Navigation Links
Molecule responsible for muscle repair identified

Skeletal muscles repair by themselves from injuries. However at times due to age or disease these muscles are not able to heal itself.// Researchers have identified a molecule that when is deficient, is actually helpful to muscle regeneration.

Researchers from University of Illinois-Chicago had reported in their findings that deficient plasminogen activator inhibitor-1 (PAI-1) promotes muscle regeneration and this may be targeted to treatment in cases of muscle degeneration due to age or disease. The plasminogen system has multiple functions and act together with the growth factors, inflammatory factors and other systems.

Investigators have found in parallel animal studies that mice, which were lacking in the PAI-1, had increased activity of an enzyme called urokinase-type plasminogen activator in the damaged muscle. This had resulted in increase in proteins like the myogenic transcription factor MyoD that had led to faster muscle regeneration and repair after injury.

Muscle regeneration after injury is important and when this does not happen due to disease or age, it may lead to muscles not being able to recover from damage due to exercise, surgery of trauma. Also disease conditions like Duchenne Muscular Dystrophy and other muscular degenerative disease may hinder the normal muscle regeneration.

Reference: American Journal of Physiology-Cell Physiology, July 2005
'"/>




Page: 1

Related medicine news :

1. New Molecule that can stop the growth of Viruses
2. Puberty may be due to GPR54 gene and KiSS-1 Molecule
3. Molecule aids fight E. Coli Infections
4. Molecule That Aids Bacterial Infections Identified
5. Molecule Behind Multiple Sclerosis Discovered
6. Therapeutic Monoclonal Antibody Production Is More Profitable Than Small Molecule Drugs
7. Scientists Discover Prostate Cancer Triggering Molecule
8. Passion Fizzling Out? Blame The “Love Molecule
9. Sensor Can Detect "Unhealthy" Molecules In Breath
10. Polymer Molecule Layered On Carb Molecule to Increase Sensitivity
11. Discovery Of New Molecule Could Solve Cancer Spread Mystery
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/26/2016)... Carolina (PRWEB) , ... June 26, 2016 , ... ... of a new product that was developed to enhance the health of felines. The ... centuries. , The two main herbs in the PawPaws Cat Kidney Support ...
(Date:6/25/2016)... FL (PRWEB) , ... June 25, 2016 , ... The temporary closing of Bruton Memorial ... Plant City Observer , brings up a new, often overlooked aspect of head lice: the ... closing for fumigation is not a common occurrence, but a necessary one in the event ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary of ... award to iHire in recognition of their exemplary accomplishments in worksite health promotion. , ... Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. Her son ... lash out at his family verbally and physically. , “When something upset him, he couldn’t ... would use it. He would throw rocks at my other children and say he was ...
(Date:6/24/2016)... ... ... Inc, makers of Topricin and MyPainAway Pain Relief Products, join The ‘Business for a Fair ... hour by 2020 and then adjusting it yearly to increase at the same rate as ... the wage floor does not erode again, and make future increases more predictable. , The ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016 Research and Markets has announced ... report to their offering. ... a favourable commercial environment for MedImmune to enter. The US ... will serve to drive considerable growth for effective anti-influenza medications. ... cap sales considerably, but development is still in its infancy. ...
(Date:6/23/2016)... MOUNTAIN VIEW, Calif. , June 23, 2016 ... 9:00 a.m. CST on Thursday, July 7, 2016 , , ... kayla.belcher@frost.com ) , , , , EXPERT PANELISTS:  ... Sciences, Nitin Naik; Senior Industry Analyst, Christi Bird; Senior Industry Analyst, ... The global pharmaceutical industry is witnessing ...
(Date:6/23/2016)... , June 23, 2016  Astellas today announced the establishment of Astellas Farma Colombia (AFC), a new affiliate ... in Latin America . ... ... ... ...
Breaking Medicine Technology: