Navigation Links
Menin Gene Mutation made Insulin Secreting Cells to Proliferate

eads to endocrine tumors,’ explains Hua.

In type I diabetes, the loss of islet beta cells is the leading reason why a sufficient amount of insulin cannot be produced. ‘If we could eventually repress menin function to specifically stimulate beta-cell proliferation, this may facilitate devising new strategies to increase insulin-secreting beta cells and treating diabetes,’ notes Hua.

‘We did not expect the connection between a study about a tumor suppressor and a potential new avenue for treating diabetes,’ he adds. ‘By taking advantage of studying a genetically well-characterized tumor syndrome, MEN1, we set out to understand how the first step of benign tumor development is precisely controlled. The more we discovered about menin function, the better we understood the precise role of menin in regulating islet cell proliferation. This latest finding about the acute and specific role of menin on repressing islet cells, but not adjacent exocrine cells, led to the realization that manipulating the menin pathway might be a powerful way to stimulate islet cell proliferation to fight type I diabetes, although we are just beginning toward that goal.’

Study co-authors are Robert B. Schnepp, Ya-Xiong, Haoren Wang, Tim Cash, Albert Silva, Alan Diehl, and Eric Brown, with participation from the members of Dr. Eric Brown's lab and Dr. Alan Diehl's lab, all from Penn. This research was funded by the National Institutes of Health.

Source:Eurekalert
'"/>




Page: 1 2

Related medicine news :

1. Meningitis C vaccine a cost-effective success
2. Cure for Bacterial Meningitis
3. Efficacy Of Meningitis C Vaccine
4. Meningitis is rocking the capital again
5. Uganda Tackles The Meningitis Outbreak
6. Fatal Case of Meningitis Detected In Massachusetts
7. Meningitis Back in Delhi and 21 Dead
8. New Delhi Hit By Meningitis Deaths
9. Cost-effective Meningitis Vaccine To Be Launched In Africa
10. Possibility Of A Meningococcal Outbreak In NSW
11. Delhi Witnessed 34 Meningitis Deaths In Three Months
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Menin Gene Mutation made Insulin Secreting Cells Proliferate

