Navigation Links
Molecule responsible for muscle repair identified

Skeletal muscles repair by themselves from injuries. However at times due to age or disease these muscles are not able to heal itself.// Researchers have identified a molecule that when is deficient, is actually helpful to muscle regeneration.

Researchers from University of Illinois-Chicago had reported in their findings that deficient plasminogen activator inhibitor-1 (PAI-1) promotes muscle regeneration and this may be targeted to treatment in cases of muscle degeneration due to age or disease. The plasminogen system has multiple functions and act together with the growth factors, inflammatory factors and other systems.

Investigators have found in parallel animal studies that mice, which were lacking in the PAI-1, had increased activity of an enzyme called urokinase-type plasminogen activator in the damaged muscle. This had resulted in increase in proteins like the myogenic transcription factor MyoD that had led to faster muscle regeneration and repair after injury.

Muscle regeneration after injury is important and when this does not happen due to disease or age, it may lead to muscles not being able to recover from damage due to exercise, surgery of trauma. Also disease conditions like Duchenne Muscular Dystrophy and other muscular degenerative disease may hinder the normal muscle regeneration.

Reference: American Journal of Physiology-Cell Physiology, July 2005
'"/>




Page: 1

Related medicine news :

1. New Molecule that can stop the growth of Viruses
2. Puberty may be due to GPR54 gene and KiSS-1 Molecule
3. Molecule aids fight E. Coli Infections
4. Molecule That Aids Bacterial Infections Identified
5. Molecule Behind Multiple Sclerosis Discovered
6. Therapeutic Monoclonal Antibody Production Is More Profitable Than Small Molecule Drugs
7. Scientists Discover Prostate Cancer Triggering Molecule
8. Passion Fizzling Out? Blame The “Love Molecule
9. Sensor Can Detect "Unhealthy" Molecules In Breath
10. Polymer Molecule Layered On Carb Molecule to Increase Sensitivity
11. Discovery Of New Molecule Could Solve Cancer Spread Mystery
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/25/2017)... ... July 25, 2017 , ... Therachat , a smart ... and providing demos of its smart journaling platform at the 125th American Psychological ... D.C. from August 3-6, 2017. , The APA Annual Convention is one of ...
(Date:7/25/2017)... WI (PRWEB) , ... July 25, 2017 , ... ... Aloria Health, as medical director. Dr. Negrette has more than a decade of ... She has worked closely with individuals fighting addictions, eating disorders, psychotic and manic ...
(Date:7/25/2017)... TX (PRWEB) , ... July 25, 2017 , ... SignatureCare ... emergencies in the Austin, TX area 24 Hours a day. , The ... Austin, TX. , “We’ve been open four months now and things are running ...
(Date:7/24/2017)... ... 2017 , ... Cheerag D. Upadhyaya , M.D., M.Sc., FAANS has been ... (SLMBNI), part of Saint Luke’s Health System . Dr. Upadhyaya has served in ... M.Sc., FAANS joins Stanley P. Fisher, M.D., who has served as medical ...
(Date:7/24/2017)... ... July 24, 2017 , ... BayMark Health Services ... Health Services Administration’s (SAMHSA) State Targeted Response to the Opioid Crisis program. ... will facilitate the development of a hub and spoke model for opioid treatment ...
Breaking Medicine News(10 mins):
(Date:7/13/2017)... , July 13, 2017 RK Logistics Group, ... of Pharmacy certification for its Fremont, CA ... solutions in the Tri-Valley and San Jose ... City of Fremont , with its Fremont Innovation ... to provide such a powerful resource to the hundreds of ...
(Date:7/12/2017)... INDIANAPOLIS , July 12, 2017  Eli Lilly and ... settlement agreement with generic companies to resolve pending patent litigation ... Virginia regarding the Cialis ® ... expire on April 26, 2020. As part of the agreement, ... on September 27, 2018. "The unit dose patent ...
(Date:7/11/2017)... 2017  The global market for liquid biopsy diagnostic ... million in 2016.  Although in early stages, the global ... particular as a result of the gradual shift towards ... introduction of a significant number of new liquid biopsy ... tumor biomarkers to guide treatment decisions. ...
Breaking Medicine Technology: