Navigation Links
'Missing Link' Stem Cells may Shorten Path to Therapies

. "Was is it the evolutionary divergence of mice and men, or was there a developmental explanation, reflecting different stages of growth?"

This question spurred Pedersen and his team to challenge conventional wisdom and see whether the bio-chemical conditions used to maintain human embryo stem cells might work for mice too.

Previous attempts had failed. But when the researchers applied the human-specific molecular cocktail to a later stage of the mouse embryo rather than the three-day old blastocyst stage from which stem cells had always been drawn, suddenly it worked.

"Comparative analyses suggest that the new cells may have more in common with human embryo stem cells" than the ones taken earlier in the life cycle from mice, commented Ian Chambers, the head of embryonic stem cell biology at the University of Edinburgh, in an e-mail.

"These are exciting findings that hint at ways in which it may be possible to alter the culture conditions for human embryo stem cells in order to make their maintenance more straightforward and malleable," he said after reviewing the studies.

Kevin Eggan, a researcher at the Harvard Stem Cell Institute, also welcomed the studies, saying they could "shed light on the origin and nature of human embryonic stem cells."

The discovery of the epiblast stem cells in mice should make it easier to isolate stem cells in other species, livestock, as well as mice genetically modified to express a disease so that it can be studied, the authors of the studies said.

The growth factor -- called activin/Nodal -- that is now known to work for humans and mice may also unlock access to stem cells in these other species, said Pedersen.

One persistent problem in trying to use stem cells to produce specialised cells for treatment -- to make insulin in the pancreas or beating-heart cells, for example -- is an extremely low efficiency.


'"/>




Page: 1 2 3

Related medicine news :

1. Gene linked to Missing Eye condition in newborns
2. Blood Cells Capable of Regenerating Liver
3. White Cells Count Can Predict Heart Attack Death Risk
4. Gene Therapy Destroys Pancreatic Cancer Cells
5. Stem Cells Have Few Mutations
6. Heart may pull Cells from Body to Self-repair
7. Cells critical for asthma development found
8. Vitamin D Wipes out Cancer Cells
9. Bone Marrow Cells Help Heart Attack Patients
10. Islet Cells May Lead to Diabetes CureChildren
11. Stem Cells Found To Offer Promise For Hair Growth
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Missing Link Stem Cells may Shorten Path Therapies

