Navigation Links
Michael J. Fox Foundation Awards $710,000 to Understanding of Parkinson's Disease Subtypes

NEW YORK, The Michael J. Fox Foundation for Parkinson's Research announced $710,000 in total funding to seven research teams for projects leveraging existing data and patient populations to initially characterize Parkinson's disease subtypes -- distinct forms of the disease that may differ in onset, progression and response to treatment.

"One of the most frustrating aspects of Parkinson's disease -- for patients, researchers and clinicians alike -- is the significant variability in how the disease manifests itself from patient to patient," said Sarah Orsay, chief executive officer of the Foundation.

"The retrospective studies funded under PD Subtypes aim to analyze data already gathered on different forms of the disease. This analysis could yield valuable information with potential to improve clinicians' ability to treat patients with existing therapies. It could also advance development of new treatments and enable better design of future clinical trials."

Applicants under PD Subtypes were required to propose research that would make use of existing data from well-characterized populations of Parkinson's patients. Several researchers will mine specific databases established by their own institutions for various purposes.

Others will work from some of the most important clinical research populations in the Parkinson's field, including the DATATOP (Deprenyl and Tocopherol Antioxidative Therapy of Parkinsonism) study population of 800 early-stage Parkinson's patients and the PRECEPT (Parkinson Research Examination of CEP-1347 Trial) population of 800 patients.

Nick Holford, MBChB, FRACP, of the University of Auckland will use a unique statistical approach to test the value of early measures of disease status in predicting the probable time to clinical events such as dementia, falls and depression.

Connie Marras, MD, PhD FRCP(C), of Toronto Western Hospital will focus on determining pr edictive factors for reaching a common neuroprotective clinical trial endpoint -- time to disability requiring dopamine replacement therapy. She will use PRECEPT data to validate an earlier study she conducted in the DATATOP population. This previous study examined factors including smoking, disease duration, and tremor as an initial symptom.

Stephen Van Den Eeden, PhD, of the Kaiser Foundation Research Institute will assess predictive factors -- including age at diagnosis, gender, family history and race -- that may bear on mortality in Parkinson's disease.

Other funded studies will examine aspects of PD including whether it is possible to identify PD subgroups based on areas of disability (cognitive, balance, motor function) seen at the last available clinical visit; and factors (such as mood analysis, sleep, cognitive function and pain) that may contribute to the identification of novel PD subtypes.

Leadership funding for PD Subtypes was provided by the Kinetics Foundation of Los Altos, California. "We look forward to a continuing partnership between The Michael J. Fox Foundation for Parkinson's Research and the Kinetics Foundation as we work to improve PD diagnosis and treatment by characterizing disease subtypes," said Ken Kubota, Kinetics' director of programs.


'"/>




Related medicine news :

1. Gest Says Will Reveal Damning Secrets On Michael Jackson
2. Where is Our Soul, Asks Michael Moore
3. Ask Right Questions and Save Country from Further Healthcare Crisis: Michael Moore
4. Woodruff Foundation Grant To Support Doctorate Of Nursing Practice Program
5. Kalam To Lay Foundation Of Vellore Research Center
6. Nippon Foundation To Help Leprosy Patients
7. Parents Launch SV40 Cancer Foundation In Memory of Son
8. Cancer Aid And Research Foundation: Offering Endless Hope To Cancer Patients
9. PM Launches Healthcare Foundation For India
10. Prime Minister Manmohan Singh, Flags Off Public Health Foundation of India
11. Gates Foundation to donate USD 104 million to TB Alliance
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... , ... October 13, 2017 , ... Ellevate Network, the ... business to advocate for action towards gender equality at their inaugural Summit in New ... the globe, and reached a social audience of over 3 million. To watch the ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a leader in ... awarded a contract by the Center for Medicare and Medicaid Services (CMS). The ... enterprise use of Agile methodologies in a consistent and high value manner across ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... treating sleep apnea using cutting-edge Oventus O2Vent technology. As many as ... disorder characterized by frequent cessation in breathing. Oral appliances can offer significant relief ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of Medical ... Friedman, PhD, FACMI, during the Opening Session of AMIA’s Annual Symposium in Washington, D.C. ... honor of Morris F. Collen, a pioneer in the field of medical informatics, this ...
(Date:10/12/2017)... ... , ... HMP , a leader in healthcare events and education, today announced ... Award for ‘Best B-to-B Healthcare Website.’ Winners were announced during the Eddie & Ozzie ... competition recognizes editorial and design excellence across a range of sectors. This year’s program ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... , Sept. 25, 2017  EpiVax, Inc., a ... design, and immune-engineering today announced the launch of ... development of personalized therapeutic cancer vaccines. EpiVax has ... exclusive access to enabling technologies to the new ... will lead EpiVax Oncology as Chief Executive Officer. ...
(Date:9/22/2017)... Md. , Sept. 22, 2017  As the ... Republican Senators Bill Cassidy (R-LA) and ... Information notes that the medical device industry is in ... medical device tax, the 2.3% excise tax on medical ... But they also want covered patients, increased visits and ...
(Date:9/19/2017)... a venture-backed medical device company developing a non-invasive, robotically assisted, platform therapy that uses pulsed ...   ... Jim Bertolina, ... Tom Tefft ... medical device executive Josh Stopek , PhD, who has led R&D and business development ...
Breaking Medicine Technology: