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More Than 270 Medicines in Testing for Heart Disease and Stroke

the development of effective medicines to control both blood pressure and cholesterol, according to officials at the NHLBI. In addition, treatment of heart attacks has vastly improved. Twenty-five years ago, the treatment for heart attacks was simply bed rest. Today, doctors have medicines that can stop a heart attack in mid-stream as well as other high-tech treatments.

According to the report, the medicines in development include 30 for heart failure, which kills more than 50,000 Americans a year; 31 for high blood pressure, a leading risk factor for both heart disease and stroke; 19 for heart attacks, which strike more than 800,000 Americans a year; and 19 for stroke, which afflicts about 700,000 Americans each year. Many of the potential medicines use cutting-edge technologies and new scientific approaches. For example:

Human stem cells that may restore cardiac function by forming new heart muscle.
A new anticoagulant that regulates clot formation to prevent stroke in atrial fibrillation.
A vaccine that may be able to promote 'good' cholesterol by preventing the transfer of 'good' cholesterol to 'bad' cholesterol.


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