Navigation Links
Molecule responsible for muscle repair identified

Skeletal muscles repair by themselves from injuries. However at times due to age or disease these muscles are not able to heal itself.// Researchers have identified a molecule that when is deficient, is actually helpful to muscle regeneration.

Researchers from University of Illinois-Chicago had reported in their findings that deficient plasminogen activator inhibitor-1 (PAI-1) promotes muscle regeneration and this may be targeted to treatment in cases of muscle degeneration due to age or disease. The plasminogen system has multiple functions and act together with the growth factors, inflammatory factors and other systems.

Investigators have found in parallel animal studies that mice, which were lacking in the PAI-1, had increased activity of an enzyme called urokinase-type plasminogen activator in the damaged muscle. This had resulted in increase in proteins like the myogenic transcription factor MyoD that had led to faster muscle regeneration and repair after injury.

Muscle regeneration after injury is important and when this does not happen due to disease or age, it may lead to muscles not being able to recover from damage due to exercise, surgery of trauma. Also disease conditions like Duchenne Muscular Dystrophy and other muscular degenerative disease may hinder the normal muscle regeneration.

Reference: American Journal of Physiology-Cell Physiology, July 2005
'"/>




Page: 1

Related medicine news :

1. New Molecule that can stop the growth of Viruses
2. Puberty may be due to GPR54 gene and KiSS-1 Molecule
3. Molecule aids fight E. Coli Infections
4. Molecule That Aids Bacterial Infections Identified
5. Molecule Behind Multiple Sclerosis Discovered
6. Therapeutic Monoclonal Antibody Production Is More Profitable Than Small Molecule Drugs
7. Scientists Discover Prostate Cancer Triggering Molecule
8. Passion Fizzling Out? Blame The “Love Molecule
9. Sensor Can Detect "Unhealthy" Molecules In Breath
10. Polymer Molecule Layered On Carb Molecule to Increase Sensitivity
11. Discovery Of New Molecule Could Solve Cancer Spread Mystery
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/26/2017)... (PRWEB) , ... May 26, 2017 , ... Mediaplanet is ... Wound Care" campaign in USA Today, which will educate readers on how to take ... the campaign, a large focus is placed on melanoma. Dancing with the Stars professional, ...
(Date:5/26/2017)... Clara, Calif. (PRWEB) , ... May 26, 2017 ... ... announces the integration of the CareFusion NOX-T3 portable sleep monitor with its Somnoware ... provides a consistent, browser-based interface for diagnostic device operations. With this platform, initializing ...
(Date:5/26/2017)... , ... May 26, 2017 , ... After raising nearly ... Top gadget will continue to be available at a discounted crowdfunding price on ... stress wherever they are, I also wanted to bring a fidget toy to the ...
(Date:5/26/2017)... , ... May 26, 2017 , ... “When the Stars ... Home” is the creation of published author Laura Weigel Douglas, an avid reader who ... in a house that sometimes feels like Green Hills Adventure Camp. She couldn’t be ...
(Date:5/26/2017)... ... , ... Water damage to the flooring of several classrooms at The Fort ... with a number of critical issues to address before students could return to classes. ... little or no disruption to class schedules. Second, the project had to comply with ...
Breaking Medicine News(10 mins):
(Date:5/11/2017)... 11, 2017  Thornhill Research Inc. ( ... an $8,049,024 USD five-year, firm-fixed-priced, indefinite-quantity/indefinite-delivery contract by ... Commercial Corporation (CCC) ( Ottawa, Ontario, Canada ... administer general anesthesia to patients requiring emergency medical ... US Marine Corps have been a longtime partner ...
(Date:5/10/2017)... , May 10, 2017 Radiology has become ... its costs have also spiraled to the number one ... to radiology than ever before as the most complete ... a patient with lower back pain an MRI may ... reason for pain, resulting in entirely different treatment protocols.  ...
(Date:5/9/2017)... , May 9, 2017  Oramed Pharmaceuticals Inc. ... a clinical-stage pharmaceutical company focused on the development ... the Canadian Intellectual Property Office has granted Oramed ... Administration of Exenatide". The patent covers Oramed,s invention ... GLP-1 is an incretin hormone that stimulates ...
Breaking Medicine Technology: