Navigation Links
Molecule responsible for muscle repair identified

Skeletal muscles repair by themselves from injuries. However at times due to age or disease these muscles are not able to heal itself.// Researchers have identified a molecule that when is deficient, is actually helpful to muscle regeneration.

Researchers from University of Illinois-Chicago had reported in their findings that deficient plasminogen activator inhibitor-1 (PAI-1) promotes muscle regeneration and this may be targeted to treatment in cases of muscle degeneration due to age or disease. The plasminogen system has multiple functions and act together with the growth factors, inflammatory factors and other systems.

Investigators have found in parallel animal studies that mice, which were lacking in the PAI-1, had increased activity of an enzyme called urokinase-type plasminogen activator in the damaged muscle. This had resulted in increase in proteins like the myogenic transcription factor MyoD that had led to faster muscle regeneration and repair after injury.

Muscle regeneration after injury is important and when this does not happen due to disease or age, it may lead to muscles not being able to recover from damage due to exercise, surgery of trauma. Also disease conditions like Duchenne Muscular Dystrophy and other muscular degenerative disease may hinder the normal muscle regeneration.

Reference: American Journal of Physiology-Cell Physiology, July 2005
'"/>




Page: 1

Related medicine news :

1. New Molecule that can stop the growth of Viruses
2. Puberty may be due to GPR54 gene and KiSS-1 Molecule
3. Molecule aids fight E. Coli Infections
4. Molecule That Aids Bacterial Infections Identified
5. Molecule Behind Multiple Sclerosis Discovered
6. Therapeutic Monoclonal Antibody Production Is More Profitable Than Small Molecule Drugs
7. Scientists Discover Prostate Cancer Triggering Molecule
8. Passion Fizzling Out? Blame The “Love Molecule
9. Sensor Can Detect "Unhealthy" Molecules In Breath
10. Polymer Molecule Layered On Carb Molecule to Increase Sensitivity
11. Discovery Of New Molecule Could Solve Cancer Spread Mystery
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/24/2016)... ... 2016 , ... United Benefit Advisors (UBA), the nation’s leading ... & Co., Inc. Headquartered in Albany, New York, Austin & Co., Inc. ... and beyond. As an employee-owned company celebrating over 160 years of service, ...
(Date:5/24/2016)... CO (PRWEB) , ... May 24, 2016 , ... ... tied to family wealth and to housing, with more advantaged communities providing richer ... proposed five types of interventions: (a) school improvement policies; (b) school choice policies; ...
(Date:5/24/2016)... ... May 24, 2016 , ... How to Write Error Free Procedures, **Presented by ... , Human error is known to be the major cause of quality and production ... totally eliminated, many human performance problems can be prevented. , How to Write Error ...
(Date:5/24/2016)... ... ... Mental health watchdog Citizens Commission on Human Rights (CCHR) of ... Thomas Szasz, is continuing its protest against the use of electroshock (ECT) on children ... The opening of the exhibit follows CCHR’s recent protest at the annual convention of ...
(Date:5/24/2016)... ... (PRWEB) May 24, 2016 -- Grow Healthy Vending, LLC ... Joining the Grow Healthy Advisory Board team are Amanda Katchka, ... mission of our organization and bring talent, expertise and energy to ... continue to expand our footprint as the leader in healthy vending,” ...
Breaking Medicine News(10 mins):
(Date:5/23/2016)... 23, 2016 Diplomat Pharmacy, Inc. (NYSE: DPLO) announced ... Internship programs. The hands-on learning experience is a 12-week ... paid Fellowship and Internship programs ... Fellows and interns are provided optional housing free of ... at the Riverfront Residence Hall to foster communication ...
(Date:5/23/2016)... According to market research ... and Demand Forecast to 2022 - Industry Insights ... (Drug Discovery and Development, Proteomics, Clinical Testing, Environment ... and Biotechnology, Academic and Research Institute, Hospitals and ... mass spectrometry market was valued at ...
(Date:5/23/2016)... The World Health Organization (WHO) expanded the Intended Use of ... 13 years, and above. Effective immediately, the PrePex device, manufactured ... males in the 14 priority countries in Southern and ... circumcision device to receive WHO Prequalification on 31 May 2013. ... " The expanded use of PrePex for younger ...
Breaking Medicine Technology: