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Michael J. Fox Foundation Awards $710,000 to Understanding of Parkinson's Disease Subtypes

edictive factors for reaching a common neuroprotective clinical trial endpoint -- time to disability requiring dopamine replacement therapy. She will use PRECEPT data to validate an earlier study she conducted in the DATATOP population. This previous study examined factors including smoking, disease duration, and tremor as an initial symptom.

Stephen Van Den Eeden, PhD, of the Kaiser Foundation Research Institute will assess predictive factors -- including age at diagnosis, gender, family history and race -- that may bear on mortality in Parkinson's disease.

Other funded studies will examine aspects of PD including whether it is possible to identify PD subgroups based on areas of disability (cognitive, balance, motor function) seen at the last available clinical visit; and factors (such as mood analysis, sleep, cognitive function and pain) that may contribute to the identification of novel PD subtypes.

Leadership funding for PD Subtypes was provided by the Kinetics Foundation of Los Altos, California. "We look forward to a continuing partnership between The Michael J. Fox Foundation for Parkinson's Research and the Kinetics Foundation as we work to improve PD diagnosis and treatment by characterizing disease subtypes," said Ken Kubota, Kinetics' director of programs.


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