatment.

These results suggest that opioid abusers experiencing periods of drug abuse, followed by periods of withdrawal (due to lack of supplies) may lead to immunocompromised liver. The study also underscores the necessity of future clinical and epidemiological studies to define the role of opiate abuse in promoting HCV disease. These findings further support the need for methadone maintenance treatment as an additional benefit for opioid abusers.
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