(Date:5/6/2015)... Vancouver Chiropractic Clinic, Backs in ... blog containing the Canadian Physical Activity and Sedentary ... for Exercise Physiology (CSEP). Since the CSEP is ... fitness research and personal training in Canada, its ... beneficial and a rich resource for many people. ...
(Date:5/6/2015)... California (PRWEB) May 06, 2015 ... hand sanitizers are increasing, driven by the rising consumer ... the spread of contagious diseases. Hand washing is becoming ... of consumer apprehension over contracting infections. Periodic outbreak of ... the recent Ebola virus disease (EVD) epidemic ...
(Date:5/6/2015)... 06, 2015 Healthcare jobs ... after launching in mid-February. The company connects hospitals, home-health, ... previous experience in the industry. Likewise, job seekers are ... to Kyle Johnson, CTO, unique traffic to the site ... month: "Each new job posting brings targeted, interested candidates ...
(Date:5/6/2015)... 2015 TU-Automotive has opened press registration ... vehicles make it to the headlines of major publications ... GM, Volvo and Hyundai ready to share their visions ... the only way for press to go behind the ... marketing director, TU-Automotive said “This year we’re releasing a ...
(Date:5/6/2015)... 06, 2015 The 2015 STEMtech conference ... Corporate Partner booth selection . Don’t miss this ... community college and university decision-makers from around the country. ... 2015, at the Arizona Grand in Phoenix. This beautiful ... on the doorstep of the South Mountain Preserve. The ...
Breaking Medicine News(10 mins):Health News:Vancouver Chiropractor Shares Canadian Physical Activity and Sedentary Behavior Guidelines by CSEP in New Blog 2Health News:Growing Apprehension Amid Disease Outbreaks Drives Global Sales of Hand Sanitizers, According to a New Report by Global Industry Analysts, Inc. 2Health News:Growing Apprehension Amid Disease Outbreaks Drives Global Sales of Hand Sanitizers, According to a New Report by Global Industry Analysts, Inc. 3Health News:Growing Apprehension Amid Disease Outbreaks Drives Global Sales of Hand Sanitizers, According to a New Report by Global Industry Analysts, Inc. 4Health News:Job Seekers Turn to JobMedic to Find Healthcare Positions - JobMedic.com Reaches 1,000 User Milestone 2Health News:Press Registration for TU-Automotive Detroit Now Open 2Health News:STEMtech Conference Exhibitors Gain Access to Community College and University Representatives From Across the U.S. 2
... April 3, 2008 The 2nd,U.S. Circuit Court of ... class-action suit brought against cigarette makers, decertifying,the nationwide class ... "Because individual issues outweigh,issues susceptible to common proof, the ... certainly pleased with the court,s ruling and agree with ...
... April 3, 2008 QED International Associates,Inc., administrator ... indexes for the HealthShares(TM) Exchange-Traded Funds, today,announced that ... April 7, 2008,BARCO (BAR.BR) will replace Possis Medical, ... Devices Index. Possis is being acquired by Bayer ...
... material in excrement linking New World to Siberia, East ... oldest human DNA ever found in the Americas appears ... according to an international team of scientists. , ... discovered in 14,300-year-old dried human excrement, called coprolites, ...
... (Race Day: April 13 at 7 ... competitor who was diagnosed with type 1 ... this Sunday,s triathlon to encourage others who have chronic ... and to live without limits., ...
... Pediatric, Oncology for Novel Approaches for Using X-ray Based Radiation ... ... 3, 2008 Xoft consulting,medical director, Mark Carol, MD, has received ... focused on novel,approaches for using KV X-ray-based radiation therapy to treat ...
... Electrolux & Kelly Ripa Team Up to Promote New Appliance Line,s European, ... for The ... Research Fund -, NEW YORK, April 3, 2008 Known and ... that it is tapping Kelly Ripa for the North America launch of ...
Cached Medicine News:Health News:DNA Find in Oregon Is Oldest Yet Discovered in Americas 2Health News:Ironman Competitor with Diabetes Encourages Others to Live Without Limits; Competes in Ironman Arizona in Tempe 2Health News:Xoft Medical Director Recognized by Gotham Prize for Cancer Research 2Health News:Xoft Medical Director Recognized by Gotham Prize for Cancer Research 3Health News:Europe's Leading Premium Appliance Brand Taps America's Most Stylish, Multi-Tasking Mom to Launch New Appliance Line in North America 2Health News:Europe's Leading Premium Appliance Brand Taps America's Most Stylish, Multi-Tasking Mom to Launch New Appliance Line in North America 3Health News:Europe's Leading Premium Appliance Brand Taps America's Most Stylish, Multi-Tasking Mom to Launch New Appliance Line in North America 4
(Date:5/6/2015)... --Research and Markets ( http://www.researchandmarkets.com/research/rd24gk/chromatography ) ... (Instruments and Reagents) Global Market - Forecast to ... Chromatography is an analytical technique, a method of ... mixture by differential movement through a two phase ... chromatography as an esoteric art, which mainly involves ...
(Date:5/6/2015)... , May 06, 2015 Research and Markets ... addition of the "Global Insulin Patch Market ... Highly advanced technology like ultrasound and iontophoresis ... insulin patches. Depending upon the type of technique, ... of reach of several patients. In long-term, it ...
(Date:5/6/2015)... , UAE, May 6, 2015 ... management solutions, has been named a "Cool Vendor" by top ... in Emerging Markets 2015". Gartner defines a "Cool ... are innovative, impactful and intriguing. The report highlights ... whose organizations operate in emerging markets should look at local ...
Breaking Medicine Technology:Global Chromatography (Instruments and Reagents) Market 2015 - Forecasts to 2019 2Global Insulin Patch Market Opportunity Analysis 2015 2UAE-Based Software Developer Named by Gartner as a Cool Vendor 2UAE-Based Software Developer Named by Gartner as a Cool Vendor 3UAE-Based Software Developer Named by Gartner as a Cool Vendor 4
... 2011 PolyOne Corporation (NYSE: POL ) announced ... Chlor Alkali Partnership to Olin Corporation.   SunBelt, ... in 1996 between PolyOne (formerly The Geon Company) and Olin. ... million, including $132 million in cash and the assumption of ...
... 2011 VIVUS, Inc. (Nasdaq: VVUS ... of novel therapeutic products, today reported its highlights and financial ... 2010. 2010 Highlights ... the two-year SEQUEL study, an extension study in 675 patients ...
Cached Medicine Technology:PolyOne Announces Sale of SunBelt Investment 2PolyOne Announces Sale of SunBelt Investment 3VIVUS Reports 2010 Fourth Quarter and Full-Year Financial Results 2VIVUS Reports 2010 Fourth Quarter and Full-Year Financial Results 3VIVUS Reports 2010 Fourth Quarter and Full-Year Financial Results 4VIVUS Reports 2010 Fourth Quarter and Full-Year Financial Results 5VIVUS Reports 2010 Fourth Quarter and Full-Year Financial Results 6VIVUS Reports 2010 Fourth Quarter and Full-Year Financial Results 7
Wire lid retractor may be clamped to surgical drape with suture or elastic band. Large pair....
Sharp. 4 mm wide. Hand-Held...
Rigid rake retractor, 3 blunt prongs....
Rees bayonet forceps, standard, 5-1/2", TC....
Medicine Products: