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Metastasis of Neuroblastoma linked to Loss Of Caspase-8 gene

sis to ovary, adrenal gland, kidney and liver were seen. These metastasizing cells were tested and they were found to have lost the expression of the caspase-8 gene. But this gene did not affect the growth of the tumor cells.

One important discovery that was made is that when the gene is present a number of cells present outside the tumor underwent apoptosis. This of great value for patients suffering from metastasizing neuroblastoma as it will help in the development of new treatment modalities.
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