(Date:4/17/2014)... April 17, 2014-- Colic affects about one in five ... numerous pediatric visits during the first several months after ... symptoms was showing promise; however, the April 1, 2014 ... Sung, Valerie) reported on a study, "Probiotics and Infant ... L reuteri for infant colic did not ...
(Date:4/17/2014)... University School of Medicine (BUSM) have discovered that ... an experimental model. The findings, reported in the ... , may lead to more effective treatments for ... of the leading causes of illness and death ... impact by limiting the productivity of workers and ...
(Date:4/17/2014)... researchers at UC Davis has shown that the cyclin ... cell division, also boosts the mitochondrial activity to power ... has been shown to perform both jobs. This newfound ... control cellular energy production, potentially advancing cancer care and ... the journal Developmental Cell . , "These proteins ...
(Date:4/17/2014)... An international research team led by Cesar A. Arias, ... Center at Houston (UTHealth) has identified a new superbug ... The report appeared in the April 17 issue of ... The new superbug is part of a class of ... or MRSA, which is a major cause of hospital ...
(Date:4/17/2014)... days to find a colored ribbon representing a disease. A ... what color ribbon does one think of with lung cancer?, ... many suffering from the disease, black may be the only ... of lung cancer patients, primarily smokers between the ages of ... the stigma often felt by these patients, the emotional toll ...
Breaking Medicine News(10 mins):Health News:New study says probiotic use for infant colic is not effective in reducing symptoms 2Health News:BUSM researchers find anti-seizure drug may reduce alcohol consumption 2Health News:Dual role: Key cell division proteins also power up mitochondria 2Health News:New MRSA superbug emerges in Brazil 2Health News:Unraveling the 'black ribbon' around lung cancer 2
... , WASHINGTON, Dec. 8 The National Business Group on ... employers, announced today that Sally Welborn, Senior Vice President of ... Directors, effective immediately. , "We are thrilled to announce Sally,s ... Senior Vice President of Human Resources at Coca-Cola Enterprises ...
... , ... Technologies, Inc. , has been selected by the Blue Cross ... watchlist screening software for OFAC, OIG and EPLS and USA PATRIOT ... compliance software to BCBSA,s Chicago headquarters and its member Blue Cross ...
... , - May Set Stage ... Dec. 8 Neurology researchers have shown that feeding amino acids ... stage for the first effective treatment for cognitive impairments suffered by ... animal model that dietary intervention can restore a proper balance of ...
... panic disorder, study finds , TUESDAY, Dec. 8 (HealthDay ... in their blood might be at increased risk for ... , Researchers analyzed information on 1,987 adults, aged 20 ... Health and Nutrition Examination Survey between 1997 and 2004. ...
... defined as the pathological retrograde movement of gastric ... which may be important in reflux are observed ... disorder in these patients is ineffective esophageal motility ... been shown to be strongly associated with isolated ...
... to a lack of suitable studies, it is unclear ... autologous haematopoietic stem cell transplantation. With this type of ... are removed at a convenient time and generally re-implanted ... is neither indication nor proof of additional benefit compared ...
Cached Medicine News:Health News:National Business Group on Health Elects Sally Welborn, Walmart Executive, to Board of Directors 2Health News:The National Blue Cross and Blue Shield Association Selects ATTUS Technologies as Preferred Provider for OFAC, OIG, EPLS and USA PATRIOT Act Compliance 2Health News:The National Blue Cross and Blue Shield Association Selects ATTUS Technologies as Preferred Provider for OFAC, OIG, EPLS and USA PATRIOT Act Compliance 3Health News:With Amino Acid Diet, Mice Improve After Brain Injury 2Health News:With Amino Acid Diet, Mice Improve After Brain Injury 3Health News:Lead Exposure May Affect Mental Health 2Health News:Are manometric findings different between the patients with erosive and nonerosive disease? 2Health News:Autologous stem cell transplantation for soft tissue sarcoma: insufficient research into therapy 2Health News:Autologous stem cell transplantation for soft tissue sarcoma: insufficient research into therapy 3Health News:Autologous stem cell transplantation for soft tissue sarcoma: insufficient research into therapy 4
(Date:1/14/2014)... The Brandeis Medical Center, led by Dr. Emmanuel Brandeis , ... laser tattoo removal experience with the advanced Astanza Duality laser and ... quality cosmetic services with cutting edge medical technology and offering expert ... has seen a dramatic increase in the presence of ...
(Date:1/14/2014)... LEESBURG, Va. , Jan. 14, 2014 Animal Emergency Critical ... in Leesburg, Virginia is the first in ... hyperbaric oxygen chamber. Dr. Susan M. Barnes ... years. Dr. Barnes and husband, Dr. Cole Taylor , are ...
(Date:1/14/2014)... Inc. , a privately held company pioneering the development ... related neurodegenerative disorders, announced today the relocation of its ... as of January 15, 2014 and expanded lease agreement ... Oligomerix, which is focused on the development ...
Breaking Medicine Technology:Beverly Hills Physician Features Tattoo Removal with the Astanza Duality Laser, Offers $99 Special 2Hyperbaric Veterinary Medicine (hvm) Announces Animal Emergency Critical Care Installs A Small Animal Hyperbaric Chamber 2Oligomerix Relocates Corporate Headquarters and Secures Additional Laboratory Space from New York Medical College 2
... Corporation today announced the release of,new data concerning ... was conducted by the Department of Physiology at,University ... agreement with Millipore was announced in 2006. ,The ... research &,development scientist for Millipore’s Bioprocess Division, in,a ...
... June 20, 2007 /PRNewswire-FirstCall/ - SemBioSys,Genetics Inc. ... of,therapeutic proteins for metabolic and cardiovascular disease,today ... scientific poster and,abstract at the 67th Scientific ... Chicago. The Company's poster will disclose,recent accomplishments ...
Cached Medicine Technology:Millipore Corporation Announces New ReNcell Data from Collaboration,with ReNeuron 2Millipore Corporation Announces New ReNcell Data from Collaboration,with ReNeuron 3Millipore Corporation Announces New ReNcell Data from Collaboration,with ReNeuron 4SemBioSys to present new data at American Diabetes Association,annual meeting 2SemBioSys to present new data at American Diabetes Association,annual meeting 3
... 3 mirror lenses featuring ultra-clear Volk 3-Mirror ... 76°, 66° and 60°. The 3 ... well central and peripheral fundus viewing and ... angled to eliminate gaps in the visualized ...
... are a family of single-use direct view vitrectomy ... particular region of the retinal surface during eye ... 1 gram and is formed and polished to ... human cornea. Lenses come in boxes of 10 ...
... AFX Lens is a direct ... in an air-filled eye. In ... a primary air-fluid exchange vitrectomy ... sutureless design make it well ...
... Prism are designed for midperipherical ... for tractional retinal detachments (PDR, ... detachment. They can be used ... midperipheral laser applications. Direct image ...
Medicine Products: