Navigation Links
Moles become cancerous due to genes

According to new study, researchers have identified a gene that causes benign moles on the skin to become cancerous. This could allow doctors to treat more effectively patients with early stages of melanoma. A team of scientists lead by Dr. Rhoda Alani of Johns Hopkins University, found a gene known as Id1 that causes cancer cells to grow in melanoma. Id1 blocks a tumor suppressor gene that ordinarily keeps precancerous moles from progressing to melanoma or skin cancer.// The study found that high levels of the Id1 protein were expressed only in the first stages of melanoma when the disease lies on the surface of skin.

According to the American Cancer Society, patients who have melanoma that has not spread below the skin have a survival rate of 97 percent beyond five years. But as the tumor begins to grow, the survival rate falls to 50 percent if it has reached the lymph nodes below the skin and 20 percent if it has spread to other organs in the body. On a larger scale, this will be very useful in the early diagnosis and cure of the disease.

According to researchers a person's risk of melanoma is influenced by: * family history * exposure to the sun * number of moles *sensitivity of the skin Researchers studied Id1 protein levels in 21 human tissue samples including precancerous moles and various stages of melanoma. Accorind to Journal, diagnostic tools could be designed to monitor Id1 because it is only activated in early stages of melanoma, and not precancerous moles or later stages of the disease.

Id1 also may cause various mutations to occur in the cancer cells, making the suppressor gene damaged beyond repair. As the cancer grows, researchers reason, Id1 levels decrease because it is no longer needed to block the suppressor gene.

According to Alani a larger study of several hundred patients will be conducted in order to verify the Id1 gene's role in melanoma before designing a method to test for it. This is important because the diagnosis of melanoma is very difficult and treatment varies based on the degree to which it has progressed. Physicians generally have a difficult time determining if a mole is cancerous. She feels that by developing a test to monitor for the presence of Id1, doctors will be able to better treat patients with the disease.

She said that Melanoma tumors spread very quickly, and the best treatment is to surgically remove the cancer because patients have not responded well to chemotherapy and radiation treatments.


'"/>




Related medicine news :

1. Moles Among The Older Generation May Be Dangerous
2. Indian Doctor in Britain Jailed for Molesting Patients
3. Why Don’t All Moles Progress to Melanoma
4. Photo Therapy to Treat Neonatal Jaundice may Cause Moles
5. Computers may become surgeons
6. Barcodes to become newborns ID
7. Diabetes could become an epidemic
8. Teenagers may become violent after watching aggressive acts
9. Influenza Avian Flu strain has become more contagious and dangerous.
10. Gene causes moles to become cancerous
11. Sensitive teeth could become bad memories
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... ... June 27, 2016 , ... A ... revolutionize the emergency ambulance transport experience for the millions of people who require ... has disrupted the taxi industry through the use of technology. Now, SmartEMS has ...
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements owned ... developed to enhance the health of felines. The formula is all-natural and is made ... in the PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus Root ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... The temporary closing of Bruton Memorial Library ... City Observer , brings up a new, often overlooked aspect of head lice: the parasite’s ... for fumigation is not a common occurrence, but a necessary one in the event that ...
(Date:6/25/2016)... ... 2016 , ... On Friday, June 10, Van Mitchell, Secretary of the Maryland ... iHire in recognition of their exemplary accomplishments in worksite health promotion. , The Wellness ... & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was one of ...
(Date:6/24/2016)... ... 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was out of ... verbally and physically. , “When something upset him, he couldn’t control his emotions,” remembers Marcy. ... throw rocks at my other children and say he was going to kill them. ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... VEGAS , June 26, 2016 ... to value-based care operating models within the health care ... enable greater financial efficiency , Deloitte offers a ... the key business issues impacting efficient cost optimization: labor ... , These services facilitate better outcomes and better ...
(Date:6/24/2016)... FRANCISCO, Calif. , June 24, 2016 /PRNewswire/ ... ), a biopharmaceutical company developing novel therapeutics for ... unmet needs, today announced the closing of its ... of common stock, at the public offering price ... in the offering were offered by GBT. GBT ...
(Date:6/24/2016)... , June 24, 2016 ... of the "Structural Electronics 2015-2025: Applications, Technologies, ... In-Mold Electronics, Smart Skin, ... Photovoltaics Structural electronics involves electronic ... load-bearing, protective structures, replacing dumb structures such as ...
Breaking Medicine Technology: