Navigation Links
Molecule responsible for muscle repair identified

Skeletal muscles repair by themselves from injuries. However at times due to age or disease these muscles are not able to heal itself.// Researchers have identified a molecule that when is deficient, is actually helpful to muscle regeneration.

Researchers from University of Illinois-Chicago had reported in their findings that deficient plasminogen activator inhibitor-1 (PAI-1) promotes muscle regeneration and this may be targeted to treatment in cases of muscle degeneration due to age or disease. The plasminogen system has multiple functions and act together with the growth factors, inflammatory factors and other systems.

Investigators have found in parallel animal studies that mice, which were lacking in the PAI-1, had increased activity of an enzyme called urokinase-type plasminogen activator in the damaged muscle. This had resulted in increase in proteins like the myogenic transcription factor MyoD that had led to faster muscle regeneration and repair after injury.

Muscle regeneration after injury is important and when this does not happen due to disease or age, it may lead to muscles not being able to recover from damage due to exercise, surgery of trauma. Also disease conditions like Duchenne Muscular Dystrophy and other muscular degenerative disease may hinder the normal muscle regeneration.

Reference: American Journal of Physiology-Cell Physiology, July 2005
'"/>




Page: 1

Related medicine news :

1. New Molecule that can stop the growth of Viruses
2. Puberty may be due to GPR54 gene and KiSS-1 Molecule
3. Molecule aids fight E. Coli Infections
4. Molecule That Aids Bacterial Infections Identified
5. Molecule Behind Multiple Sclerosis Discovered
6. Therapeutic Monoclonal Antibody Production Is More Profitable Than Small Molecule Drugs
7. Scientists Discover Prostate Cancer Triggering Molecule
8. Passion Fizzling Out? Blame The “Love Molecule
9. Sensor Can Detect "Unhealthy" Molecules In Breath
10. Polymer Molecule Layered On Carb Molecule to Increase Sensitivity
11. Discovery Of New Molecule Could Solve Cancer Spread Mystery
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/21/2017)... PA (PRWEB) , ... April 21, 2017 , ... ... firm in Allegheny County that offers services to communities throughout the greater Pittsburgh ... in a charity drive to provide adaptive bicycles for differently-abled children. , Variety ...
(Date:4/21/2017)... ... ... The Patient Advocacy Community of The Beryl Institute presented Eve DeVaro, Director, ... Advocacy Award in recognition of her extraordinary contributions to the field of patient ... Beryl Institute’s annual Patient Experience Conference on March 20 in Denver, Colorado. ...
(Date:4/21/2017)... ... 21, 2017 , ... Crossover Symmetry , an evidence ... active lifestyle company that provides Human Performance Training and education to tactical athletes. ... responders, military officers and others in service through the development and conditioning of ...
(Date:4/21/2017)... ... 2017 , ... Airway Management, the medical device manufacturer of ... and well renowned Asian distributor, Discovery Sleep. The agreement involves the ... and will stabilize and strengthen Airway’s presence with a dedicated, reputable medical device ...
(Date:4/21/2017)... ... April 21, 2017 , ... ... candidates to serve on its Accreditation and Standards Committees to support the ... is improving image quality and reducing patient radiation dose,” reports Eliot Siegel, ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... , April 19, 2017  New research provides evidence that ... Parkinson,s, according to a study released today that will be ... Meeting in Boston , April 22 ... the treatment of Parkinson,s disease, the oral drug levodopa has ... and longevity. But as the disease progresses, the effects of ...
(Date:4/18/2017)... Ohio , April 18, 2017  Cardinal Health ... Non-GAAP 1 fiscal 2017 earnings per share (EPS) ... and 2019.  This is in conjunction with this morning,s ... Deep Vein Thrombosis and Nutritional Insufficiency businesses. ... from continuing operations will be at the bottom of ...
(Date:4/18/2017)... 2017 Research and Markets has announced the ... to their offering. ... arthroscopy devices market to grow at a CAGR of 6.35% during ... Market 2017-2021, has been prepared based on an in-depth market analysis ... and its growth prospects over the coming years. The report also ...
Breaking Medicine Technology: