Navigation Links
Michael J. Fox Foundation Awards $710,000 to Understanding of Parkinson's Disease Subtypes

NEW YORK, The Michael J. Fox Foundation for Parkinson's Research announced $710,000 in total funding to seven research teams for projects leveraging existing data and patient populations to initially characterize Parkinson's disease subtypes -- distinct forms of the disease that may differ in onset, progression and response to treatment.

"One of the most frustrating aspects of Parkinson's disease -- for patients, researchers and clinicians alike -- is the significant variability in how the disease manifests itself from patient to patient," said Sarah Orsay, chief executive officer of the Foundation.

"The retrospective studies funded under PD Subtypes aim to analyze data already gathered on different forms of the disease. This analysis could yield valuable information with potential to improve clinicians' ability to treat patients with existing therapies. It could also advance development of new treatments and enable better design of future clinical trials."

Applicants under PD Subtypes were required to propose research that would make use of existing data from well-characterized populations of Parkinson's patients. Several researchers will mine specific databases established by their own institutions for various purposes.

Others will work from some of the most important clinical research populations in the Parkinson's field, including the DATATOP (Deprenyl and Tocopherol Antioxidative Therapy of Parkinsonism) study population of 800 early-stage Parkinson's patients and the PRECEPT (Parkinson Research Examination of CEP-1347 Trial) population of 800 patients.

Nick Holford, MBChB, FRACP, of the University of Auckland will use a unique statistical approach to test the value of early measures of disease status in predicting the probable time to clinical events such as dementia, falls and depression.

Connie Marras, MD, PhD FRCP(C), of Toronto Western Hospital will focus on determining pr edictive factors for reaching a common neuroprotective clinical trial endpoint -- time to disability requiring dopamine replacement therapy. She will use PRECEPT data to validate an earlier study she conducted in the DATATOP population. This previous study examined factors including smoking, disease duration, and tremor as an initial symptom.

Stephen Van Den Eeden, PhD, of the Kaiser Foundation Research Institute will assess predictive factors -- including age at diagnosis, gender, family history and race -- that may bear on mortality in Parkinson's disease.

Other funded studies will examine aspects of PD including whether it is possible to identify PD subgroups based on areas of disability (cognitive, balance, motor function) seen at the last available clinical visit; and factors (such as mood analysis, sleep, cognitive function and pain) that may contribute to the identification of novel PD subtypes.

Leadership funding for PD Subtypes was provided by the Kinetics Foundation of Los Altos, California. "We look forward to a continuing partnership between The Michael J. Fox Foundation for Parkinson's Research and the Kinetics Foundation as we work to improve PD diagnosis and treatment by characterizing disease subtypes," said Ken Kubota, Kinetics' director of programs.


'"/>




Related medicine news :

1. Gest Says Will Reveal Damning Secrets On Michael Jackson
2. Where is Our Soul, Asks Michael Moore
3. Ask Right Questions and Save Country from Further Healthcare Crisis: Michael Moore
4. Woodruff Foundation Grant To Support Doctorate Of Nursing Practice Program
5. Kalam To Lay Foundation Of Vellore Research Center
6. Nippon Foundation To Help Leprosy Patients
7. Parents Launch SV40 Cancer Foundation In Memory of Son
8. Cancer Aid And Research Foundation: Offering Endless Hope To Cancer Patients
9. PM Launches Healthcare Foundation For India
10. Prime Minister Manmohan Singh, Flags Off Public Health Foundation of India
11. Gates Foundation to donate USD 104 million to TB Alliance
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/5/2016)... New York (PRWEB) , ... February 05, 2016 , ... ... use and find themselves having to wait longer to access the treadmills. It’s a ... New Year’s resolutions to lose weight and get in shape by joining gyms, starting ...
(Date:2/5/2016)... ... , ... At its annual meeting held last week, the American Parkinson Disease ... of Directors. Mr. McDermott succeeds former APDA Chairman, Fred Greene. , "We are pleased ... APDA President and CEO. “Pat has tirelessly served APDA since 2001 when he was ...
(Date:2/5/2016)... , ... February 05, 2016 , ... Colorize ... on one drop zone to the next using Colorize's dynamic moving camera. Colorize is ... This package includes a 3D slideshow environment with 1 to 5 focus points per ...
(Date:2/5/2016)... ... 05, 2016 , ... On June 9-10, Las Vegas will ... education (CME) event presented by the Association for Comprehensive Care in Rare Diseases ... whose mission is to provide education, tools, and resources to primary care clinicians ...
(Date:2/5/2016)... Luis Obispo, CA (PRWEB) , ... February 05, 2016 , ... ... new changes that Medicare San Luis Obispo users can expect to see in 2016. ... , The two most significant changes will directly impact many San Luis Obispo seniors ...
Breaking Medicine News(10 mins):
(Date:2/4/2016)... , Feb. 4, 2016 Worldwide ... achieve significant growth as next generation systems provide ... use radiology for cancer surgery. New systems pinpoint ... overdosing that has been such a problem previously, ... delivered. Radiosurgery robots take cancer surgery far beyond ...
(Date:2/4/2016)... 2016 Wegener Polyangiitis - Pipeline Review, ... ,Wegener Polyangiitis - Pipeline Review, H2 2015, provides ... This report provides comprehensive information on the ... analysis at various stages, therapeutics assessment by drug ... (RoA) and molecule type, along with latest updates, ...
(Date:2/4/2016)... LONDON , Feb. 4, 2016 ... and competitive market to drive long-term market growth ... very common set of chronic disorders that affect ... disparate in terms of their symptoms and key ... by dysregulation of immune pathways and an inappropriate ...
Breaking Medicine Technology: