Navigation Links
Michael J. Fox Foundation Awards $710,000 to Understanding of Parkinson's Disease Subtypes

NEW YORK, The Michael J. Fox Foundation for Parkinson's Research announced $710,000 in total funding to seven research teams for projects leveraging existing data and patient populations to initially characterize Parkinson's disease subtypes -- distinct forms of the disease that may differ in onset, progression and response to treatment.

"One of the most frustrating aspects of Parkinson's disease -- for patients, researchers and clinicians alike -- is the significant variability in how the disease manifests itself from patient to patient," said Sarah Orsay, chief executive officer of the Foundation.

"The retrospective studies funded under PD Subtypes aim to analyze data already gathered on different forms of the disease. This analysis could yield valuable information with potential to improve clinicians' ability to treat patients with existing therapies. It could also advance development of new treatments and enable better design of future clinical trials."

Applicants under PD Subtypes were required to propose research that would make use of existing data from well-characterized populations of Parkinson's patients. Several researchers will mine specific databases established by their own institutions for various purposes.

Others will work from some of the most important clinical research populations in the Parkinson's field, including the DATATOP (Deprenyl and Tocopherol Antioxidative Therapy of Parkinsonism) study population of 800 early-stage Parkinson's patients and the PRECEPT (Parkinson Research Examination of CEP-1347 Trial) population of 800 patients.

Nick Holford, MBChB, FRACP, of the University of Auckland will use a unique statistical approach to test the value of early measures of disease status in predicting the probable time to clinical events such as dementia, falls and depression.

Connie Marras, MD, PhD FRCP(C), of Toronto Western Hospital will focus on determining pr edictive factors for reaching a common neuroprotective clinical trial endpoint -- time to disability requiring dopamine replacement therapy. She will use PRECEPT data to validate an earlier study she conducted in the DATATOP population. This previous study examined factors including smoking, disease duration, and tremor as an initial symptom.

Stephen Van Den Eeden, PhD, of the Kaiser Foundation Research Institute will assess predictive factors -- including age at diagnosis, gender, family history and race -- that may bear on mortality in Parkinson's disease.

Other funded studies will examine aspects of PD including whether it is possible to identify PD subgroups based on areas of disability (cognitive, balance, motor function) seen at the last available clinical visit; and factors (such as mood analysis, sleep, cognitive function and pain) that may contribute to the identification of novel PD subtypes.

Leadership funding for PD Subtypes was provided by the Kinetics Foundation of Los Altos, California. "We look forward to a continuing partnership between The Michael J. Fox Foundation for Parkinson's Research and the Kinetics Foundation as we work to improve PD diagnosis and treatment by characterizing disease subtypes," said Ken Kubota, Kinetics' director of programs.


'"/>




Related medicine news :

1. Gest Says Will Reveal Damning Secrets On Michael Jackson
2. Where is Our Soul, Asks Michael Moore
3. Ask Right Questions and Save Country from Further Healthcare Crisis: Michael Moore
4. Woodruff Foundation Grant To Support Doctorate Of Nursing Practice Program
5. Kalam To Lay Foundation Of Vellore Research Center
6. Nippon Foundation To Help Leprosy Patients
7. Parents Launch SV40 Cancer Foundation In Memory of Son
8. Cancer Aid And Research Foundation: Offering Endless Hope To Cancer Patients
9. PM Launches Healthcare Foundation For India
10. Prime Minister Manmohan Singh, Flags Off Public Health Foundation of India
11. Gates Foundation to donate USD 104 million to TB Alliance
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... ... 2016 , ... "FCPX editors can now reveal their media with growing colorful ... Christina Austin - CEO of Pixel Film Studios. , ProSlice Color brings the ... can now reveal the media of their split screens with growing colorful panels. , ...
(Date:6/27/2016)... , ... June 27, 2016 ... ... the patient payment industry today announced its strategic partnership with Connance, a ... workflows. , The two companies’ proven, proprietary technology combine to provide health ...
(Date:6/27/2016)... ... , ... TopConsumerReviews.com recently awarded their highest five-star rating to Best Buy Eyeglasses, ... the United States and Canada wear eyeglasses. Once considered to be a purely functional ... a fashion statement. Even celebrities use glasses as a way of creating an iconic ...
(Date:6/26/2016)... Battle Creek, Michigan (PRWEB) , ... June 26, 2016 , ... ... abuse, joined as sponsor of the 2016 Cereal Festival and World’s Longest Breakfast Table ... held in honor of the city’s history as home to some of the world’s ...
(Date:6/26/2016)... ... , ... PawPaws brand pet supplements owned by Whole Health Supply ... health of felines. The formula is all-natural and is made from Chinese herbs that ... Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract and Rehmannia Root ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... June 27, 2016  VMS Rehab Systems, Inc. ( ... take whatever measures required to build a strong and ... is currently listed on the OTC Markets-pink current trading ... and CEO, "We are seeing an anomaly in market ... not only by the Company, but shareholders and market ...
(Date:6/24/2016)...  Collagen Matrix, Inc., ("Collagen Matrix") the driving ... collagen and mineral based medical devices for tissue ... Messer has joined the company as Vice ... growing portfolio of oral surgery, neurosurgery, orthopaedic and ... the Collagen Matrix executive team as an accomplished ...
(Date:6/24/2016)... Dublin ... of the " Global Markets for Spectroscopy Equipment" ... This report focuses on the global ... including its applications in various applications. The report deals ... three main industries: pharmaceutical and biotechnology, food and beverage, ...
Breaking Medicine Technology: